biology thesis projects

BIOLOGICAL SCIENCES MAJOR

Senior thesis examples.

Graduating seniors in Biological Sciences have the option of submitting a senior thesis for consideration for Honors and Research Prizes .  Below are some examples of particularly outstanding theses from recent years (pdf):

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Recent Submissions

Plasticity of ageing in burying beetles , exploring strategies to address trypanocide resistance: lessons from uganda , investigating the roles of classic and unusual rna-binding proteins in staphylococcus aureus survival in hostile environments , exploring the role of three deubiquitinases – uch54, uchl3 and usp7 – in the biology of the malaria parasite , protein crystallisation using low-cost electric-field assisted setups for microbatch, vapour diffusion, and in situ diffraction studies , mechanisms regulating human platelet cytoskeleton dynamics and shape change , investigating mechanisms of synaptic loss in progressive supranuclear palsy , post-transcriptional roles of helix-turn-helix transcription factors in regulation of gene expression in methicillin-resistant staphylococcus aureus , development of a biocompatible lossen rearrangement in escherichia coli , spatial regulation of spindle-associated proteins in oocytes , approximation methods for stochastic systems biology , exploring the role of s-nitrosylation regulators hvgsnor and hvtrxh2 in the barley immune response to blumeria graminis f. sp. hordei , watch-breaker: establishment of a microwell array-based miniaturized thymic organoid model suitable for high throughput applications , bacterial removal of co, ni and mn metals from li-ion battery leachates , modern invasions within the western palearctic: cynipid gallwasps as study models for the development of parasitoid communities , using phylodynamics to inform and evaluate hiv public health interventions across three distinct epidemics , post-transcriptional regulation of fungal cell walls by rna-binding proteins and untranslated regions , evolution of recombination rate variation in a natural population of house sparrows , identification of mutants that affect mono-orientation in meiosis through a mutagenesis screen , investigation of rnai-dependent heterochromatin establishment in schizosaccharomyces pombe .

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49 Most Interesting Biology Research Topics

August 21, 2023

In need of the perfect biology research topics—ideas that can both showcase your intellect and fuel your academic success? Lost in the boundless landscape of possible biology topics to research? And afraid you’ll never get a chance to begin writing your paper, let alone finish writing? Whether you’re a budding biologist hoping for a challenge or a novice seeking easy biology research topics to wade into, this blog offers curated and comprehensible options.

And if you’re a high school or transfer student looking for opportunities to immerse yourself in biology, consider learning more about research opportunities for high school students , top summer programs for high school students , best colleges for studying biomedical engineering , and best colleges for studying biology .

What is biology?

Well, biology explores the web of life that envelops our planet, from the teeny-tiny microbes to the big complex ecosystems. Biology investigates the molecular processes that define existence, deciphers the interplay of genes, and examines all the dynamic ways organisms interact with their environments. And through biology, you can gain not only knowledge, but a deeper appreciation for the interconnectedness of all living things. Pretty cool!

There are lots and lots of sub-disciplines within biology, branching out in all directions. Throughout this list, we won’t follow all of those branches, but we will follow many. And while none of these branches are truly simple or easy, some might be easier than others. Now we’ll take a look at a few various biology research topics and example questions that could pique your curiosity.

Climate change and ecosystems

The first of our potentially easy biology research topics: climate change and ecosystems. Investigate how ecosystems respond and adapt to the changing climate. And learn about shifts in species distributions , phenology , and ecological interactions .

1) How are different ecosystems responding to temperature changes and altered precipitation patterns?2) What are the implications of shifts in species distributions for ecosystem stability and functioning?

2) Or how does phenology change in response to climate shifts? And how do those changes impact species interactions?

3) Which underlying genetic and physiological mechanisms enable certain species to adapt to changing climate conditions?

4) And how do changing climate conditions affect species’ abilities to interact and form mutualistic relationships within ecosystems?

Microbiome and human health

Intrigued by the relationship between the gut and the rest of the body? Study the complex microbiome . You could learn how gut microbes influence digestion, immunity, and even mental health.

5) How do specific gut microbial communities impact nutrient absorption?

6) What are the connections between the gut microbiome, immune system development, and susceptibility to autoimmune diseases?

7) What ethical considerations need to be addressed when developing personalized microbiome-based therapies? And how can these therapies be safely and equitably integrated into clinical practice?

8) Or how do variations in the gut microbiome contribute to mental health conditions such as anxiety and depression?

9) How do changes in diet and lifestyle affect the composition and function of the gut microbiome? And what are the subsequent health implications?

Urban biodiversity conservation

Next, here’s another one of the potentially easy biology research topics. Examine the challenges and strategies for conserving biodiversity in urban environments. Consider the impact of urbanization on native species and ecosystem services. Then investigate the decline of pollinators and its implications for food security or ecosystem health.

10) How does urbanization influence the abundance and diversity of native plant and animal species in cities?

11) Or what are effective strategies for creating and maintaining green spaces that support urban biodiversity and ecosystem services?

12) How do different urban design and planning approaches impact the distribution of wildlife species and their interactions?

13) What are the best practices for engaging urban communities in biodiversity conservation efforts?

14) And how can urban agriculture and rooftop gardens contribute to urban biodiversity conservation while also addressing food security challenges?

Bioengineering

Are you a problem solver at heart? Then try approaching the intersection of engineering, biology, and medicine. Delve into the field of synthetic biology , where researchers engineer biological systems to create novel organisms with useful applications.

15) How can synthetic biology be harnessed to develop new, sustainable sources of biofuels from engineered microorganisms?

16) And what ethical considerations arise when creating genetically modified organisms for bioremediation purposes?

17) Can synthetic biology techniques be used to design plants that are more efficient at withdrawing carbon dioxide from the atmosphere?

18) How can bioengineering create organisms capable of producing valuable pharmaceutical compounds in a controlled and sustainable manner?

19) But what are the potential risks and benefits of using engineered organisms for large-scale environmental cleanup projects?

Neurobiology

Interested in learning more about what makes creatures tick? Then this might be one of your favorite biology topics to research. Explore the neural mechanisms that underlie complex behaviors in animals and humans. Shed light on topics like decision-making, social interactions, and addiction. And investigate how brain plasticity and neurogenesis help the brain adapt to learning, injury, and aging.

20) How does the brain’s reward circuitry influence decision-making processes in situations involving risk and reward?

21) What neural mechanisms underlie empathy and social interactions in both humans and animals?

22) Or how do changes in neural plasticity contribute to age-related cognitive decline and neurodegenerative diseases?

23) Can insights from neurobiology inform the development of more effective treatments for addiction and substance abuse?

24) What are the neural correlates of learning and memory? And how can our understanding of these processes be applied to educational strategies?

Plant epigenomics

While this might not be one of the easy biology research topics, it will appeal to plant enthusiasts. Explore how epigenetic modifications in plants affect their ability to respond and adapt to changing environmental conditions.

25) How do epigenetic modifications influence the expression of stress-related genes in plants exposed to temperature fluctuations?

26) Or what role do epigenetic changes play in plants’ abilities to acclimate to changing levels of air pollution?

27) Can certain epigenetic modifications be used as indicators of a plant’s adaptability to new environments?

28) How do epigenetic modifications contribute to the transgenerational inheritance of traits related to stress resistance?

29) And can targeted manipulation of epigenetic marks enhance crop plants’ ability to withstand changing environmental conditions?

Conservation genomics

Motivated to save the planet? Conservation genomics stands at the forefront of modern biology, merging the power of genetics with the urgent need to protect Earth’s biodiversity. Study genetic diversity, population dynamics, and how endangered species adapt in response to environmental changes.

30) How does genetic diversity within endangered species influence their ability to adapt to changing environmental conditions?

31) What genetic factors contribute to the susceptibility of certain populations to diseases, and how can this knowledge inform conservation strategies?

32) How can genomic data be used to inform captive breeding and reintroduction programs for endangered species?

33) And what are the genomic signatures of adaptation in response to human-induced environmental changes, such as habitat fragmentation and pollution?

34) Or how can genomics help identify “hotspots” of biodiversity that are particularly important for conservation efforts?

Zoonotic disease transmission

And here’s one of the biology research topics that’s been on all our minds in recent years. Investigate the factors contributing to the transmission of zoonotic diseases , like COVID-19. Then posit strategies for prevention and early detection.

35) What are the ecological and genetic factors that facilitate the spillover of zoonotic pathogens from animals to humans?

36) Or how do changes in land use, deforestation, and urbanization impact the risk of zoonotic disease emergence?

37) Can early detection and surveillance systems be developed to predict and mitigate the spread of zoonotic diseases?

38) How do social and cultural factors influence human behaviors that contribute to zoonotic disease transmission?

39) And can strategies be implemented to improve global pandemic preparedness?

Bioinformatics

Are you a data fanatic? Bioinformatics involves developing computational tools and techniques to analyze and interpret large biological datasets. This enables advancements in genomics, proteomics, and systems biology. So delve into the world of bioinformatics to learn how large-scale genomic and molecular data are revolutionizing biological research.

40) How can machine learning algorithms predict the function of genes based on their DNA sequences?

41) And what computational methods can identify potential drug targets by analyzing protein-protein interactions in large biological datasets?

42) Can bioinformatics tools be used to identify potential disease-causing mutations in human genomes and guide personalized medicine approaches?

43) What are the challenges and opportunities in analyzing “omics” data (genomics, proteomics, transcriptomics) to uncover novel biological insights?

44) Or how can bioinformatics contribute to our understanding of microbial diversity, evolution, and interactions within ecosystems?

Regenerative medicine

While definitely not one of the easy biology research topics, regenerative medicine will appeal to those interested in healthcare. Research innovative approaches to stimulate tissue and organ regeneration, using stem cells, tissue engineering, and biotechnology. And while you’re at it, discover the next potential medical breakthrough.

45) How can stem cells be directed to differentiate into specific cell types for tissue regeneration, and what factors influence this process?

46) Or what are the potential applications of 3D bioprinting in creating functional tissues and organs for transplantation?

47) How can bioengineered scaffolds enhance tissue regeneration and integration with host tissues?

48) What are the ethical considerations surrounding the use of stem cells and regenerative therapies in medical treatments?

49) And can regenerative medicine approaches be used to treat neurodegenerative disorders and restore brain function?

Biology Research Topics – Final thoughts

So as you take your next steps, try not to feel overwhelmed. And instead, appreciate the vast realm of possibilities that biology research topics offer. Because the array of biology topics to research is as diverse as the ecosystems it seeks to understand. And no matter if you’re only looking for easy biology research topics, or you’re itching to unravel the mysteries of plant-microbe interactions, your exploration will continue to deepen what we know of the world around us.

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Science Thesis Topics

300 Science Thesis Topics and Ideas

Science is a vast and ever-evolving field that encompasses numerous disciplines and research areas. From the complexities of molecular biology to the abstract theories of applied mathematics, science provides a broad range of opportunities for inquiry. A strong thesis topic is essential for contributing to the advancement of scientific knowledge, addressing current challenges, and shaping future innovations. This list of 300 science thesis topics, divided into 10 categories, covers key scientific disciplines and reflects current issues, emerging trends, and future directions in science.

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Get 10% off with 24start discount code, 1. applied mathematics thesis topics.

• The role of stochastic processes in financial modeling.
• Mathematical optimization techniques for energy-efficient transportation systems.
• Application of game theory in decision-making processes.
• The use of machine learning algorithms in solving complex differential equations.
• Exploring fractals in nature: Mathematical models and applications.
• Topological methods for data analysis in high-dimensional spaces.
• Mathematical modeling of infectious disease outbreaks.
• The role of computational geometry in computer vision.
• Optimization algorithms in machine learning.
• The impact of nonlinear dynamics on weather forecasting models.
• Mathematical models for understanding traffic flow dynamics.
• The use of graph theory in social network analysis.
• Chaos theory applications in environmental systems.
• Mathematical models of quantum computing processes.
• The role of partial differential equations in describing fluid dynamics.
• Investigating mathematical approaches to cryptography and secure communications.
• Mathematical modeling of population dynamics in ecology.
• Applications of number theory in cryptographic systems.
• Mathematical theories behind artificial neural networks.
• The application of Markov chains in queueing theory.
• Understanding the mathematics behind black hole thermodynamics.
• The role of calculus in understanding electromagnetic fields.
• Mathematical approaches to solving real-world logistics and supply chain problems.
• Statistical models for risk assessment in finance and insurance.
• Exploring differential geometry in the context of general relativity.
• The application of game theory to environmental economics.
• Investigating Monte Carlo methods for stochastic simulations.
• Using graph theory for optimal network design in telecommunications.
• Mathematical approaches to optimization problems in artificial intelligence.
• Analyzing the role of Fourier transforms in signal processing.

2. Biology Thesis Topics

• The role of CRISPR technology in gene editing and its ethical implications.
• Investigating the effects of climate change on biodiversity in tropical ecosystems.
• The impact of microplastics on marine organisms and ecosystems.
• Genetic factors contributing to cancer resistance in certain species.
• The role of the microbiome in human health and disease.
• Investigating stem cell therapy for the treatment of neurodegenerative diseases.
• Exploring the genetic basis of antibiotic resistance in bacteria.
• The impact of habitat fragmentation on species survival and reproduction.
• The role of epigenetics in developmental biology.
• Investigating the molecular mechanisms of aging in mammals.
• The role of photosynthesis in global carbon cycles and climate regulation.
• The effects of invasive species on native biodiversity and ecosystem functions.
• Exploring the molecular pathways involved in immune system regulation.
• The role of RNA interference in regulating gene expression.
• Investigating the evolutionary mechanisms driving speciation in isolated populations.
• The impact of pollution on reproductive health in amphibians.
• Investigating the genetic basis of human diseases using model organisms.
• The role of protein folding in neurodegenerative diseases like Alzheimer’s.
• Exploring plant adaptations to extreme environments such as deserts.
• Investigating the relationship between genetics and behavior in animal populations.
• The role of biodiversity in maintaining ecosystem services.
• Investigating the molecular mechanisms of disease resistance in plants.
• The impact of deforestation on animal migration patterns.
• Investigating the role of hormones in animal reproductive behaviors.
• The impact of climate change on migration patterns of birds and insects.
• The role of biotechnology in developing sustainable agricultural practices.
• Investigating the role of bioinformatics in identifying disease biomarkers.
• The effects of nanotechnology on biological systems and health.
• Exploring gene therapy approaches for treating inherited genetic disorders.
• The role of bioluminescence in marine ecosystems and its potential applications.

3. Botany Thesis Topics

• Investigating the effects of climate change on plant phenology.
• The role of plant hormones in regulating growth and development.
• Exploring plant responses to drought stress at the molecular level.
• Investigating the role of mycorrhizal fungi in plant nutrient uptake.
• The impact of invasive plant species on native ecosystems.
• Exploring the potential of genetically modified crops for sustainable agriculture.
• The role of plant secondary metabolites in defense against herbivores.
• Investigating plant-pollinator interactions in fragmented habitats.
• The effects of soil composition on plant growth and health.
• The role of photosynthesis in plant adaptation to changing environments.
• Investigating the impact of air pollution on plant physiology.
• Exploring plant symbiosis with nitrogen-fixing bacteria in agriculture.
• Investigating the role of polyploidy in plant evolution.
• The effects of light intensity on plant growth and development.
• The role of genetic diversity in the survival of plant populations.
• Investigating the potential of medicinal plants in drug discovery.
• Exploring plant adaptation strategies in arid environments.
• The role of epigenetic modifications in plant stress responses.
• Investigating the role of endophytes in plant health and disease resistance.
• The effects of heavy metal contamination on plant growth and soil health.
• Exploring the genetic basis of seed dormancy in wild and cultivated plants.
• The role of allelopathy in plant competition and ecosystem dynamics.
• Investigating the impact of climate change on alpine plant species.
• Exploring plant-based solutions for soil erosion control.
• Investigating the role of hormones in plant defense mechanisms.
• The potential of vertical farming for sustainable food production.
• Exploring plant responses to salinity stress in coastal ecosystems.
• The role of transgenic plants in bioremediation of polluted environments.
• Investigating plant biodiversity in tropical rainforests and its conservation.
• The effects of herbicides on non-target plant species and ecosystems.

4. Chemistry Thesis Topics

• Investigating the role of catalysts in green chemistry.
• The impact of nanomaterials on drug delivery systems.
• Exploring the chemistry behind renewable energy storage solutions.
• The role of chemical sensors in detecting environmental pollutants.
• Investigating the chemistry of bioplastics and their environmental impact.
• Exploring chemical reactions in atmospheric chemistry and climate change.
• The role of chemical compounds in developing antiviral drugs.
• Investigating the molecular structure of proteins using X-ray crystallography.
• Exploring the use of green solvents in organic synthesis.
• The role of photochemistry in developing solar energy technologies.
• Investigating the role of transition metals in catalysis.
• Exploring chemical methods for water purification and desalination.
• The impact of chemical pollutants on human health and ecosystems.
• Investigating the properties of supercapacitors for energy storage.
• The role of organic chemistry in drug design and development.
• Exploring the chemistry of rare earth elements in electronic devices.
• Investigating the chemistry of lithium-ion batteries for electric vehicles.
• The role of molecular simulations in understanding chemical reactions.
• Investigating the chemical basis of enzyme catalysis in biological systems.
• Exploring chemical approaches to carbon capture and storage technologies.
• Investigating the role of polymers in biomedical applications.
• The impact of chemical fertilizers on soil health and plant growth.
• Exploring the use of quantum chemistry in understanding molecular behavior.
• Investigating the role of chemical sensors in monitoring air quality.
• The role of synthetic organic chemistry in the development of pharmaceuticals.
• Investigating the chemistry of antioxidants and their effects on human health.
• Exploring the impact of industrial chemical processes on global warming.
• The role of computational chemistry in drug discovery.
• Investigating chemical pathways for converting biomass into biofuels.
• Exploring the chemistry of corrosion and its prevention in engineering materials.

5. Environmental Science Thesis Topics

• Investigating the impact of climate change on coastal ecosystems.
• The role of renewable energy in reducing global carbon emissions.
• The effects of deforestation on biodiversity in tropical rainforests.
• Exploring sustainable agricultural practices to combat soil degradation.
• The role of environmental policies in mitigating air pollution in urban areas.
• Investigating the effects of plastic pollution on marine ecosystems.
• The role of environmental education in promoting sustainable behavior.
• Exploring the impact of urbanization on freshwater resources.
• The role of wetlands in carbon sequestration and climate regulation.
• Investigating the potential of biofuels as a sustainable energy source.
• The effects of mining activities on groundwater contamination.
• Exploring the role of green infrastructure in urban flood management.
• Investigating the impact of agricultural pesticides on pollinator populations.
• The role of international environmental agreements in addressing climate change.
• The effects of ocean acidification on coral reefs and marine biodiversity.
• Exploring the impact of ecotourism on conservation efforts in protected areas.
• Investigating the role of forests in regulating global water cycles.
• The impact of climate-induced migration on political stability in developing countries.
• Exploring the role of public policy in promoting renewable energy adoption.
• The effects of microplastics on the food chain and human health.
• Investigating the potential of circular economy models in reducing waste.
• The role of reforestation in combating desertification in arid regions.
• The impact of extreme weather events on agricultural productivity.
• Exploring the role of environmental NGOs in global conservation efforts.
• Investigating the effects of urban sprawl on wildlife habitats.
• The role of environmental justice in addressing the disproportionate impact of pollution on marginalized communities.
• Exploring the potential of carbon offset markets in reducing global emissions.
• Investigating the role of environmental law in protecting endangered species.
• The impact of climate change on global food security.
• Exploring the role of ecosystem services in promoting sustainable development.

6. Geography Thesis Topics

• Investigating the role of geographical information systems (GIS) in disaster management.
• The impact of urbanization on landscape changes and environmental degradation.
• Exploring the effects of climate change on glacier retreat and water resources.
• The role of geographic factors in the spread of infectious diseases.
• Investigating the socio-economic impacts of gentrification in urban areas.
• Exploring the relationship between deforestation and rural poverty in developing countries.
• The role of geography in shaping patterns of human migration and resettlement.
• Investigating the impact of coastal erosion on communities and infrastructure.
• The role of remote sensing in monitoring environmental change.
• Exploring the spatial distribution of renewable energy resources across the globe.
• Investigating the geographic factors influencing access to healthcare in rural areas.
• The impact of climate change on agriculture and food production in different regions.
• Exploring the role of geography in international trade and global supply chains.
• Investigating the effects of urban planning on transportation networks in major cities.
• The role of GIS in assessing the risk of natural disasters such as floods and earthquakes.
• Exploring the geographic distribution of endangered species and conservation efforts.
• Investigating the influence of geography on political boundaries and border disputes.
• The impact of tourism on the environment and local economies in coastal regions.
• Exploring the role of climate change in shaping migration patterns in developing countries.
• Investigating the effects of population growth on land use and environmental sustainability.
• The role of geography in shaping cultural identity and regional development.
• Exploring the geographic factors influencing energy consumption patterns.
• Investigating the spatial distribution of poverty and wealth in urban areas.
• The impact of global warming on sea level rise and coastal vulnerability.
• Exploring the role of geographic factors in conflict and political instability.
• Investigating the impact of natural disasters on population displacement and migration.
• The role of geography in shaping patterns of inequality in education and healthcare.
• Exploring the geographic implications of resource extraction in developing countries.
• Investigating the effects of globalization on rural and urban landscapes.
• The role of GIS in urban planning and sustainable development.

7. Geology Thesis Topics

• Investigating the formation of volcanic islands and their geological features.
• The role of plate tectonics in shaping the Earth’s landscape and geological formations.
• Exploring the effects of soil erosion on agricultural productivity and land degradation.
• The impact of mining activities on geological structures and ecosystems.
• Investigating the role of groundwater in shaping karst landscapes.
• The effects of climate change on permafrost and its implications for infrastructure.
• Exploring the geological history of mass extinction events and their causes.
• Investigating the role of sedimentation in coastal and river delta formations.
• The impact of earthquakes on geological faults and seismic activity.
• Exploring the role of glaciers in shaping mountain landscapes.
• Investigating the formation and distribution of fossil fuels in sedimentary basins.
• The role of geologic processes in the formation of mineral deposits.
• Exploring the impact of human activities on the stability of geological formations.
• Investigating the role of volcanic activity in shaping oceanic islands.
• The effects of deforestation on soil stability and erosion in mountainous regions.
• Exploring the role of geologic processes in the formation of natural gas reserves.
• Investigating the impact of volcanic eruptions on climate and atmospheric conditions.
• The role of geology in understanding and predicting natural hazards such as landslides.
• Exploring the geological history of the Earth’s climate and its impact on life.
• Investigating the role of subduction zones in the formation of mountain ranges.
• The impact of sea-level rise on coastal geology and sedimentation patterns.
• Exploring the formation of caves and underground water systems in karst regions.
• Investigating the effects of glaciation on soil composition and landscape features.
• The role of geology in assessing the risks of earthquakes and tsunamis in coastal areas.
• Exploring the formation of metamorphic rocks and their role in the Earth’s crust.
• Investigating the impact of mining on groundwater contamination and geological stability.
• The role of geology in understanding the Earth’s magnetic field and its changes over time.
• Exploring the formation of deserts and the geological processes that shape them.
• Investigating the role of geological surveys in the exploration of natural resources.
• The impact of geological changes on ecosystems and biodiversity over geological time.

8. Molecular Biology Thesis Topics

• Investigating the molecular mechanisms of DNA repair in response to UV radiation.
• The role of transcription factors in gene expression and regulation.
• Exploring the molecular basis of cancer cell resistance to chemotherapy.
• Investigating the role of microRNAs in regulating cellular differentiation.
• The molecular mechanisms of protein folding and misfolding in neurodegenerative diseases.
• Exploring the molecular pathways involved in cell cycle regulation and cancer.
• Investigating the role of epigenetic modifications in gene expression and inheritance.
• The molecular basis of antibiotic resistance in pathogenic bacteria.
• Exploring the molecular mechanisms of immune system activation and response.
• Investigating the role of molecular chaperones in protein folding and stability.
• The molecular pathways involved in apoptosis and programmed cell death.
• Exploring the molecular mechanisms of viral replication and host cell invasion.
• Investigating the role of molecular signaling pathways in stem cell differentiation.
• The molecular basis of genetic mutations and their role in hereditary diseases.
• Exploring the molecular mechanisms of plant immune responses to pathogens.
• Investigating the role of molecular interactions in enzyme catalysis and regulation.
• The molecular basis of gene editing technologies such as CRISPR-Cas9.
• Exploring the molecular pathways involved in aging and cellular senescence.
• Investigating the role of molecular motors in intracellular transport and cell division.
• The molecular basis of signal transduction pathways in cancer cells.
• Exploring the molecular mechanisms of hormone signaling in plants and animals.
• Investigating the molecular basis of synaptic plasticity and memory formation.
• The role of molecular biology in developing targeted therapies for genetic disorders.
• Exploring the molecular mechanisms of viral evasion of the immune system.
• Investigating the role of molecular clocks in understanding evolutionary processes.
• The molecular basis of immune tolerance and autoimmunity.
• Exploring the role of molecular biology in understanding the genetics of rare diseases.
• Investigating the molecular basis of drug resistance in cancer cells.
• The role of molecular biology in understanding the regulation of metabolic pathways.
• Exploring the molecular mechanisms of gene-environment interactions in human diseases.

9. Physics Thesis Topics

• Investigating the role of quantum mechanics in understanding black hole thermodynamics.
• The impact of dark matter on the formation of galaxies and cosmic structures.
• Exploring the physics behind superconductivity and its potential applications.
• Investigating the role of particle physics in understanding the fundamental forces of nature.
• The physics of climate change: Understanding the role of energy transfer in global warming.
• Exploring the principles of quantum computing and its applications in cryptography.
• Investigating the physics behind nuclear fusion as a potential energy source.
• The role of gravitational waves in understanding the structure of the universe.
• Exploring the physics of turbulence in fluids and its applications in engineering.
• Investigating the role of quantum entanglement in the development of quantum networks.
• The physics of renewable energy: Understanding the principles behind solar and wind energy.
• Exploring the role of general relativity in predicting the behavior of black holes.
• Investigating the physics of particle accelerators and their role in high-energy physics.
• The impact of quantum mechanics on understanding the behavior of atomic and subatomic particles.
• Exploring the principles of thermodynamics in understanding energy transfer and efficiency.
• Investigating the role of string theory in unifying the fundamental forces of nature.
• The physics of light and its applications in developing new technologies.
• Exploring the principles of quantum field theory in understanding the behavior of particles.
• Investigating the role of statistical mechanics in understanding the behavior of gases and liquids.
• The physics of space exploration: Understanding the principles behind rocket propulsion.
• Exploring the role of electromagnetism in developing new communication technologies.
• Investigating the physics behind the formation of stars and planetary systems.
• The impact of quantum mechanics on understanding the behavior of materials at the nanoscale.
• Exploring the principles of fluid dynamics in understanding the behavior of liquids and gases.
• Investigating the role of quantum mechanics in developing new technologies such as quantum sensors.
• The physics of time travel: Exploring the theoretical possibilities and challenges.
• Exploring the role of nuclear physics in understanding the behavior of atomic nuclei.
• Investigating the physics of solid-state materials and their applications in electronics.
• The role of quantum mechanics in understanding the behavior of complex systems.
• Exploring the principles of chaos theory in understanding the behavior of dynamic systems.

10. Zoology Thesis Topics

• Investigating the impact of climate change on animal migration patterns.
• The role of animal behavior in shaping predator-prey relationships.
• Exploring the effects of habitat loss on the biodiversity of endangered species.
• Investigating the role of genetics in animal adaptation to environmental changes.
• The impact of invasive species on native animal populations and ecosystems.
• Exploring the role of animal communication in social behaviors and survival strategies.
• Investigating the effects of pollution on reproductive health in marine animals.
• The role of animal cognition in problem-solving and decision-making.
• Exploring the impact of urbanization on wildlife behavior and habitat use.
• Investigating the role of genetics in the evolution of animal species.
• The effects of climate change on animal breeding patterns and reproductive success.
• Exploring the role of conservation biology in protecting endangered species.
• Investigating the impact of human activities on the behavior and survival of marine mammals.
• The role of animal physiology in adapting to extreme environmental conditions.
• Exploring the relationship between animal nutrition and growth in different species.
• Investigating the role of social structures in shaping animal behavior in primates.
• The impact of deforestation on animal populations and their habitats.
• Exploring the role of animal behavior in shaping mating strategies and reproductive success.
• Investigating the effects of climate change on animal disease transmission and outbreaks.
• The role of animal behavior in shaping group dynamics and social hierarchies.
• Exploring the impact of habitat fragmentation on animal movement and dispersal.
• Investigating the role of genetics in animal domestication and breeding.
• The effects of human activities on animal migration routes and patterns.
• Exploring the role of animal behavior in predator-prey interactions in marine ecosystems.
• Investigating the impact of climate change on animal distribution and range shifts.
• The role of genetics in understanding animal behavior and cognition.
• Exploring the effects of climate change on the biodiversity of animal populations.
• Investigating the role of animal behavior in shaping mating systems and reproductive success.
• The impact of pollution on the behavior and survival of terrestrial animals.
• Exploring the role of animal behavior in shaping the dynamics of animal communities.

This comprehensive list of 300 science thesis topics offers students a diverse range of research opportunities across various scientific disciplines. Whether you are interested in applied mathematics, biology, chemistry, or environmental science, these topics address key challenges, emerging trends, and the future direction of scientific research. By selecting a topic from this list, students can contribute to groundbreaking research that shapes the future of science and technology, advancing both knowledge and innovation in their respective fields.

The Range of Science Thesis Topics

Science is one of the most dynamic and rapidly evolving fields, offering a wide array of research opportunities that span multiple disciplines. From the vast expanses of the universe to the microscopic world of molecular biology, science enables researchers to explore the unknown, solve critical global issues, and contribute to technological innovations that shape the future. For students pursuing degrees in various scientific fields, choosing a thesis topic is a critical step in shaping their academic and professional careers. The range of science thesis topics available today reflects the diversity of scientific inquiry and offers opportunities for students to engage in research that addresses current issues, follows recent trends, and explores future directions in their chosen field.

Current Issues in Science

In today’s world, science plays a pivotal role in solving many of the pressing global challenges we face, including environmental degradation, public health crises, and energy sustainability. Students in scientific disciplines have the opportunity to address these critical issues through their thesis research, contributing to solutions that can have a profound impact on society.

• Climate Change and Environmental Sustainability One of the most urgent global challenges is climate change, which affects ecosystems, economies, and human livelihoods. Scientific research focused on understanding the causes and consequences of climate change has become a top priority. Topics related to environmental sustainability include exploring the impact of greenhouse gas emissions on climate patterns, investigating the role of renewable energy in reducing carbon footprints, and studying the effects of deforestation on biodiversity. Additionally, students can explore the impact of human activities such as urbanization and industrialization on ecosystems and how policy interventions can mitigate these effects.
• Public Health and Global Pandemics The COVID-19 pandemic highlighted the critical need for scientific research in public health, epidemiology, and virology. Research in this area spans understanding the transmission of infectious diseases, developing vaccines, and investigating the long-term effects of viral outbreaks on human health. Thesis topics could focus on epidemiological modeling, the role of public health infrastructure in pandemic preparedness, or the genetic factors that contribute to disease resistance. Additionally, students can explore the social and economic impacts of public health crises and the role of governments and international organizations in responding to pandemics.
• Energy Crisis and Sustainable Development As global energy demand increases, there is a pressing need to transition from fossil fuels to renewable energy sources. Scientific research in this area is focused on developing efficient energy storage solutions, improving solar and wind energy technologies, and exploring the potential of biofuels and nuclear fusion as alternative energy sources. Thesis topics could explore the role of nanotechnology in enhancing solar cell efficiency, the impact of renewable energy adoption on economic growth, or the challenges of implementing large-scale renewable energy projects in developing countries.
• Conservation of Biodiversity The rapid loss of biodiversity is another critical issue facing the planet. Human activities such as habitat destruction, overfishing, and pollution have led to the extinction of species and the degradation of ecosystems. Thesis topics in this area could explore the role of conservation biology in protecting endangered species, the impact of climate change on species migration patterns, or the effectiveness of protected areas and wildlife reserves in conserving biodiversity. Additionally, students can investigate the role of genetics in understanding species adaptation to changing environments.
• Pollution and Environmental Health Pollution, including air, water, and soil contamination, poses serious risks to both human health and the environment. Scientific research aimed at understanding the sources and consequences of pollution is essential for developing effective mitigation strategies. Thesis topics could focus on the effects of microplastics on marine life, the role of industrial pollutants in water contamination, or the development of sustainable waste management practices. Additionally, students could explore the health impacts of air pollution in urban areas or the effectiveness of environmental policies aimed at reducing pollution levels.

Recent Trends in Science

The rapid advancement of technology and scientific understanding has given rise to new trends in scientific research, many of which are interdisciplinary in nature. Recent trends in science reflect the growing importance of collaboration between different scientific fields and the integration of cutting-edge technologies in research.

• Artificial Intelligence and Machine Learning in Scientific Research Artificial intelligence (AI) and machine learning (ML) are transforming the way scientific research is conducted. These technologies are being used in fields such as biology, physics, and chemistry to analyze large datasets, predict outcomes, and automate complex processes. In biology, for instance, AI is being used to analyze genomic data, predict protein structures, and develop new drug therapies. In physics, ML algorithms are being used to model complex systems and simulate the behavior of particles in quantum mechanics. Thesis topics could explore the application of AI in personalized medicine, the role of machine learning in climate modeling, or the ethical implications of using AI in scientific research.
• CRISPR and Genetic Engineering The development of CRISPR-Cas9 technology has revolutionized genetic engineering by providing a precise and efficient method for editing genes. This breakthrough has opened new avenues for research in genetics, biotechnology, and medicine. Thesis topics could focus on the potential applications of CRISPR in treating genetic disorders, the ethical considerations surrounding gene editing in humans, or the use of CRISPR to create genetically modified organisms for agriculture. Additionally, students could explore the role of CRISPR in studying evolutionary processes or its potential use in combating antibiotic resistance.
• Quantum Computing and Its Applications Quantum computing is emerging as a powerful tool in fields such as cryptography, chemistry, and materials science. Unlike classical computers, quantum computers use quantum bits (qubits) to perform calculations at an exponentially faster rate, making them ideal for solving complex problems that are currently beyond the reach of traditional computers. Thesis topics could explore the principles of quantum computing, its potential applications in developing new materials, or its role in advancing cryptography. Additionally, students could investigate the challenges of scaling quantum computers for practical use or the potential impact of quantum computing on industries such as finance and healthcare.
• Nanotechnology and Its Impact on Materials Science Nanotechnology involves the manipulation of matter at the atomic or molecular scale and has wide-ranging applications in fields such as medicine, energy, and electronics. In materials science, nanotechnology is being used to create stronger, lighter, and more durable materials with enhanced properties. Thesis topics could focus on the role of nanotechnology in developing energy-efficient materials, the use of nanoparticles in drug delivery systems, or the environmental implications of nanomaterials. Additionally, students could explore the potential of nanotechnology in creating sustainable solutions for water purification or renewable energy storage.
• Synthetic Biology and Biotechnology Synthetic biology combines biology and engineering to design and construct new biological parts, devices, and systems. This field is playing a critical role in advancing biotechnology, with applications ranging from the production of biofuels to the development of new medical therapies. Thesis topics could explore the use of synthetic biology in creating bio-based materials, the role of biotechnology in addressing food security challenges, or the ethical considerations of creating artificial life forms. Additionally, students could investigate the potential of synthetic biology to revolutionize the production of pharmaceuticals or the role of bioengineering in developing sustainable agricultural practices.

Future Directions in Science

As science continues to evolve, new frontiers of research are emerging, offering exciting opportunities for students to engage in groundbreaking work. These future directions in science are often interdisciplinary and involve the integration of advanced technologies and methodologies.

• Space Exploration and Astrobiology The exploration of space has always been a frontier for scientific discovery, but recent advancements in technology have accelerated research in this area. With missions to Mars, the search for habitable exoplanets, and the potential for human colonization of other planets, space exploration presents numerous opportunities for scientific research. Thesis topics could focus on the challenges of long-term space travel, the potential for life on other planets, or the development of technologies for sustainable living in space. Additionally, students could explore the role of astrobiology in understanding the origins of life on Earth and the potential for life elsewhere in the universe.
• Environmental Genomics and Ecosystem Monitoring Advances in genomics are enabling scientists to study the genetic makeup of entire ecosystems, providing insights into biodiversity, species interactions, and environmental changes. Environmental genomics, also known as metagenomics, involves the analysis of genetic material recovered directly from environmental samples. Thesis topics could explore the use of metagenomics in monitoring ecosystem health, the role of environmental DNA (eDNA) in detecting species presence, or the potential of genomics to inform conservation efforts. Additionally, students could investigate the impact of environmental stressors such as pollution and climate change on genetic diversity within ecosystems.
• Fusion Energy and the Future of Power Generation Fusion energy has long been considered the “holy grail” of sustainable energy production due to its potential to provide limitless, clean energy. While still in the experimental stage, significant progress has been made in fusion research, particularly with projects such as ITER (International Thermonuclear Experimental Reactor). Thesis topics could focus on the scientific principles behind nuclear fusion, the technological challenges of building fusion reactors, or the potential environmental and economic impacts of fusion energy. Additionally, students could explore the role of fusion energy in transitioning to a carbon-neutral future and its potential to address global energy demands.
• Neuroscience and Brain-Machine Interfaces Advances in neuroscience are providing new insights into the functioning of the brain and the potential for brain-machine interfaces (BMIs) to enhance human capabilities. BMIs involve the direct communication between the brain and external devices, enabling applications such as prosthetics, brain-controlled computers, and even the potential for neural enhancement. Thesis topics could explore the role of BMIs in restoring mobility to individuals with spinal cord injuries, the ethical considerations of neural augmentation, or the potential of BMIs to revolutionize the field of neuroprosthetics. Additionally, students could investigate the challenges of developing BMIs for widespread use and the potential societal implications of neural enhancement.
• Synthetic Food Production and Food Security As the global population grows and the demand for food increases, synthetic food production offers a potential solution to food security challenges. Technologies such as lab-grown meat, plant-based alternatives, and precision fermentation are transforming the food industry. Thesis topics could explore the scientific principles behind synthetic food production, the environmental benefits of alternative proteins, or the potential impact of lab-grown meat on traditional agriculture. Additionally, students could investigate the role of synthetic food in addressing global hunger and the challenges of scaling these technologies for mass production.

The range of science thesis topics is as vast and diverse as the field of science itself. Whether addressing current issues such as climate change and public health, exploring recent trends in artificial intelligence and biotechnology, or delving into the future directions of space exploration and fusion energy, students have the opportunity to engage in research that pushes the boundaries of knowledge and contributes to solving some of the world’s most pressing problems. By selecting a thesis topic that aligns with their interests and passions, students can make meaningful contributions to the scientific community and help shape the future of science and technology.

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Digital Commons @ USF > College of Arts and Sciences > Molecular Biosciences > Theses and Dissertations

Molecular Biosciences Theses and Dissertations

Theses/dissertations from 2024 2024.

Black Holes in TIME: the Effect of GRID Radiation on the Tumor Immune Microenvironment , Rebecca A. Bekker

The Role of L-fucose in Dendritic Cell Antigen Presentation and Polarization , Chase J. Burton

Cornus officinalis extract activates the Keap1/Nrf2 pathway and delays T1D onset in the NOD mouse , Justin D. Fletcher

Androgen Drives Melanoma Invasiveness and Metastatic Spread by Inducing Tumorigenic Fucosylation , Qian Liu

TetR Family Regulator, FarR, Influences Rot-mediated Control of Virulence Factor Expression in Staphylococcus aureus , Julia C. Schumacher

Theses/Dissertations from 2023 2023

Exploring strain variation and bacteriophage predation in the gut microbiome of Ciona robusta , Celine Grace F. Atkinson

Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression , Janine M. DeBlasi

Thermodynamic frustration of TAD2 and PRR contribute to autoinhibition of p53 , Emily Gregory

Utilization of Detonation Nanodiamonds: Nanocarrier for Gene Therapy in Non-Small Cell Lung Cancer , Allan E. Gutierrez

Utilizing neoantigen-specific CD4* T cells and immune checkpoint modulation to advance adoptive cell therapy with tumor-infiltrating lymphocytes for metastatic melanoma patients , Maclean Scott Hall

Role of HLA-DRB1 Fucosylation in Anti-Melanoma Immunity , Daniel K. Lester

Targeting BET Proteins Downregulates miR-33a To Promote Synergy with PIM Inhibitors in CMML , Christopher T. Letson

The Role of the DNA Helicase Rrm3 under Replication Stress , Julius Muellner

Regulated Intramembrane Proteolysis by M82 Peptidases: The Role of PrsS in the Staphylococcus aureus Stress Response , Baylie M. Schott

Histone Deacetylase 8 is a Novel Therapeutic Target for Mantle Cell Lymphoma and Preserves Natural Killer Cell Cytotoxic Function , January M. Watters

Theses/Dissertations from 2022 2022

Ceramide-1-Phosphate: A Novel Regulator of Golgi Fragmentation, Golgi-ER Vesicle Trafficking, and Anaplasma phagocytophilum Pathogenesis , Anika Nayar Ali

Regulation of the Heat Shock Response via Lysine Acetyltransferase CBP-1 and in Neurodegenerative Disease in Caenorhabditis elegans , Lindsey N. Barrett

Establishment of a Melanoma ESC-GEMM Platform and Its Use to Study PTEN Tumor Suppressor Functions , Ilah Bok

Adrenergic Modulation of Precursor Cells of Ovarian Cancer , Sweta Dash

Determining the Role of Dendritic Cells During Response to Treatment with Paclitaxel/Anti-TIM-3 , Alycia Gardner

To be or not to be: A Tale of Staphylococcal GpsB , Lauren R. Hammond

Origin and Epigenetic Regulation of Cutaneous T Cell Lymphoma , Carly M. Harro

Cell-free DNA Methylation Signatures in Cancer Detection and Classification , Jinyong Huang

The Role Of Eicosanoid Metabolism in Mammalian Wound Healing and Inflammation , Kenneth D. Maus

A Holistic Investigation of Acidosis in Breast Cancer , Bryce Ordway

Characterizing the Impact of Postharvest Temperature Stress on Polyphenol Profiles of Red and White-Fruited Strawberry Cultivars , Alyssa N. Smith

Identification of Secondary Structural Elements Contained Within the Intrinsically Disordered N-Terminal Tail of the Bloom’s Syndrome Helicase. , Vivek Somasundaram

Defining the role of Oxidized Mitochondrial DNA in Myelodysplastic Syndromes , Grace Anne Ward

Lord of the Z-rings: Uncovering the Role of MraZ and FtsL in Bacillus subtilis Cell Division , Maria Louise White

Theses/Dissertations from 2021 2021

Multifaceted Approach to Understanding Acinetobacter baumannii Biofilm Formation and Drug Resistance , Jessie L. Allen

Cellular And Molecular Alterations Associated with Ovarian and Renal Cancer Pathophysiology , Ravneet Kaur Chhabra

Ecology and diversity of boletes of the southeastern United States , Arian Farid

CircREV1 Expression in Triple-Negative Breast Cancer , Meagan P. Horton

Microbial Dark Matter: Culturing the Uncultured in Search of Novel Chemotaxonomy , Sarah J. Kennedy

The Multifaceted Role of CCAR-1 in the Alternative Splicing and Germline Regulation in Caenorhabditis elegans , Doreen Ikhuva Lugano

Unraveling the Role of Novel G5 Peptidase Family Proteins in Virulence and Cell Envelope Biogenesis of Staphylococcus aureus , Stephanie M. Marroquin

Cytoplasmic Polyadenylation Element Binding Protein 2 Alternative Splicing Regulates HIF1α During Chronic Hypoxia , Emily M. Mayo

Transcriptomic and Functional Investigation of Bacterial Biofilm Formation , Brooke R. Nemec

A Functional Characterization of the Omega (ω) subunit of RNA Polymerase in Staphylococcus aureus , Shrushti B. Patil

The Role Of Cpeb2 Alternative Splicing In TNBC Metastasis , Shaun C. Stevens

Screening Next-generation Fluorine-19 Probe and Preparation of Yeast-derived G Proteins for GPCR Conformation and Dynamics Study , Wenjie Zhao

Theses/Dissertations from 2020 2020

Understanding the Role of Cereblon in Hematopoiesis Through Structural and Functional Analyses , Afua Adutwumwa Akuffo

To Mid-cell and Beyond: Characterizing the Roles of GpsB and YpsA in Cell Division Regulation in Gram-positive Bacteria , Robert S. Brzozowski

Spatiotemporal Changes of Microbial Community Assemblages and Functions in the Subsurface , Madison C. Davis

New Mechanisms That Regulate DNA Double-Strand Break-Induced Gene Silencing and Genome Integrity , Dante Francis DeAscanis

Regulation of the Heat Shock Response and HSF-1 Nuclear Stress Bodies in C. elegans , Andrew Deonarine

New Mechanisms that Control FACT Histone Chaperone and Transcription-mediated Genome Stability , Angelo Vincenzo de Vivo Diaz

Targeting the ESKAPE Pathogens by Botanical and Microbial Approaches , Emily Dilandro

Succession in native groundwater microbial communities in response to effluent wastewater , Chelsea M. Dinon

Role of ceramide-1 phosphate in regulation of sphingolipid and eicosanoid metabolism in lung epithelial cells , Brittany A. Dudley

Allosteric Control of Proteins: New Methods and Mechanisms , Nalvi Duro

Microbial Community Structures in Three Bahamian Blue Holes , Meghan J. Gordon

A Novel Intramolecular Interaction in P53 , Fan He

The Impact of Myeloid-Mediated Co-Stimulation and Immunosuppression on the Anti-Tumor Efficacy of Adoptive T cell Therapy , Pasquale Patrick Innamarato

Investigating Mechanisms of Immune Suppression Secondary to an Inflammatory Microenvironment , Wendy Michelle Kandell

Posttranslational Modification and Protein Disorder Regulate Protein-Protein Interactions and DNA Binding Specificity of p53 , Robin Levy

Mechanistic and Translational Studies on Skeletal Malignancies , Jeremy McGuire

Novel Long Non-Coding RNA CDLINC Promotes NSCLC Progression , Christina J. Moss

Genome Maintenance Roles of Polycomb Transcriptional Repressors BMI1 and RNF2 , Anthony Richard Sanchez IV

The Ecology and Conservation of an Urban Karst Subterranean Estuary , Robert J. Scharping

Biological and Proteomic Characterization of Cornus officinalis on Human 1.1B4 Pancreatic β Cells: Exploring Use for T1D Interventional Application , Arielle E. Tawfik

Evaluation of Aging and Genetic Mutation Variants on Tauopathy , Amber M. Tetlow

Theses/Dissertations from 2019 2019

Investigating the Proteinaceous Regulome of the Acinetobacter baumannii , Leila G. Casella

Functional Characterization of the Ovarian Tumor Domain Deubiquitinating Enzyme 6B , Jasmin M. D'Andrea

Integrated Molecular Characterization of Lung Adenocarcinoma with Implications for Immunotherapy , Nicholas T. Gimbrone

The Role of Secreted Proteases in Regulating Disease Progression in Staphylococcus aureus , Brittney D. Gimza

Advanced Proteomic and Epigenetic Characterization of Ethanol-Induced Microglial Activation , Jennifer Guergues Guergues

Understanding immunometabolic and suppressive factors that impact cancer development , Rebecca Swearingen Hesterberg

Biochemical and Proteomic Approaches to Determine the Impact Level of Each Step of the Supply Chain on Tomato Fruit Quality , Robert T. Madden

Enhancing Immunotherapeutic Interventions for Treatment of Chronic Lymphocytic Leukemia , Kamira K. Maharaj

Characterization of the Autophagic-Iron Axis in the Pathophysiology of Endometriosis and Epithelial Ovarian Cancers , Stephanie Rockfield

Understanding the Influence of the Cancer Microenvironment on Metabolism and Metastasis , Shonagh Russell

Modeling of Interaction of Ions with Ether- and Ester-linked Phospholipids , Matthew W. Saunders

Novel Insights into the Multifaceted Roles of BLM in the Maintenance of Genome Stability , Vivek M. Shastri

Conserved glycine residues control transient helicity and disorder in the cold regulated protein, Cor15a , Oluwakemi Sowemimo

A Novel Cytokine Response Modulatory Function of MEK Inhibitors Mediates Therapeutic Efficacy , Mengyu Xie

Novel Strategies on Characterizing Biologically Specific Protein-protein Interaction Networks , Bi Zhao

Theses/Dissertations from 2018 2018

Characterization of the Transcriptional Elongation Factor ELL3 in B cells and Its Role in B-cell Lymphoma Proliferation and Survival , Lou-Ella M.m. Alexander

Identification of Regulatory miRNAs Associated with Ethanol-Induced Microglial Activation Using Integrated Proteomic and Transcriptomic Approaches , Brandi Jo Cook

Molecular Phylogenetics of Floridian Boletes , Arian Farid

MYC Distant Enhancers Underlie Ovarian Cancer Susceptibility at the 8q24.21 Locus , Anxhela Gjyshi Gustafson

Quantitative Proteomics to Support Translational Cancer Research , Melissa Hoffman

A Systems Chemical Biology Approach for Dissecting Differential Molecular Mechanisms of Action of Clinical Kinase Inhibitors in Lung Cancer , Natalia Junqueira Sumi

Investigating the Roles of Fucosylation and Calcium Signaling in Melanoma Invasion , Tyler S. Keeley

Synthesis, Oxidation, and Distribution of Polyphenols in Strawberry Fruit During Cold Storage , Katrina E. Kelly

Investigation of Alcohol-Induced Changes in Hepatic Histone Modifications Using Mass Spectrometry Based Proteomics , Crystina Leah Kriss

Off-Target Based Drug Repurposing Using Systems Pharmacology , Brent M. Kuenzi

Investigation of Anemarrhena asphodeloides and its Constituent Timosaponin-AIII as Novel, Naturally Derived Adjunctive Therapeutics for the Treatment of Advanced Pancreatic Cancer , Catherine B. MarElia

The Role of Phosphohistidine Phosphatase 1 in Ethanol-induced Liver Injury , Daniel Richard Martin

Theses/Dissertations from 2017 2017

Changing the Pathobiological Paradigm in Myelodysplastic Syndromes: The NLRP3 Inflammasome Drives the MDS Phenotype , Ashley Basiorka

Modeling of Dynamic Allostery in Proteins Enabled by Machine Learning , Mohsen Botlani-Esfahani

Uncovering Transcriptional Activators and Targets of HSF-1 in Caenorhabditis elegans , Jessica Brunquell

The Role of Sgs1 and Exo1 in the Maintenance of Genome Stability. , Lillian Campos-Doerfler

Mechanisms of IKBKE Activation in Cancer , Sridevi Challa

Discovering Antibacterial and Anti-Resistance Agents Targeting Multi-Drug Resistant ESKAPE Pathogens , Renee Fleeman

Functional Roles of Matrix Metalloproteinases in Bone Metastatic Prostate Cancer , Jeremy S. Frieling

Disorder Levels of c-Myb Transactivation Domain Regulate its Binding Affinity to the KIX Domain of CREB Binding Protein , Anusha Poosapati

Role of Heat Shock Transcription Factor 1 in Ovarian Cancer Epithelial-Mesenchymal Transition and Drug Sensitivity , Chase David Powell

Cell Division Regulation in Staphylococcus aureus , Catherine M. Spanoudis

A Novel Approach to the Discovery of Natural Products From Actinobacteria , Rahmy Tawfik

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Student Research Projects and Theses

Students majoring in Biology have the opportunity to conduct research with our faculty.  For students who qualify, this research often culminates in a senior thesis project which is a requirement for students to graduate with Honors in Biology.

Meet our Current Thesis Students

Tyler allcroft, ’23.

I got into this research because of my interest in how oxidative stress affects biological systems as it has implications in cancer and other diseases. I am interested in oncologic medicine and will apply to medical school this spring.

Alyce Segal, ’23

I got into this work as I wanted to be more involved in the field of ecology. Knowing that the state of our planet is less than ideal, I wanted the research that I was involved in to contribute to a healthier planet in one way or another.

Flynn Gorman, ’23

I have been working in Dr. Toscano’s lab since May of 2021 and in doing so I have been given the amazing opportunity to further my research experience outside of coursework while also having the freedom to design my own experiments, collaborate with my lab mates, and gain experience in writing and preparing my own thesis. Additionally, doing research at Trinity qualified me to apply and be awarded a research fellowship under the National Science Foundation’s REU program in which I studied the reproductive ultrastructure of hydrothermal vent gastropods at the University of Oregon. I hope to continue researching after I graduate in May and apply the skills I have learned at Trinity to new and diverse scientific disciplines in my career!

Julian Marlowe, ’23

I got involved in research during my junior year after taking many courses covering cellular signaling and genetics. These classes were very formative and sparked my interest in the genetic techniques that can be utilized to dissect complex pathways.

Jacob Borgida, ’23

During the summer of 2020, I conducted research on gene-targeted therapies for the repair of the nervous system through a lab at the University of Minnesota Medical School. After completing a genetics course at Trinity in the spring of 2021, I began research at a clinical genetics lab in Boston named Genomes2People. One of their main projects I contributed to was examining the behavioral, economic, and medical impact of genetic sequencing in newborns. Through this research, my interest in genetics spiked and I was able to find a set of disorders that allows me to combine my interest in genetics with cell biology. I plan to pursue medical school after graduating from Trinity in the spring of 2023.

Olivia Pomerleau, ’23

My name is Olivia Pomerleau and I am a thesis student in the biology department. I am currently studying the relationship between the skin microbiome and atopic dermatitis, also known as eczema. More specifically, I am looking at the treatment options for adult-onset atopic dermatitis. I am hypothesizing that adult-onset atopic dermatitis is more of a microbiome dysbiosis issue.

I chose this area of research because my aunt recently was diagnosed with eczema and never had it as a child. I also am interested in going to medical school and hopefully pursuing dermatology. Combining all of this with my interest in microbiology, I found the perfect topic to study. Currently I am also an EMT at Trinity Health of New England. I have found that emergency medicine is quite different from studying skin diseases.

Henry Lagasse, ’23

While looking at molecular data to form a phylogeny is the most concrete way of identifying how species are related to one another, morphological data can provide evidence both for species circumscription as well as the evolution of functional traits. As a result, it is important to be able to combine molecular and morphological evidence in identifying a species.

In my research I am looking at spore perine morphology as a possible new character to be used in the identification of species within the fern genus, Polystichum. Fern spores have an outer layer called the perispore that has different ornamental structures like ridges and perforations that are known to vary interspecifically. I am scoring perine characteristics using SEM (scanning electron microscopy) image and mapping these characters onto a molecular phylogeny of Polystichum in order to reconstruct evolutionary history.

I got into this research due to my interest in plant biology that I gained through taking Plants of New England (BIOL 218), Botany (BIOL 215), and Evolution of plant structures (BIOL 223). Professor Patel is my thesis advisor for this project.