pharmacology phd germany

79 Best universities for Pharmacology in Germany

Updated: February 29, 2024

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Below is a list of best universities in Germany ranked based on their research performance in Pharmacology. A graph of 4.94M citations received by 140K academic papers made by 79 universities in Germany was used to calculate publications' ratings, which then were adjusted for release dates and added to final scores.

We don't distinguish between undergraduate and graduate programs nor do we adjust for current majors offered. You can find information about granted degrees on a university page but always double-check with the university website.

1. Heidelberg University - Germany

For Pharmacology

2. Charite - Medical University of Berlin

3. Goethe University of Frankfurt am Main

4. University of Munich

5. Johannes Gutenberg University Mainz

6. Free University of Berlin

7. Heinrich Heine University of Dusseldorf

8. Hannover Medical School

9. University of Tubingen

10. University of Bonn

11. University of Erlangen Nuremberg

12. University of Freiburg

13. University of Wurzburg

14. University of Hamburg

15. Technical University of Munich

16. University of Gottingen

17. University of Marburg

18. University of Cologne

19. Saarland University

20. University of Munster

21. University of Lubeck

22. Humboldt University of Berlin

23. RWTH Aachen University

24. University of Leipzig

25. Kiel University

26. University of Regensburg

27. Ruhr University Bochum

28. University of Giessen

29. University of Ulm

30. Martin Luther University of Halle-Wittenberg

31. Friedrich Schiller University of Jena

32. University of Duisburg - Essen

33. Dresden University of Technology

34. University of Rostock

35. Otto von Guericke University of Magdeburg

36. University of Veterinary Medicine Hannover

37. University of Greifswald

38. University of Konstanz

39. Braunschweig University of Technology

40. TU Dortmund University

41. University of Hohenheim

42. Witten/Herdecke University

43. Technical University of Kaiserslautern

44. University of Mannheim

45. University of Bremen

46. University of Stuttgart

47. German Sport University Cologne

48. Technical University of Berlin

49. Karlsruhe Institute of Technology

50. University of Bielefeld

51. University of Bayreuth

52. University of Potsdam

53. Leibniz University of Hanover

54. Aachen University of Applied Sciences

55. Carl von Ossietzky University of Oldenburg

56. Darmstadt University of Technology

57. University of Trier

58. Hannover University of Applied Sciences

59. Munich University of the Federal Armed Forces

60. Hamburg University of Technology

61. Osnabruck University

62. University of Wuppertal

63. Jacobs University Bremen

64. Weihenstephan-Triesdorf University of Applied Sciences

65. Mainz University of Applied Sciences

66. University of Bamberg

67. University of Kassel

68. University of Paderborn

69. Biberach University of Applied Sciences

70. Chemnitz University of Technology

71. Fulda University of Applied Sciences

72. University of Augsburg

73. Brandenburg University of Technology Cottbus - Senftenberg

74. Berlin Technical University of Applied Sciences

75. UniveWismar University of Applied Sciences

76. Reutlingen University

77. Ilmenau University of Technology

78. University of Koblenz-Landau

79. University of Applied Sciences Landshut

The best cities to study Pharmacology in Germany based on the number of universities and their ranks are Heidelberg , Berlin , Frankfurt , and Munich .

Medicine subfields in Germany

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Pharmaceutical Sciences

The research in pharmaceutical sciences at the Institute of Pharmacy and Molecular Biotechnology is focused on the development, investigation, and application of drugs and bioactive compounds, as well as on the elucidation of molecular and cellular mechanisms of action. It integrates experimental approaches of chemistry, molecular and cellular biology, pharmacology, bioinformatics, pharmaceutics and clinical pharmacy. Main research areas of our institute include nucleic acids as tools and drug targets, development of new antiinfective drugs, research on neurodegenerative diseases as well as drug targeting and transport.

Supervising professors

Prof. dr. gert fricker, prof. dr. andres jäschke, prof. dr. christian klein, prof. dr. walter mier, prof. dr. ulrike müller, prof. dr. dominik niopek, prof. dr. philipp uhl, prof. dr. rebecca wade, prof. dr. stefan wölfl.

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3255 Study programs

Study Pharmacology in Germany: 24 Universities with 31 English Degree Programs

All important info for international students in germany (2024/2025).

Pharmacology stands at the crossroads of science and medicine, delving deep into the actions and effects of drugs on biological systems. This domain explores the therapeutic benefits and potential risks of drugs, shedding light on drug interactions, mechanisms of action, and potential side effects. Drawing from biology, chemistry, and physiology, students in pharmacology gain profound insights into drug discovery, testing, and regulatory aspects. As they venture into the world of Pharmacology, learners are equipped to design and evaluate new drugs, ensuring efficacy and safety. Upon graduation, they can thrive as clinical pharmacologists, research scientists, or regulatory affairs specialists, shaping the future of medicine.

Study Programs in English

Universities

Universities in International Rankings

€ 0 (23 programs for EU citizens, 16 programs for Non-EU citizens)

€ 10,000 per semester (1 program for EU citizens/Non-EU)

Winter Semester

between September 30 and September 15

Summer Semester

between September 30 and September 01

Top-ranked German Universities in Pharmacology

public University

No. of Students: approx. 8,900 students

Program Fees: € 2,500 (per semester)

No. of Students: approx. 36,000 students

Program Fees: € 2,250 - € 2,500 (per semester)

No. of Students: approx. 38,000 students

No. of Students: approx. 27,000 students

Program Fees: € 0 - € 1,500 (per semester)

Tuition Fees

3 english degree programs for pharmacology in germany.

Friedrich Schiller University Jena Jena

Ehealth and communication.

University of Göttingen Göttingen

Chemistry [english & german track].

Cardiovascular Science

Application Deadlines

Winter Semester 2024/2025

Summer Semester 2025

Winter Semester 2025/2026

Open Programs

13 programs

28 programs

Application Modes

Application process, molecular medicine.

Chemistry [English track]

University of Freiburg Freiburg im Breisgau

Biomedical sciences.

TOEFL Scores

Cambridge Levels

5 (1 program )

72 (3 programs )

B2 First (FCE) (7 programs )

7 (6 programs )

95 (6 programs )

C2 Proficiency (CPE) (8 programs )

Hochschule Bonn-Rhein-Sieg Rheinbach

Applied biology.

Hochschule Fresenius - University of Applied Sciences Wiesbaden

Pharmaceutical medicine.

Hamburg University of Applied Sciences Hamburg

Pharmaceutical biotechnology.

2-6 semesters

→ View all programs with online courses

Master of Science

Bachelor of Science

Winter intake

Summer intake

Winter & Summer intake

List of all German Universities offering English-taught Study Programs in Pharmacology

Anhalt University of Applied Sciences

Program Fees: € 1,160

M.Sc. (Master of Science)

Charité - Universitätsmedizin Berlin

Program Fees: € 2,500

Coburg University

Program Fees: € 0

Constructor University

Program Fees: € 10,000

B.Sc. (Bachelor of Science)

Freie Universität Berlin

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Let’s shape the future - University of AntwerpThe University of Antwerp is a dynamic, forward-thinking, university. We offer an innovative academic education to more than 20000 students, conduct pi...

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The doctoral program Clinical Pharmacy is an interdisciplinary institution at the university hospital of LMU Munich. Research projects of this program intend to improve safety in drug therapy and aim to increase patient safety for various medical conditions. To create a scientific data base in the field of applied clinical pharmacy in Germany is a further objective. In a stimulating research environment doctoral projects are supervised by interprofessional teams each consisting of a pharmacist and a medical doctor. This way scientific and clinical resources and support are ensured. Active exchange during regular seminars, workshops and further occasions with fellow doctoral candidates, supervisors and other scientists of the excellent research environment in Munich complement this program.

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Each of our structured doctoral programs offers a comprehensive and cross-disciplinary curriculum designed to help you realize your full potential and prepare for a successful career. The programs include innovative, personalized advising with regular progress checks, as well as extensive opportunities to broaden your research network and connect with peers in your field.

The University of Bonn offers a wide range of funding opportunities, which have been summarized for you on this page, divided into the following categories:

Bonn International Graduate Schools (BIGS)

Phd programs within our cluster of excellence.

• Structured Doctoral Programs by Discipline 

Third-Party Funded Programs

Doctoral education at the highest level: BIGS enable doctoral studies in outstanding research contexts with attractive international collaborations and a qualification program tailored to the needs of graduate students.

Located at the Hausdorff Center for Mathematics and supported by Germany’s Excellence Initiative, BIGS-M  is home to all of the University’s doctoral candidates in mathematics and contributes to Bonn’s excellent international reputation in the field.

BGSE offers a structured program that is tailored to the needs of doctoral candidates, including an internationally recognized research network.

Supported by Germany’s Excellence Initiative and jointly administered by the renowned Physics Institutes at the Universities of Bonn and Cologne, BCGS  offers doctoral studies through an integrated honors program.

Home to an international community of talented biomedical scientists, BIGS DrugS 6 6 is the hub for doctoral candidates from pharma research institutes within the University’s Faculty of Mathematics and Natural Sciences and Faculty of Medicine.

BIGS-OAS offers a wide range of courses within a research context, focused on the cultures and societies of Asia and Asia Minor.

BIGS Neuroscience provides a top-level, internationally competitive program in this rapidly growing field.

BIGS CPS's interdisciplinary approach combines medical, agricultural and pharmaceutical research.

BIGS Chemistry 10 doctoral candidates enjoy an exceptional and ambitious program covering all fields of chemistry.

This three-year doctoral program  is offered in conjunction with the University’s ImmunoSensation Cluster, which is funded by Germany’s Excellence Initiative.

Part of the University of Bonn’s Center for Development Research, BIGS-DR   trains students for an international career in development cooperation, policy or research through a combination of academic study and intensive tutorship.

The BIGS Land and Food combines the research at the agricultural Faculty with an interdisciplinary study program.

BIGS-LIMES offers a graduate program for doctoral students in Bonn specializing in biochemistry, life sciences and biomedicine.

Clusters of Excellence stand for international and interdisciplinary elite research and offer young scientists excellent funding and career conditions. The University of Bonn currently has six clusters of excellence, more than any other university in Germany, and thus opens up a broad spectrum of possible research topics to doctoral candidates. Here you will find an overview of the university's clusters of excellence.

PhD Programs within our Excellence Cluster

The goal of the Hausdorff Center of Mathematics is to identify and address mathematical challenges of the 21st century, to advance groundbreaking fundamental mathematical research worldwide, and to develop the mathematical methods and tools required by science and society.

Part of the Hausdorff Center is also a graduate school: The Bonn International Graduate School of Mathematics (BIGS-M) hosts all doctoral students of mathematics and contributes to the outstanding international reputation of the university in this field. The duration of the program is usually 3 years, and the doctorate (Dr. rer nat.) can be earned as a degree.

More information: https://www.bigs-math.uni-bonn.de/de/studies/ 14 15 15

ImmunoSensation2 aims to continue the success story of the existing ImmunoSensation cluster. While the emphasis so far has been on fundamental research in particular of the innate immune system, now the mechanisms of immune intelligence are to be uncovered, i.e. the question of how the body succeeds in adapting immune responses to specific situations and then remembers this in order to be optimally prepared for similar challenges in the future. The cluster's graduate school, the Bonn International Graduate School Immunosciences and Infection offers a structured, three-year doctoral program.

You can find further information about this program here: 

https://www.immunosensation.de/opportunities/young-scientists

Until today, dependency studies has almost exclusively dealt with slavery on the American continent or in antiquity. The Cluster of Excellence "Bonn Center for Dependency and Slavery Studies (BCDSS)" aims to broaden this perspective in terms of content, space and time. Within the framework of the cluster, a structured doctoral program with a duration of 4 years is offered.

Further information can be found at:  https://www.dependency.uni-bonn.de/en 15 16

Over the last few decades, computer hardware has become smaller and smaller, but their technology remains more or less the same. Slowly, this development is reaching its limits.Thus, we need new technologies that satisfy our growing hunger for even more powerful hardware.

Quantum physics could be a solution.

Together with the University of Cologne and the RWTH Aachen, Bonn researchers want to work on making this new technology usable. To achieve this, quantum bits or even qubits - the quantum counterpart to our previous bits - quantum communication channels that build networks and error correction methods have to be explored from the ground up. As part of the Excellence Initiative, the Bonn-Cologne Graduate School of Physics and Astronomy (BCGS) offers a doctoral program with an integrated honors program.

Further information can be found at:  http://www.gradschool.physics.uni-bonn.de/. 4 4

The ECONtribute researches the functioning of markets as well as reasons for their failure. In doing so, the cluster goes beyond traditional analyses by systematically combining model-based theoretical approaches and behavioral explanatory models while incorporating legal and political frameworks. Within the cluster, the Bonn Graduate School of Economics (BGSE) offers doctoral students a tailored structured doctoral program that includes an internationally recognized research network.

Further information can be found at:  https://www.bgse.uni-bonn.de. 3 3

Increasing agricultural production despite limited land while reducing the ecological footprint of agriculture - this is one of the challenges of our time. For this reason, the University of Bonn and Forschungszentrum Jülich are jointly developing methods and new technologies to observe, analyze, better understand and more specifically treat plants. The cluster's graduate school, the Theodor Brinkmann Graduate School, offers an interdisciplinary study program to master's students and doctoral candidates at the Faculty of Agriculture.

More information: https://www.phenorob.de/ .

The Third-Party Funded Programs at the University of Bonn offer structured doctoral studies on selected research topics. They enable close networking among doctoral students conducting research on related topics.

Bonn International Graduate School of Mathematics (BIGS-M) 2 17 18 18 Located at the Hausdorff Center for Mathematics, BIGS-M provides an umbrella for all Bonn PhD students in mathematics. Thus, the BIGS-M contributes to the excellent national and international reputation of mathematics at Bonn.

Bonn International Graduate School Immunosciences and Infection The BIGS Immunosciences and Infection is a structured 3-year PhD program in conjunction with the ImmunoSensation Cluster/Bonn. The ImmunoSensation Cluster is part of the Excellence Strategy.

DFG Research Training Group "Gegenwart/Literatur. Geschichte, Theorie und Praxeologie eines Verhältnisses" (GRK 2291) [only in German] The Research Training group supported by the DFG  aims at the exploration and analysis of the constitutive dimensions of the concept of contemporary literature.  

DFG international Research Training Group "Myeloid antigen presenting cells and the induction of adaptive immunity" GRK (2168) 19 19 19 19 The DFG-funded project is a cooperation of the University of Bonn and the University of Melbourne. The principal research focus is the intersection between innate and adaptive immunity in the context of infection.

DFG Research Training Group "Template-designed Organic Electronics (TIDE)" (GRK 2591) 21 21 21 The Graduate Program 'Template-Designed Optoelectronic Devices' (TIDE) aims to provide comprehensive doctoral education in the field of Organic Electronics (OE) to meet the requirements of highly qualified and multidisciplinary professionals. 

DFG Research Training Group "Tools and Drugs of the Future - Innovative Methods and New Modalities in Medicinal Chemistry" (GRK 2873) The goal of the RTG " Tools and Drugs of the Future" is to modernize medicinal chemistry and train a new generation of medicinal chemists and researchers at the interface with interconnected disciplines. In addition, the projects are intended to contribute to the development of new drug substances.

Integrated Research Training Group at the DFG Collaborative Research Centre "Synaptic Micronetworks in Health and Disease" (SFB 1089) 22 22 27 27 Located at the newly inaugurated SFB 1089 on neuronal networks, the Integrated Research Training Group offers a structured graduate program for all doctoral researchers at the Centre.

Integrated Research Training Group at theDFG Collaborative Research Centre "Future Rural Africa" (SFB/TRR 228) The integrated research group is investigating the relationship between land use change and shaping the future in rural Africa in a total of 14 subprojects.

Integrated Research Training Group at the DFG Collaborative Research Centre "Open System Control of Atomic and Photonic Matter" (SFB/TRR 185) 24 The collaborative research centre Oscar will explore the physics of open systems.

Integrated Research Training Group at the DFG Collaborative Research Centre "Aortic Diseases" (SFB/TRR 259) 25 The aim of this research initiative is to better understand the molecular and cellular mechanisms of resident and non-resident cells in aortic diseases.

Integrated Research Training Group at the DFG Collaborative Research Centre "Regional Climate Change: Disentangling the Role of Land Use and Water Management" (SFB 1502) The SFB combines the strengths of the University of Bonn and its project partners to answer one of the most difficult questions in understanding climate change.

Integrated Research Training Group at the DFG Collaborative Research Centre "Brown and Beige Fat - Organ Crosstalk, Signaling and Energetics (BATenergy)" (SFB/TRR 333) The CRC investigates metabolism/diabetes and focusses on brown adipose tissue. 

One Health and Urban Transformation

The NRW Forschungskolleg One Health and Urban Transformation is a transdisciplinary graduate school that aims to find interventions to achieve optimal health for humans, animals, plants and the environment with a special focus on developments in NRW, Saõ Paulo, Accra and Ahmedabad.

International Max Planck Research School Moduli Spaces 27 27 In cooperation with the University of Bonn, the renowned Bonn Max-Planck-Institute for Mathematics offers a PhD program with a special focus on the study of moduli.

International Max Planck Research School for Astronomy and Astrophysics 28 28 In cooperation between the Max-Planck Institute for Radio Astronomy and the Universities of Bonn and of Cologne, the Research School facilitates 3 years of PhD studies with a curriculum tailored to the individual student.

International Max Planck Research School for Brain and Behavior 29 The IMPRS for Brain & Behavior is a cooperation between the Max Planck Institute for Neurobiology of Behavior - caesar, the University of Bonn and the German Center for Neurodegenerative Diseases (DZNE) in Bonn

International Max Planck Research School - Recharge IMPRS-RECHARGE focuses on interdisciplinary research between chemistry and physics with an emphasis on catalytic mechanisms, physical-chemical analysis and energy topics. Scientific challenges shall be looked at from different angles. Furthermore the combination of theory and practice is a vital aim of the IMPRS-RECHARGE.

Marie Skłodowska-Curie Innovative Training Network "Macro and Microplastic in Agricultural Soil Systems“ (SOPLAS) The SOPLAS project will assemble a multidisciplinary team to study the nexus of plastic–agriculture–soil. It will also train a new generation of leading experts. The project aims to identify the plastic cycle within agricultural soil systems and support the development of environmental policies related to mitigating the impact of plastics. The findings will advance our knowledge about the sustainable use of plastics in European agriculture.

Marie Skłodowska-Curie Innovative Training Network "Early Stage Researchers EDUCational Program on Factor VIII Immunogenicity“ (EDUC8 ) 32 37 The EDUC8 program is a multidisciplinary training program with exposure of the enrolled ESRs to a core common educational package and development of individual PhD researchprojects dedicated to decreasing the societal burden associated with the development of anti-FVIII antibodies in Europe.

Tools4Teams - "Research Training to Design and Implement Tools Supporting Safe Teamwork in Healthcare"

The Tools4Teams research project will prepare the next generation of teamwork experts to contribute new insights and smart technologies for safe and effective care. Tools4Teams brings together expertise from social and technical sciences, human-centered design, education, and clinical specialties.

Trinational Graduate College "Mass and Integration in Antique Societies" [in German/French] Supported by the Deutsch-Französische Hochschule since 2011, the tri-national Graduate School in Ancient History offers curriculum events in Bonn, Berne, and Strasbourg.

Structured Doctoral Programs by Discipline

Find the right structured doctoral program at the University of Bonn in your discipline here:

• Cross-Disciplinary Options
• Medicine and Life Sciences
• Mathematics and Natural Sciences
• Agriculture

Faculties at the University of Bonn work together to design interdisciplinary programs that combine key perspectives and offer unique insights.

Cross-Disciplinary Programs

Bonn International Graduate School for Development Research (BIGS-DR) 42 Unique in Europe, BIGS-DR links perspectives from the Faculties of Philosophy, Agriculture, and Law and Economics – with an international focus.

Bonn International Graduate School of Neuroscience (BIGS Neuroscience) 8 8 A collaboration between the University’s Faculty of Medicine and Faculty of Mathematics and Natural Sciences, as well as external partners, BIGS Neuroscience offers a medical program alongside five research areas in medicine.

SciMed Doctoral College 43 42 The Doctoral College offers scientific training for students in medicine and dental medicine, leading to a dual Dr. med. and Dr. med. dent. degree.

Researchers at the University of Bonn explore a wide variety of issues in economics, including game theory, applied microeconomics, monetary and international macroeconomics, contract theory, labor economics and finance.

Economics Programs

Bonn Graduate School of Economics (BGSE) BGSE offers a structured program that is tailored to the needs of doctoral candidates, including an internationally recognized research network.

Law Programs

Graduate School of Law and Political Science Department of Law The Graduate School of the Faculty of Law and Political Science was founded in the summer semester of 2018 and supports the doctoral students in preparing their doctoral studies.

The University of Bonn’s Faculty of Medicine offers doctoral programs in medical biochemistry, neurosciences and pharmacology. With the exception of the SciMed Doctoral College, all programs are administered in cooperation with the University’s Faculty of Mathematics and Natural Sciences.

Cross-Disciplinary Program

SciMed Doctoral College The Doctoral College offers scientific training for students in medicine and dental medicine, leading to a dual Dr. med. and Dr. med. dent. degree.

Neuroscience

Bonn International Graduate School of Neuroscience (BIGS Neuroscience) BIGS Neuroscience provides a top-level, internationally competitive program in this rapidly growing field.

Synaptic Micronetworks in Health and Disease (SFB 1089) Supported by the German Research Foundation (Deutsche Forschungsgemeinschaft – DFG) collaborative research centers, this integrated research training group works to identify fundamental rules that govern neuronal behavior at the network level and translate network dynamics to mammalian and human behavior.

International Max Planck Research School for Brain and Behavior A joint venture of the University of Bonn, the Max-Planck-associated Center of Advanced European Studies and Research, the Max Planck Florida Institute for Neuroscience, and Florida Atlantic University, this graduate school offers a complete doctoral and research program in the neurosciences.

Pharma Research

Bonn International Graduate School of Drug Sciences (BIGS DrugS) Home to an international community of talented biomedical scientists, BIGS DrugS is the hub for doctoral candidates from pharma research institutes within the University’s Faculty of Mathematics and Natural Sciences and Faculty of Medicine.

Bonn International Graduate School of Immunosciences and Infection

This three-year doctoral program is offered in conjunction with the University's ImmunoSensation Cluster , which is funded by Germany’s Excellence Initiative.

DFG Research Training Group "Myeloid antigen presenting cells and the induction of adaptive immunity" GRK (2168) The DFG-funded project is a cooperation of the University of Bonn and the University of Melbourne.

At the University of Bonn’s Faculty of Arts, you’ll find a highly international environment with students and researchers in a wide range of fields.

German Studies, Comparative Literature and Culture 

Structured Doctoral Program in German Studies (SPP) [website in German] Taught in German, the SPP supports doctoral candidates’ initiatives within the Institute for German, Comparative Literature and Cultural Studies.

German-Italian Doctoral College [website in German] Taught in German, this three-year grant program provides structured doctoral studies for researchers in German and Italian, with time in both Bonn and Florence.

History and Ancient History 

Mass and Integration in Antique Societies [website in German and French] Supported by Franco-German University and taught in German and French, this trinational doctoral program includes study in Bonn; Berne, Switzerland; and Strasbourg, France.

Oriental and Asian Studies Bonn

International Graduate School of Oriental and Asian Studies (BIGS-OAS) BIGS-OAS offers a wide range of courses within a research context, focused on the cultures and societies of Asia and Asia Minor.

Romance Studies

Italian Studies [website in German and Italian] Offered in cooperation with the Universities of Florence and Paris-Sorbonne IV, this trinational doctoral program is taught in German and Italian.

Structured DPhil program at the Faculty of Arts The program supports qualified doctoral candidates from all disciplines in their doctoral projects. It provides the opportunity for networking, interdisciplinary exchange in diverse social sciences and humanities subjects, progress monitoring and financial support for travel, workshops or research funding as part of the doctorate.

European Founding Myths in Literature, Arts and Music [website in German, French and Italian] This trinational program is jointly organized by the Universities of Bonn, Florence and Paris-Sorbonne IV and taught in German, French and Italian.

Bonn International Graduate School for Development Research (BIGS-DR) Part of the University of Bonn’s Center for Development Research, BIGS-DR trains students for an international career in development cooperation, policy or research through a combination of academic study and intensive tutorship.

The University’s Faculty of Mathematics and Natural Sciences offers numerous externally funded doctoral programs in areas including mathematics and informatics, physics, biology, pharmacology and molecular biomedicine.

Programs in neuroscience, pharma research, immunoscience, and infection and molecular biomedicine are offered in cooperation with the Faculty of Medicine.

Mathematics

Bonn International Graduate School of Mathematics (BIGS-M) 2 2 Located at the Hausdorff Center for Mathematics, BIGS-M is home to all of the University’s doctoral candidates in mathematics and contributes to Bonn’s excellent international reputation in the field.

International Max Planck Research School on Moduli Spaces 53 53 This program includes courses, seminars and activities focused on the geometric spaces whose points represent fixed algebro-geometric objects (or isomorphism classes of such objects).

Physics und Astronomy

Bonn-Cologne Graduate School of Physics and Astronomy (BCGS) 4 4 Supported by Germany’s Excellence Initiative and jointly administered by the renowned Physics Institutes at the Universities of Bonn and Cologne, BCGS offers doctoral studies through an integrated honors program.

International Max Planck Research School of Astronomy and Astrophysics 55 55 This program offers a broad spectrum of topics in observational and theoretical galactic and extragalactic astrophysics, observational and theoretical cosmology, and fundamental physics – using astronomical tools and instrumentation.

Leibniz Graduate School on Genomic Biodiversity Research Based at Bonn’s Alexander Koenig Research Museum, this school is focused primarily on insect genome evolution.

Bonn International Graduate School of Chemistry (BIGS Chemistry) 57 57 BIGS Chemistry offers an internationally competitive doctoral program and opportunities to perform cutting-edge research.

Neurosciences

Bonn International Graduate School of Neuroscience (BIGS Neuroscience) 8 8 BIGS Neuroscience provides a top-level, internationally competitive program in this rapidly growing field.

Synaptic Micronetworks in Health and Disease (SFB 1089) 22 22 Supported by DFG collaborative research centers, this integrated research training group works to identify fundamental rules that govern neuronal behavior at the network level and translate network dynamics to mammalian and human behavior.

International Max Planck Research School for Brain and Behavior 29 29 The IMPRS for Brain & Behavior is a cooperation between the Max Planck Institute for Neurobiology of Behavior - caesar, the University of Bonn and the German Center for Neurodegenerative Diseases (DZNE) in Bonn.

Bonn International Graduate School of Drug Sciences (BIGS DrugS) 6 6 Home to an international community of talented biomedical scientists, BIGS DrugS is the hub for doctoral candidates from pharma research institutes within the University’s Faculty of Mathematics and Natural Sciences and Faculty of Medicine.

BIGS Immunoscience and Infection A structured, three-year doctoral program, IITB is offered in conjunction with the ImmunoSensation Cluster at the University of Bonn.

Doctoral candidates in the field of agriculture may choose to study through the Faculty of Agriculture’s Theodor Brinkmann Graduate School or earn their degree through the University of Bonn’s Center for Development Research.

Agriculture Programs

Bonn International Graduate School for Land and Food (BIGS Land and Food)  Founded in 2008, the Brinkmann School is home to master's and doctoral candidates in the Faculty of Agriculture, combining research with an interdisciplinary study program.

Bonn International Graduate School for Development Research (BIGS-DR) 12 Part of the University of Bonn’s Center for Development Research 59 , BIGS-DR trains researchers for an international career in development cooperation, policy or research through a combination of academic study and intensive tutorship.

Dr. Robert Radu

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• Family Health Center

Sachin A. Gupte, M.D., Ph.D.

• [email protected]
• (914) 594-3739
• (914) 594-4126

Sachin Gupte, M.D., Ph.D., has more than 25 years of education in medicine and the basic sciences. His formal training in cardiovascular medicine and vascular physiology/biology as well as his expertise in redox signaling have prepared him to generate novel hypotheses with immediate translational relevance and to motivate, instruct, and graduate students and fellows. Dr. Gupte has trained more than 29 graduate students and post-doctoral fellows who have successfully pursued careers in research, academia, the pharma industry and/or clinical practice.

• Ph.D., Physiology, Juntendo University School of Medicine

The focus of the ongoing studies in Dr. Gupte's laboratory is elucidating the role of glucose-6-phosphate dehydrogenase-derived NADPH in regulating vascular function (mechanics) and the vessel wall structure. In that context, the lab studies regulation of epigenomic (genes) and phenomic modifications of vascular smooth muscle cell by glucose-6-phosphate dehydrogenase-dependent redox signaling in a variety of in vitro and in vivo systems using state-of-the-art tools in next generation sequencing, molecular biology, and physiology. Another major project that his lab is involved in is to model the human G6PD variants in cell culture and animal models using the revolutionary CRISPR-Cas9 system of genome editing to study their role in regulation of cardiovascular function. At present, his lab is actively elucidating the cellular mechanism(s) through which glucose-6-phosphate dehydrogenase-dependent pyridine nucleotide signaling regulate vascular smooth muscle cell phenotype in normal and disease conditions such as pulmonary hypertension (PH), metabolic syndrome-associated coronary artery disease (MS-CAD) and heart failure.

Particularly, Dr. Gupte's lab is examining the role of pyridine nucleotide signaling in regulating extracellular matrix remodeling and autophagic or apoptotic death of cardiomyocytes during the development of PAH and MS-CAD. Overall, the aim will be to study the metabolic adaptation-cardiovascular function relationship using biochemical, molecular, pharmacological and genetic approaches in novel animal models and in vitro systems that mimic human diseases and to explore novel therapies for PAH and MS-CAD.

Publications

• Matsumura S, Signoretti C, Fatehi S, et. al. "Loss-of-function G6PD variant moderated high-fat diet-induced obesity, adipocyte hypertrophy, and fatty liver in male rats." The Journal of biological chemistry , 300(7), (2024) 107460. doi: 10.1016/j.jbc.2024.107460
• Signoretti C, Gupte SA. "G6PD Orchestrates Genome-Wide DNA Methylation and Gene Expression in the Vascular Wall." International journal of molecular sciences , 24(23), (2023) . doi: 10.3390/ijms242316727
• Krajnik A, Nimmer E, Brazzo JA 3rd, et. al. "Survivin regulates intracellular stiffness and extracellular matrix production in vascular smooth muscle cells." APL bioengineering , 7(4), (2023) 046104. doi: 10.1063/5.0157549
• D'Addario CA, Matsumura S, Kitagawa A, et. al. "Global and endothelial G-protein coupled receptor 75 (GPR75) knockout relaxes pulmonary artery and mitigates hypoxia-induced pulmonary hypertension." Vascular pharmacology , 153(), (2023) 107235. doi: 10.1016/j.vph.2023.107235
• Gupte SA, Bakshi CS, Blackham E, et. al. "The severity of SARS-CoV-2 infection in K18-hACE2 mice is attenuated by a novel steroid-derivative in a gender-specific manner." British journal of pharmacology , 180(20), (2023) 2677-2693. doi: 10.1111/bph.16155
• Signoretti C, Gupte SA. "Studies in CRISPR-generated Mediterranean G6PD variant rats reveal G6PD orchestrates genome-wide DNA methylation and gene expression in vascular wall." bioRxiv : the preprint server for biology , (), (2023) . pii: 2023.03.06.531429. doi: 10.1101/2023.03.06.531429
• Jacob C, Kitagawa A, Signoretti C, et. al. "Mediterranean G6PD variant mitigates expression of DNA methyltransferases and right heart pressure in experimental model of pulmonary hypertension." The Journal of biological chemistry , 298(12), (2022) 102691. doi: 10.1016/j.jbc.2022.102691

Recent Presentations

• CRISPR-Cas9 editing in rats reveal the role of G6PD and NADPH redox in regulating epigenetics of VSMC and vascular biology, Augusta University, GA, United States of America. (08/2020).
• G6PD and Vascular Diseases, University of Rochester, NY, United States of America. (01/2019).
• G6PD and Pulmonary Hypertension, University of Colorado Health Science Center, CO, United States of America. (04/2018).
• Cyp2c44: Stem Cells and Vascular Inflammation/Pathology, The 17th International Winter Eicosanoid Conference, MD, March 11-13, 2018.

Professional Service

Peer Review (Journal Review):

• 2018-Present   Journal of Vascular Research
• 2018-Present   Vascular Pharmacology
• 2017-Present   Hypertension
• 2011-Present   FEBS letter
• 2011-Present   Tumor Biology
• 2011-Present   Biochmie
• 2011-Present   Food and Chemical Toxicology
• 2009-Present   Free Radical Biology & Medicine
• 2009-Present   BBA
• 2008-Present   Antioxidant & Redox Signaling
• 2008-Present   JBC
• 2007-Present   Diabetes; Diabetologia
• 2007-Present   Annals of Thoracic Surgery
• 2006-Present   European Journal of Pharmacology
• 2006-Present   Biochemical Pharmacology
• 2005-Present   FASEB Journal
• 2005-Present   Experimental Cell Medicine
• 2005-Present   Journal of American Society of Nephrology
• 2004-Present   American Journal of Hypertension
• 2004-Present   Journal of Molecular and Cellular Cardiology
• 2004-Present   Journal of Post Graduate Medicine
• 2002-Present   American Journal of Physiology (Heart & Circulation)

Memberships and Affiliations

• Editorial Board Member, American Journal of Physiology (Heart and Circulation), 2005-2020
• Ad hoc member, French Health Ministry, Review Committee, 2019

Teaching Responsibilities

• Cardiovascular and Respiratory Pharmacology/Medicine

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Jeff Wilson MD, PhD, and Corinne Keet, MD, PhD, Were Awarded a $4.1 Million Multi-PI Grant to Study Food Allergens’ Potential Association with Cardiovascular Disease

September 17, 2024 by [email protected]

(From left) Jeff Wilson MD, PhD, University of Virginia, and Corinne Keet, MD, PhD, University of North Carolina

Jeff Wilson MD, PhD, an assistant professor in the UVA Department of Medicine Division of Asthma, Allergy and Immunology, and Corinne Keet, MD, PhD, from the University of North Carolina, were awarded a $4.1 million multi-PI grant from the National Institutes of Health (NIH) to study common food allergens and their potential association with cardiovascular disease.

Food allergies that result in allergic symptoms, such as hives, swelling or anaphylaxis, are relatively uncommon in adults. However, nearly 1 in 5 adults are ‘silently’ producing IgE antibodies to food allergens without showing any overt symptoms. Recent work by Dr. Wilson and colleagues discovered a previously unrecognized link between IgE antibodies to cow’s milk and other common food allergens and an increased risk of cardiovascular mortality. This association was found by measuring antibodies in banked blood samples from over 5,000 adults who were followed longitudinally for about 15 years. The strength of the relationship with cardiovascular mortality was similar to well known risk factors for heart disease, including smoking, diabetes and hypertension and was most pronounced in those who ate the foods that were targeted by their IgE antibodies. The finding suggests an opportunity for precision nutritional prevention of cardiovascular disease and was recently covered by 125 new outlets, including U.S. News and World Report.

The new NIH funding allocates $1.7 million of the award to support Dr. Wilson’s work at UVA as he takes the next critical steps to understanding the relationship between food specific IgE and atherosclerotic plaque resulting in cardiovascular disease. Dr. Wilson’s research is also supported by a UVA Strategic Investment Fund Prominence to Preeminence Award: Immunology, Imaging and Informatics for Precision ImmunoMedicine ( iPRIME) , which provides investigators an ecosystem of support personnel — from the clinical side of consenting patients and reading complex imaging to banking the high-quality samples at the bench. Over 600 samples from the Coronary Assesssment in VA (CAVA) cohort will be used to examine the relationship between IgE to food allergens and atherosclerotic plaque.

Additional UVA collaborators on this project include Coleen McNamara, MD, Todd Villines, MD, Ani Manichaikul, PhD, and Thomas Platts-Mills, MD.

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