research plan biology

Write Your Research Plan

In this part, we give you detailed information about writing an effective Research Plan. We start with the importance and parameters of significance and innovation.

We then discuss how to focus the Research Plan, relying on the iterative process described in the Iterative Approach to Application Planning Checklist shown at Draft Specific Aims  and give you advice for filling out the forms.

You'll also learn the importance of having a well-organized, visually appealing application that avoids common missteps and the importance of preparing your just-in-time information early.

While this document is geared toward the basic research project grant, the R01, much of it is useful for other grant types.

Table of Contents

Research plan overview and your approach, craft a title, explain your aims, research strategy instructions, advice for a successful research strategy, graphics and video, significance, innovation, and approach, tracking for your budget, preliminary studies or progress report, referencing publications, review and finalize your research plan, abstract and narrative.

Your application's Research Plan has two sections:

• Specific Aims —a one-page statement of your objectives for the project.
• Research Strategy —a description of the rationale for your research and your experiments in 12 pages for an R01.

In your Specific Aims, you note the significance and innovation of your research; then list your two to three concrete objectives, your aims.

Your Research Strategy is the nuts and bolts of your application, where you describe your research rationale and the experiments you will conduct to accomplish each aim. Though how you organize it is largely up to you, NIH expects you to follow these guidelines.

• Organize using bold headers or an outline or numbering system—or both—that you use consistently throughout.
• Start each section with the appropriate header: Significance, Innovation, or Approach.
• Organize the Approach section around your Specific Aims.

Format of Your Research Plan

To write the Research Plan, you don't need the application forms. Write the text in your word processor, turn it into a PDF file, and upload it into the application form when it's final.

Because NIH may return your application if it doesn't meet all requirements, be sure to follow the rules for font, page limits, and more. Read the instructions at NIH’s Format Attachments .

For an R01, the Research Strategy can be up to 12 pages, plus one page for Specific Aims. Don't pad other sections with information that belongs in the Research Plan. NIH is on the lookout and may return your application to you if you try to evade page limits.

Follow Examples

As you read this page, look at our Sample Applications and More  to see some of the different strategies successful PIs use to create an outstanding Research Plan.

Keeping It All In Sync

Writing in a logical sequence will save you time.

Information you put in the Research Plan affects just about every other application part. You'll need to keep everything in sync as your plans evolve during the writing phase.

It's best to consider your writing as an iterative process. As you develop and finalize your experiments, you will go back and check other parts of the application to make sure everything is in sync: the "who, what, when, where, and how (much money)" as well as look again at the scope of your plans.

In that vein, writing in a logical sequence is a good approach that will save you time. We suggest proceeding in the following order:

• Create a provisional title.
• Write a draft of your Specific Aims.
• Start with your Significance and Innovation sections.
• Then draft the Approach section considering the personnel and skills you'll need for each step.
• Evaluate your Specific Aims and methods in light of your expected budget (for a new PI, it should be modest, probably under the $250,000 for NIH's modular budget).
• As you design experiments, reevaluate your hypothesis, aims, and title to make sure they still reflect your plans.
• Prepare your Abstract (a summary of your Specific Aims).
• Complete the other forms.

Even the smaller sections of your application need to be well-organized and readable so reviewers can readily grasp the information. If writing is not your forte, get help.

To view writing strategies for successful applications, see our Sample Applications and More . There are many ways to create a great application, so explore your options.

Within the character limit, include the important information to distinguish your project within the research area, your project's goals, and the research problem.

Giving your project a title at the outset can help you stay focused and avoid a meandering Research Plan. So you may want to launch your writing by creating a well-defined title.

NIH gives you a 200 character limit, but don’t feel obliged to use all of that allotment. Instead, we advise you to keep the title as succinct as possible while including the important information to distinguish your project within the research area. Make your title reflect your project's goals, the problem your project addresses, and possibly your approach to studying it. Make your title specific: saying you are studying lymphocyte trafficking is not informative enough.

For examples of strong titles, see our Sample Applications and More .

After you write a preliminary title, check that

• My title is specific, indicating at least the research area and the goals of my project.
• It is 200 characters or less.
• I use as simple language as possible.
• I state the research problem and, possibly, my approach to studying it.
• I use a different title for each of my applications. (Note: there are exceptions, for example, for a renewal—see Apply for Renewal  for details.)
• My title has appropriate keywords.

Later you may want to change your initial title. That's fine—at this point, it's just an aid to keep your plans focused.

Since all your reviewers read your Specific Aims, you want to excite them about your project.

If testing your hypothesis is the destination for your research, your Research Plan is the map that takes you there.

You'll start by writing the smaller part, the Specific Aims. Think of the one-page Specific Aims as a capsule of your Research Plan. Since all your reviewers read your Specific Aims, you want to excite them about your project.

For more on crafting your Specific Aims, see Draft Specific Aims .

Write a Narrative

Use at least half the page to provide the rationale and significance of your planned research. A good way to start is with a sentence that states your project's goals.

For the rest of the narrative, you will describe the significance of your research, and give your rationale for choosing the project. In some cases, you may want to explain why you did not take an alternative route.

Then, briefly describe your aims, and show how they build on your preliminary studies and your previous research. State your hypothesis.

If it is likely your application will be reviewed by a study section with broad expertise, summarize the status of research in your field and explain how your project fits in.

In the narrative part of the Specific Aims of many outstanding applications, people also used their aims to

• State the technologies they plan to use.
• Note their expertise to do a specific task or that of collaborators.
• Describe past accomplishments related to the project.
• Describe preliminary studies and new and highly relevant findings in the field.
• Explain their area's biology.
• Show how the aims relate to one another.
• Describe expected outcomes for each aim.
• Explain how they plan to interpret data from the aim’s efforts.
• Describe how to address potential pitfalls with contingency plans.

Depending on your situation, decide which items are important for you. For example, a new investigator would likely want to highlight preliminary data and qualifications to do the work.

Many people use bold or italics to emphasize items they want to bring to the reviewers' attention, such as the hypothesis or rationale.

Detail Your Aims

After the narrative, enter your aims as bold bullets, or stand-alone or run-on headers.

• State your plans using strong verbs like identify, define, quantify, establish, determine.
• Describe each aim in one to three sentences.
• Consider adding bullets under each aim to refine your objectives.

How focused should your aims be? Look at the example below.

Spot the Sample

Read the Specific Aims of the Application from Drs. Li and Samulski , "Enhance AAV Liver Transduction with Capsid Immune Evasion."

• Aim 1. Study the effect of adeno-associated virus (AAV) empty particles on AAV capsid antigen cross-presentation in vivo .
• Aim 2. Investigate AAV capsid antigen presentation following administration of AAV mutants and/or proteasome inhibitors for enhanced liver transduction in vivo .
• Aim 3. Isolate AAV chimeric capsids with human hepatocyte tropism and the capacity for cytotoxic T lymphocytes (CTL) evasion.

After finishing the draft Specific Aims, check that

• I keep to the one-page limit.
• Each of my two or three aims is a narrowly focused, concrete objective I can achieve during the grant.
• They give a clear picture of how my project can generate knowledge that may improve human health.
• They show my project's importance to science, how it addresses a critical research opportunity that can move my field forward.
• My text states how my work is innovative.
• I describe the biology to the extent needed for my reviewers.
• I give a rationale for choosing the topic and approach.
• I tie the project to my preliminary data and other new findings in the field.
• I explicitly state my hypothesis and why testing it is important.
• My aims can test my hypothesis and are logical.
• I can design and lead the execution of two or three sets of experiments that will strive to accomplish each aim.
• As much as possible, I use language that an educated person without expertise can understand.
• My text has bullets, bolding, or headers so reviewers can easily spot my aims (and other key items).

For each element listed above, analyze your text and revise it until your Specific Aims hit all the key points you'd like to make.

After the list of aims, some people add a closing paragraph, emphasizing the significance of the work, their collaborators, or whatever else they want to focus reviewers' attention on.

Your Research Strategy is the bigger part of your application's Research Plan (the other part is the Specific Aims—discussed above.)

The Research Strategy is the nuts and bolts of your application, describing the rationale for your research and the experiments you will do to accomplish each aim. It is structured as follows:

• Significance
• You can either include this information as a subsection of Approach or integrate it into any or all of the three main sections.
• If you do the latter, be sure to mark the information clearly, for example, with a bold subhead.
• Possible other sections, for example, human subjects, vertebrate animals, select agents, and others (these do not count toward the page limit).

Though how you organize your application is largely up to you, NIH does want you to follow these guidelines:

• Add bold headers or an outlining or numbering system—or both—that you use consistently throughout.
• Start each of the Research Strategy's sections with a header: Significance, Innovation, and Approach.

For an R01, the Research Strategy is limited to 12 pages for the three main sections and the preliminary studies only. Other items are not included in the page limit.

Find instructions for R01s in the SF 424 Application Guide—go to NIH's SF 424 (R&R) Application and Electronic Submission Information for the generic SF 424 Application Guide or find it in your notice of funding opportunity (NOFO).

For most applications, you need to address Rigor and Reproducibility by describing the experimental design and methods you propose and how they will achieve robust and unbiased results. The requirement applies to research grant, career development, fellowship, and training applications.

If you're responding to an institute-specific program announcement (PA) (not a parent program announcement) or a request for applications (RFA), check the NIH Guide notice, which has additional information you need. Should it differ from the NOFO, go with the NIH Guide .

Also note that your application must meet the initiative's objectives and special requirements. NIAID program staff will check your application, and if it is not responsive to the announcement, your application will be returned to you without a review.

When writing your Research Strategy, your goal is to present a well-organized, visually appealing, and readable description of your proposed project. That means your writing should be streamlined and organized so your reviewers can readily grasp the information. If writing is not your forte, get help.

There are many ways to create an outstanding Research Plan, so explore your options.

What Success Looks Like

Your application's Research Plan is the map that shows your reviewers how you plan to test your hypothesis.

It not only lays out your experiments and expected outcomes, but must also convince your reviewers of your likely success by allaying any doubts that may cross their minds that you will be able to conduct the research.

Notice in the sample applications how the writing keeps reviewers' eyes on the ball by bringing them back to the main points the PIs want to make. Write yourself an insurance policy against human fallibility: if it's a key point, repeat it, then repeat it again.

The Big Three

So as you write, put the big picture squarely in your sights. When reviewers read your application, they'll look for the answers to three basic questions:

• Can your research move your field forward?
• Is the field important—will progress make a difference to human health?
• Can you and your team carry out the work?

Add Emphasis

Savvy PIs create opportunities to drive their main points home. They don't stop at the Significance section to emphasize their project's importance, and they look beyond their biosketches to highlight their team's expertise.

Don't take a chance your reviewer will gloss over that one critical sentence buried somewhere in your Research Strategy or elsewhere. Write yourself an insurance policy against human fallibility: if it's a key point, repeat it, then repeat it again.

Add more emphasis by putting the text in bold, or bold italics (in the modern age, we skip underlining—it's for typewriters).

Here are more strategies from our successful PIs:

• While describing a method in the Approach section, they state their or collaborators' experience with it.
• They point out that they have access to a necessary piece of equipment.
• When explaining their field and the status of current research, they weave in their own work and their preliminary data.
• They delve into the biology of the area to make sure reviewers will grasp the importance of their research and understand their field and how their work fits into it.

You can see many of these principles at work in the Approach section of the Application from Dr. William Faubion , "Inflammatory cascades disrupt Treg function through epigenetic mechanisms."

• Reviewers felt that the experiments described for Aim 1 will yield clear results.
• The plans to translate those findings to gene targets of relevance are well outlined and focused.
• He ties his proposed experiments to the larger picture, including past research and strong preliminary data for the current application. 

Anticipate Reviewer Questions

Our applicants not only wrote with their reviewers in mind they seemed to anticipate their questions. You may think: how can I anticipate all the questions people may have? Of course you can't, but there are some basic items (in addition to the "big three" listed above) that will surely be on your reviewers' minds:

• Will the investigators be able to get the work done within the project period, or is the proposed work over ambitious?
• Did the PI describe potential pitfalls and possible alternatives?
• Will the experiments generate meaningful data?
• Could the resulting data prove the hypothesis?
• Are others already doing the work, or has it been already completed?

Address these questions; then spend time thinking about more potential issues specific to you and your research—and address those too.

For applications, a picture can truly be worth a thousand words. Graphics can illustrate complex information in a small space and add visual interest to your application.

Look at our sample applications to see how the investigators included schematics, tables, illustrations, graphs, and other types of graphics to enhance their applications.

Consider adding a timetable or flowchart to illustrate your experimental plan, including decision trees with alternative experimental pathways to help your reviewers understand your plans.

Plan Ahead for Video

If you plan to send one or more videos, you'll need to meet certain standards and include key information in your Research Strategy now.

To present some concepts or demonstrations, video may enhance your application beyond what graphics alone can achieve. However, you can't count on all reviewers being able to see or hear video, so you'll want to be strategic in how you incorporate it into your application.

Be reviewer-friendly. Help your cause by taking the following steps:

• Caption any narration in the video.
• Choose evocative still images from your video to accompany your summary.
• Write your summary of the video carefully so the text would make sense even without the video.

In addition to those considerations, create your videos to fit NIH’s technical requirements. Learn more in the SF 424 Form Instructions .

Next, as you write your Research Strategy, include key images from the video and a brief description.

Then, state in your cover letter that you plan to send video later. (Don't attach your files to the application.)

After you apply and get assignment information from the Commons, ask your assigned scientific review officer (SRO) how your business official should send the files. Your video files are due at least one month before the peer review meeting.

Know Your Audience's Perspective

The primary audience for your application is your peer review group. Learn how to write for the reviewers who are experts in your field and those who are experts in other fields by reading Know Your Audience .

Be Organized: A B C or 1 2 3?

In the top-notch applications we reviewed, organization ruled but followed few rules. While you want to be organized, how you go about it is up to you.

Nevertheless, here are some principles to follow:

• Start each of the Research Strategy's sections with a header: Significance, Innovation, and Approach—this you must do.

The Research Strategy's page limit—12 for R01s—is for the three main parts: Significance, Innovation, and Approach and your preliminary studies (or a progress report if you're renewing your grant). Other sections, for example, research animals or select agents, do not have a page limit.

Although you will emphasize your project's significance throughout the application, the Significance section should give the most details. Don't skimp—the farther removed your reviewers are from your field, the more information you'll need to provide on basic biology, importance of the area, research opportunities, and new findings.

When you describe your project's significance, put it in the context of 1) the state of your field, 2) your long-term research plans, and 3) your preliminary data.

In our Sample Applications , you can see that both investigators and reviewers made a case for the importance of the research to improving human health as well as to the scientific field.

Look at the Significance section of the Application from Dr. Mengxi Jiang , "Intersection of polyomavirus infection and host cellular responses," to see how these elements combine to make a strong case for significance.

• Dr. Jiang starts with a summary of the field of polyomavirus research, identifying critical knowledge gaps in the field.
• The application ties the lab's previous discoveries and new research plans to filling those gaps, establishing the significance with context.
• Note the use of formatting, whitespace, and sectioning to highlight key points and make it easier for reviewers to read the text.

After conveying the significance of the research in several parts of the application, check that

• In the Significance section, I describe the importance of my hypothesis to the field (especially if my reviewers are not in it) and human disease.
• I also point out the project's significance throughout the application.
• The application shows that I am aware of opportunities, gaps, roadblocks, and research underway in my field.
• I state how my research will advance my field, highlighting knowledge gaps and showing how my project fills one or more of them.
• Based on my scan of the review committee roster, I determine whether I cannot assume my reviewers will know my field and provide some information on basic biology, the importance of the area, knowledge gaps, and new findings.

If you are either a new PI or entering a new area: be cautious about seeming too innovative. Not only is innovation just one of five review criteria, but there might be a paradigm shift in your area of science. A reviewer may take a challenge to the status quo as a challenge to his or her world view.

When you look at our sample applications, you see that both the new and experienced investigators are not generally shifting paradigms. They are using new approaches or models, working in new areas, or testing innovative ideas.

After finishing the draft innovation section, check that

• I show how my proposed research is new and unique, e.g., explores new scientific avenues, has a novel hypothesis, will create new knowledge.
• Most likely, I explain how my project's research can refine, improve, or propose a new application of an existing concept or method.
• Make a very strong case for challenging the existing paradigm.
• Have data to support the innovative approach.
• Have strong evidence that I can do the work.

In your Approach, you spell out a few sets of experiments to address each aim. As we noted above, it's a good idea to restate the key points you've made about your project's significance, its place in your field, and your long-term goals.

You're probably wondering how much detail to include.

If you look at our sample applications as a guide, you can see very different approaches. Though people generally used less detail than you'd see in a scientific paper, they do include some experimental detail.

Expect your assigned reviewers to scrutinize your approach: they will want to know what you plan to do and how you plan to do it.

NIH data show that of the peer review criteria, approach has the highest correlation with the overall impact score.

Look at the Application from Dr. Mengxi Jiang , "Intersection of polyomavirus infection and host cellular responses," to see how a new investigator handled the Approach section.

For an example of an experienced investigator's well-received Approach section, see the Application from Dr. William Faubion , "Inflammatory cascades disrupt Treg function through epigenetic mechanisms."

Especially if you are a new investigator, you need enough detail to convince reviewers that you understand what you are undertaking and can handle the method.

• Cite a publication that shows you can handle the method where you can, but give more details if you and your team don't have a proven record using the method—and state explicitly why you think you will succeed.
• If space is short, you could also focus on experiments that highlight your expertise or are especially interesting. For experiments that are pedestrian or contracted out, just list the method.

Be sure to lay out a plan for alternative experiments and approaches in case you get negative or surprising results. Show reviewers you have a plan for spending the four or five years you will be funded no matter where the experiments lead.

See the Application from Drs. Li and Samulski , "Enhance AAV Liver Transduction with Capsid Immune Evasion," for a strong Approach section covering potential. As an example, see section C.1.3.'s alternative approaches.

Here are some pointers for organizing your Approach:

• Enter a bold header for each Specific Aim.
• Under each aim, describe the first set of experiments.
• If you get result X, you will follow pathway X; if you get result Y, you will follow pathway Y.
• Consider illustrating this with a flowchart.

Trim the fat—omit all information not needed to make your case. If you try to wow reviewers with your knowledge, they'll find flaws and penalize you heavily. Don't give them ammunition by including anything you don't need.

As you design your experiments, keep a running tab of the following essential data on a separate piece of paper:

• Who. A list of people who will help you for your Key Personnel section later.
• What. A list of equipment and supplies for the experiments you plan.
• Time. Notes on how long each step takes. Timing directly affects your budget as well as how many Specific Aims you can realistically achieve.

Jotting this information down will help you Create a Budget and complete other sections later.

After finishing a draft Approach section, check that

• I include enough background and preliminary data to give reviewers the context and significance of my plans.
• They can test the hypothesis (or hypotheses).
• I show alternative experiments and approaches in case I get negative or surprising results.
• My experiments can yield meaningful data to test my hypothesis (or hypotheses).
• As a new investigator, I include enough detail to convince reviewers I understand and can handle a method. I reviewed the sample applications to see how much detail to use.
• If I or my team has experience with a method, I cite it; otherwise I include enough details to convince reviewers we can handle it.
• I describe the results I anticipate and their implications.
• I omit all information not needed to state my case.
• I keep track of and explain who will do what, what they will do, when and where they will do it, how long it will take, and how much money it will cost.
• My timeline shows when I expect to complete my aims.

If you are applying for a new application, include preliminary studies; for a renewal or a revision (a competing supplement to an existing grant), prepare a progress report instead.

Describing Preliminary Studies

Your preliminary studies show that you can handle the methods and interpret results. Here's where you build reviewer confidence that you are headed in the right direction by pursuing research that builds on your accomplishments.

Reviewers use your preliminary studies together with the biosketches to assess the investigator review criterion, which reflects the competence of the research team.

Give alternative interpretations to your data to show reviewers you've thought through problems in-depth and are prepared to meet future challenges. If you don't do this, the reviewers will!

Though you may include other people's publications, focus on your preliminary data or unpublished data from your lab and the labs of your team members as much as you can.

As we noted above, you can put your preliminary data anywhere in the Research Strategy that you feel is appropriate, but just make sure your reviewers will be able to distinguish it. Alternatively, you can create a separate section with its own header.

Including a Progress Report

If you are applying for a renewal or a revision (a competing supplement to an existing grant), prepare a progress report instead of preliminary studies.

Create a header so your program officer can easily find it and include the following information:

• Project period beginning and end dates.
• Summary of the importance of your findings in relation to your Specific Aims.
• Account of published and unpublished results, highlighting your progress toward achieving your Specific Aims.

Note: if you submit a renewal application before the due date of your progress report, you do not need to submit a separate progress report for your grant. However, you will need to submit it, if your renewal is not funded.

After finishing the draft, check that

• I interpret my preliminary results critically.
• There is enough information to show I know what I'm talking about.
• If my project is complex, I give more preliminary studies.
• I show how my previous experience prepared me for the new project.
• It's clear which data are mine and which are not.

References show your breadth of knowledge of the field. If you leave out an important work, reviewers may assume you're not aware of it.

Throughout your application, you will reference all relevant publications for the concepts underlying your research and your methods.

Read more about your Bibliography and References Cited at Add a Bibliography and Appendix .

• Throughout my application I cite the literature thoroughly but not excessively, adding citations for all references important to my work.
• I cite all papers important to my field, including those from potential reviewers.
• I include fewer than 100 citations (if possible).
• My Bibliography and References Cited form lists all my references.
• I refer to unpublished work, including information I learned through personal contacts.
• If I do not describe a method, I add a reference to the literature.

Look over what you've written with a critical eye of a reviewer to identify potential questions or weak spots.

Enlist others to do that too—they can look at your application with a fresh eye. Include people who aren't familiar with your research to make sure you can get your point across to someone outside your field.

As you finalize the details of your Research Strategy, you will also need to return to your Specific Aims to see if you must revise. See Draft Specific Aims .

After you finish your Research Plan, you are ready to write your Abstract (called Project Summary/Abstract) and Project Narrative, which are attachments to the Other Project Information form.

These sections may be small, but they're important.

• All your peer reviewers read your Abstract and narrative.
• Staff and automated systems in NIH's Center for Scientific Review use them to decide where to assign your application, even if you requested an institute and study section.
• They show the importance and health relevance of your research to members of the public and Congress who are interested in what NIH is funding with taxpayer dollars.

Be sure to omit confidential or proprietary information in these sections! When your application is funded, NIH enters your title and Abstract in the public RePORTER database.

Think brief and simple: to the extent that you can, write these sections in lay language, and include appropriate keywords, e.g., immunotherapy, genetic risk factors.

As NIH referral officers use these parts to direct your application to an institute for possible funding, your description can influence the choice they make.

Write a succinct summary of your project that both a scientist and a lay person can understand (to the extent that you can).

• Use your Specific Aims as a template—shorten it and simplify the language.
• In the first sentence, state the significance of your research to your field and relevance to NIAID's mission: to better understand, treat, and prevent infectious, immunologic, and allergic diseases.
• Next state your hypothesis and the innovative potential of your research.
• Then list and briefly describe your Specific Aims and long-term objectives.

In your Project Narrative, you have only a few sentences to drive home your project's potential to improve public health.

Check out these effective Abstracts and Narratives from our R01  Sample Applications :

• Application from Dr. Mengxi Jiang , "Intersection of polyomavirus infection and host cellular responses"
• Application from Dr. William Faubion , "Inflammatory cascades disrupt Treg function through epigenetic mechanisms"
• My Project Summary/Abstract and Project Narrative (and title) are accessible to a broad audience.
• They describe the significance of my research to my field and state my hypothesis, my aims, and the innovative potential of my research.
• My narrative describes my project's potential to improve public health.
• I do not include any confidential or proprietary information.
• I do not use graphs or images.
• My Abstract has keywords that are appropriate and distinct enough to avoid confusion with other terms.
• My title is specific and informative.

Previous Step

Have questions.

A program officer in your area of science can give you application advice, NIAID's perspective on your research, and confirmation that your proposed research fits within NIAID’s mission.

Find contacts and instructions at When to Contact an NIAID Program Officer .

Biology Research: Getting Started: Research Design/Methods

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Books on Research

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Experimental Design

Useful Resources

• Biological Procedures Online Biological Procedures Online, from BioMed Central, publishes articles that improve access to techniques and methods in the medical and biological sciences.
• Introduction to Designing Experiments A 7-part series from Films on Demand that includes how to design research, hypotheses, sampling, ethics and bias, and more.
• Exploring Qualitative Methods How to conduct research using qualitative data from Films on Demand.
• Organizing Quantitative Data Video from Films on Demand on using quantitative data.
• Statistics for Biologists This resource from Nature magazine offers guidance in using statistics in biology research

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Undergraduate Research

Participating in research as an undergraduate can be a very rewarding experience. Approximately 90% of Biology majors pursue an independent research project at some point during their undergraduate careers; some also pursue honors, and some do not.

Jump to:  How to get started In-department research Out-of-department research Questions about enrolling

How to Get Started

Biology majors in particular have a plethora of research opportunities in the Biology Department, departments in the Medical School, and labs at Hopkins Marine Station. To get started in searching for a potential lab, these are some great resources to consider:  

• Biology Department Faculty : Browse each faculty member's areas of research
• Research Areas : Search for a faculty member based on a particular area of interest within the field of Biology
• Community Academic Profiles : This site allows you to search for faculty labs in the Stanford School of Medicine. You can search by name, department, or even keyword. This is a useful tool if you know generally what area of research you would like to pursue, but are unsure of a specific lab that does what interests you.

Once you have narrowed down 3-5 of your top choices, use the following steps as a general guide:

Spend time thoroughly looking over the lab's website. This will give a lot of information including how large the lab is, what types of projects are underway, and how many and what kinds of publications are getting done.

Read through a few publications to familiarize yourself with the research. This will give you something to talk about when you set up a meeting with the faculty member, and it also shows a genuine interest in their work.

Email the faculty member asking for an appointment. Be sure to mention that you have looked through their website and publications. This shows that you have made an effort and have an interest in them specifically. Be prepared to discuss your specific research interests.

Send a generic email simply asking if there are spaces in their lab. This is not compelling, and you may not even get a response.

Assume that the faculty member knows who you are. Briefly introduce yourself as a Biology major interested in pursuing ____.

Remember: politeness and persistence are important!

In-Department Research (BIO 199)

Once you have found and been accepted into a lab, you are strongly encouraged to enroll in academic credit for your work in the lab. The general formula for determining units is: 1 unit=3 hours of work per week.

Working in a Lab in Biology

Students doing research in Biology Department labs can study anything from cell biology, genetics, and plants to ecology, conservation, and marine biology. To get academic credit for Biology Department research (which can also count toward Biology major electives and Biology Honors requirements), students should enroll in their faculty member's section of BIO 199.

Be sure to discuss the number of units and grading options ahead of time with your faculty research advisor. No petition is required to enroll in BIO 199, and students in any major are welcome to enroll provided they have permission from the faculty member.

Out-of-Department Research (BIO 199X)

Autumn 2024 – October 2, 2024, 3:00 pm Winter 2025 – January 15, 2025, 3:00 pm Spring 2025 – April 9, 2025, 3:00 pm

Working in a Lab Outside of Biology

Many students find research opportunities in labs outside the Biology Department.  BIO 199X is available for declared Biology majors only.  If you are not a Biology major, consider enrolling under your PI's home department subject code, e.g. MED 199. Once you declare the major, you will submit a BIO 199X petition and start enrolling under that subject code.

You must submit your BIO 199X petition within one quarter of declaring the Biology major in order to receive credit toward your major electives . 

For Honors, only your BIO 199/X units count from your junior and senior years.

Students only need to petition ONCE to work with the same sponsor. If you switch labs, you will be required to submit a new petition.

Appropriate Research Projects

The research field is expected to encompass biological concepts and processes. Projects should be empirical or theoretical biological research, consisting of independent and original scientific work by the student. Applied clinical, environmental, or technological studies may be appropriate in cases where there is a major analytical, experimental or observational component to the study, involving independent conceptual, field or laboratory work by the student. Simply collecting data or samples from human subjects or interviewees, collating data, doing repetitive technical work, or doing statistical analysis is not sufficient for Bio 199X credit. Students should discuss the nature of their projects with their Departmental advisors prior to petitioning for approval, if there is any doubt about appropriateness.

Research Sponsors

Sponsors should be Academic Council members (assistant, associate, or full professors) if possible. If you are not sure if your research sponsor is an Academic Council member, search on Stanford Who in the "Search in Stanford view." If your sponsor is not an Academic Council member you will need to find a faculty member in the Department of Biology to serve as a co-sponsor of your research. This can be your faculty advisor if appropriate.

Petition Procedure

To petition for BIO 199X credit , students must submit the following items to the Biology Form Submission website or in Gilbert 118:

Fill out the  Petition and Research Sponsorship Form  (Fillable)

Your research proposal should be at least 2-3 pages in length (double spaced, not including references and figures) and should be organized as described below using the following headings. Also please include your Sponsor's name and department at the top.

Title of Research Project

Objective of research . Briefly and clearly state the question that your research is designed to address. Explain the specific aims of the research.

Background and Significance . Using appropriate background information which is appropriately referenced, indicate the significance of your research.

Experimental design . Describe the project design you will use to carry out your research including methods and materials. Indicate how these techniques will allow you to address your research question. Note the following: 1) research involving vertebrate animals requires that your sponsor have an approved Animal Use Protocol on file with the University Panel on Laboratory Animal Care; 2) work with radioactive substances requires certification in the University’s radiation safety course; 3) work with pathogenic organisms requires special training and precautions 4) work with human material requires that you complete the Human Subjects Training. If any of these apply, describe them in your proposal.

Possible results . Describe the expected outcome of your research, indicating how the data collected will be used to draw conclusions regarding the research question. Throughout your proposal, be specific about your own work: do not simply state the goals of the lab in which you are working. Stress the biological concepts you are using and your understanding of the methodology. The proposal should clearly show some level of independence in your research, the feasibility of the project, and an understanding of the basic biology involved. If this is your first Quarter of Bio 199X and you do not yet have your own project, but are helping someone else in the lab on their project while learning concepts and methods, then describe the project that you are working on instead.

Print or email the  sponsor information sheet  and give it to your sponsor for their reference.

Submit your Petition Form and Research Description to both your PI and major advisor well ahead of the submission deadline! Both readers will need time to review your proposal and provide feedback for revisions.

Questions about enrolling?

If you're unsure if you should enroll in BIO 199, BIO 199X, or something else (e.g. MED 199), use this decision tree to make your decision. Still unsure?  ayalamac [at] stanford.edu (subject: BIO%20199X%20Enrollment) (Contact the student services office) .  

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Writing the Research Plan for Your Academic Job Application

By Jason G. Gillmore, Ph.D., Associate Professor, Department of Chemistry, Hope College, Holland, MI

A research plan is more than a to-do list for this week in lab, or a manila folder full of ideas for maybe someday—at least if you are thinking of a tenure-track academic career in chemistry at virtually any bachelor’s or higher degree–granting institution in the country. A perusal of the academic job ads in C&EN every August–October will quickly reveal that most schools expect a cover letter (whether they say so or not), a CV, a teaching statement, and a research plan, along with reference letters and transcripts. So what is this document supposed to be, and why worry about it now when those job ads are still months away?

What Is a Research Plan?

A research plan is a thoughtful, compelling, well-written document that outlines your exciting, unique research ideas that you and your students will pursue over the next half decade or so to advance knowledge in your discipline and earn you grants, papers, speaking invitations, tenure, promotion, and a national reputation. It must be a document that people at the department you hope to join will (a) read, and (b) be suitably excited about to invite you for an interview.

That much I knew when I was asked to write this article. More specifics I only really knew for my own institution, Hope College (a research intensive undergraduate liberal arts college with no graduate program), and even there you might get a dozen nuanced opinions among my dozen colleagues. So I polled a broad cross-section of my network, spanning chemical subdisciplines at institutions ranging from small, teaching-centered liberal arts colleges to our nation’s elite research programs, such as Scripps and MIT. The responses certainly varied, but they did center on a few main themes, or illustrate a trend across institution types. In this article I’ll share those commonalities, while also encouraging you to be unafraid to contact a search committee chair with a few specific questions, especially for the institutions you are particularly excited about and feel might be the best fit for you.

How Many Projects Should You Have?

While more senior advisors and members of search committees may have gotten their jobs with a single research project, conventional wisdom these days is that you need two to three distinct but related projects. How closely related to one another they should be is a matter of debate, but almost everyone I asked felt that there should be some unifying technique, problem or theme to them. However, the projects should be sufficiently disparate that a failure of one key idea, strategy, or technique will not hamstring your other projects.

For this reason, many applicants wisely choose to identify:

• One project that is a safe bet—doable, fundable, publishable, good but not earthshaking science.
• A second project that is pie-in-the-sky with high risks and rewards.
• A third project that fits somewhere in the middle.

Having more than three projects is probably unrealistic. But even the safest project must be worth doing, and even the riskiest must appear to have a reasonable chance of working.

How Closely Connected Should Your Research Be with Your Past?

Your proposed research must do more than extend what you have already done. In most subdisciplines, you must be sufficiently removed from your postdoctoral or graduate work that you will not be lambasted for clinging to an advisor’s apron strings. After all, if it is such a good idea in their immediate area of interest, why aren’t they pursuing it?!?

But you also must be able to make the case for why your training makes this a good problem for you to study—how you bring a unique skill set as well as unique ideas to this research. The five years you will have to do, fund, and publish the research before crafting your tenure package will go by too fast for you to break into something entirely outside your realm of expertise.

Biochemistry is a partial exception to this advice—in this subdiscipline it is quite common to bring a project with you from a postdoc (or more rarely your Ph.D.) to start your independent career. However, you should still articulate your original contribution to, and unique angle on the work. It is also wise to be sure your advisor tells that same story in his or her letter and articulates support of your pursuing this research in your career as a genuinely independent scientist (and not merely someone who could be perceived as his or her latest "flunky" of a collaborator.)

Should You Discuss Potential Collaborators?

Regarding collaboration, tread lightly as a young scientist seeking or starting an independent career. Being someone with whom others can collaborate in the future is great. Relying on collaborators for the success of your projects is unwise. Be cautious about proposing to continue collaborations you already have (especially with past advisors) and about starting new ones where you might not be perceived as the lead PI. Also beware of presuming you can help advance the research of someone already in a department. Are they still there? Are they still doing that research? Do they actually want that help—or will they feel like you are criticizing or condescending to them, trying to scoop them, or seeking to ride their coattails? Some places will view collaboration very favorably, but the safest route is to cautiously float such ideas during interviews while presenting research plans that are exciting and achievable on your own.

How Do You Show Your Fit?

Some faculty advise tailoring every application packet document to every institution to which you apply, while others suggest tweaking only the cover letter. Certainly the cover letter is the document most suited to introducing yourself and making the case for how you are the perfect fit for the advertised position at that institution. So save your greatest degree of tailoring for your cover letter. It is nice if you can tweak a few sentences of other documents to highlight your fit to a specific school, so long as it is not contrived.

Now, if you are applying to widely different types of institutions, a few different sets of documents will certainly be necessary. The research plan that you target in the middle to get you a job at both Harvard University and Hope College will not get you an interview at either! There are different realities of resources, scope, scale, and timeline. Not that my colleagues and I at Hope cannot tackle research that is just as exciting as Harvard’s. However, we need to have enough of a niche or a unique angle both to endure the longer timeframe necessitated by smaller groups of undergraduate researchers and to ensure that we still stand out. Furthermore, we generally need to be able to do it with more limited resources. If you do not demonstrate that understanding, you will be dismissed out of hand. But at many large Ph.D. programs, any consideration of "niche" can be inferred as a lack of confidence or ambition.

Also, be aware that department Web pages (especially those several pages deep in the site, or maintained by individual faculty) can be woefully out-of-date. If something you are planning to say is contingent on something you read on their Web site, find a way to confirm it!

While the research plan is not the place to articulate start-up needs, you should consider instrumentation and other resources that will be necessary to get started, and where you will go for funding or resources down the road. This will come up in interviews, and hopefully you will eventually need these details to negotiate a start-up package.

Who Is Your Audience?

Your research plan should show the big picture clearly and excite a broad audience of chemists across your sub-discipline. At many educational institutions, everyone in the department will read the proposal critically, at least if you make the short list to interview. Even at departments that leave it all to a committee of the subdiscipline, subdisciplines can be broad and might even still have an outside member on the committee. And the committee needs to justify their actions to the department at large, as well as to deans, provosts, and others. So having at least the introduction and executive summaries of your projects comprehensible and compelling to those outside your discipline is highly advantageous.

Good science, written well, makes a good research plan. As you craft and refine your research plan, keep the following strategies, as well as your audience in mind:

• Begin the document with an abstract or executive summary that engages a broad audience and shows synergies among your projects. This should be one page or less, and you should probably write it last. This page is something you could manageably consider tailoring to each institution.
• Provide sufficient details and references to convince the experts you know your stuff and actually have a plan for what your group will be doing in the lab. Give details of first and key experiments, and backup plans or fallback positions for their riskiest aspects.
• Hook your readers with your own ideas fairly early in the document, then strike a balance between your own new ideas and the necessary well referenced background, precedents, and justification throughout. Propose a reasonable tentative timeline, if you can do so in no more than a paragraph or two, which shows how you envision spacing out the experiments within and among your projects. This may fit well into your executive summary
• Show how you will involve students (whether undergraduates, graduate students, an eventual postdoc or two, possibly even high schoolers if the school has that sort of outreach, depending on the institutions to which you are applying) and divide the projects among students.
• Highlight how your work will contribute to the education of these students. While this is especially important at schools with greater teaching missions, it can help set you apart even at research intensive institutions. After all, we all have to demonstrate “broader impacts” to our funding agencies!
• Include where you will pursue funding, as well as publication, if you can smoothly work it in. This is especially true if there is doubt about how you plan to target or "market" your research. Otherwise, it is appropriate to hold off until the interview to discuss this strategy.

So, How Long Should Your Research Plan Be?

Learn more on the Blog

Here is where the answers diverged the most and without a unifying trend across institutions. Bottom line, you need space to make your case, but even more, you need people to read what you write.

A single page abstract or executive summary of all your projects together provides you an opportunity to make the case for unifying themes yet distinct projects. It may also provide space to articulate a timeline. Indeed, many readers will only read this single page in each application, at least until winnowing down to a more manageable list of potential candidates. At the most elite institutions, there may be literally hundreds of applicants, scores of them entirely well-suited to the job.

While three to five pages per proposal was a common response (single spaced, in 11-point Arial or 12-point Times with one inch margins), including references (which should be accurate, appropriate, and current!), some of my busiest colleagues have said they will not read more than about three pages total. Only a few actually indicated they would read up to 12-15 pages for three projects. In my opinion, ten pages total for your research plans should be a fairly firm upper limit unless you are specifically told otherwise by a search committee, and then only if you have two to three distinct proposals.

Why Start Now?

Hopefully, this question has answered itself already! Your research plan needs to be a well thought out document that is an integrated part of applications tailored to each institution to which you apply. It must represent mature ideas that you have had time to refine through multiple revisions and a great deal of critical review from everyone you can get to read them. Moreover, you may need a few different sets of these, especially if you will be applying to a broad range of institutions. So add “write research plans” to this week’s to do list (and every week’s for the next few months) and start writing up the ideas in that manila folder into some genuine research plans. See which ones survive the process and rise to the top and you should be well prepared when the job ads begin to appear in C&EN in August!

Jason G. Gillmore , Ph.D., is an Associate Professor of Chemistry at Hope College in Holland, MI. A native of New Jersey, he earned his B.S. (’96) and M.S. (’98) degrees in chemistry from Virginia Tech, and his Ph.D. (’03) in organic chemistry from the University of Rochester. After a short postdoctoral traineeship at Vanderbilt University, he joined the faculty at Hope in 2004. He has received the Dreyfus Start-up Award, Research Corporation Cottrell College Science Award, and NSF CAREER Award, and is currently on sabbatical as a Visiting Research Professor at Arizona State University. Professor Gillmore is the organizer of the Biennial Midwest Postdoc to PUI Professor (P3) Workshop co-sponsored by ACS, and a frequent panelist at the annual ACS Postdoc to Faculty (P2F) Workshops.

Other tips to help engage (or at least not turn off) your readers include:

• Avoid two-column formats.
• Avoid too-small fonts that hinder readability, especially as many will view the documents online rather than in print!
• Use good figures that are readable and broadly understandable!
• Use color as necessary but not gratuitously.

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How to prepare a Research Proposal

Health research, medical education and clinical practice form the three pillars of modern day medical practice. As one authority rightly put it: ‘Health research is not a luxury, but an essential need that no nation can afford to ignore’. Health research can and should be pursued by a broad range of people. Even if they do not conduct research themselves, they need to grasp the principles of the scientific method to understand the value and limitations of science and to be able to assess and evaluate results of research before applying them. This review paper aims to highlight the essential concepts to the students and beginning researchers and sensitize and motivate the readers to access the vast literature available on research methodologies.

Most students and beginning researchers do not fully understand what a research proposal means, nor do they understand its importance. 1 A research proposal is a detailed description of a proposed study designed to investigate a given problem. 2

A research proposal is intended to convince others that you have a worthwhile research project and that you have the competence and the work-plan to complete it. Broadly the research proposal must address the following questions regardless of your research area and the methodology you choose: What you plan to accomplish, why do you want to do it and how are you going to do it. 1 The aim of this article is to highlight the essential concepts and not to provide extensive details about this topic.

The elements of a research proposal are highlighted below:

1. Title: It should be concise and descriptive. It must be informative and catchy. An effective title not only prick’s the readers interest, but also predisposes him/her favorably towards the proposal. Often titles are stated in terms of a functional relationship, because such titles clearly indicate the independent and dependent variables. 1 The title may need to be revised after completion of writing of the protocol to reflect more closely the sense of the study. 3

2. Abstract: It is a brief summary of approximately 300 words. It should include the main research question, the rationale for the study, the hypothesis (if any) and the method. Descriptions of the method may include the design, procedures, the sample and any instruments that will be used. 1 It should stand on its own, and not refer the reader to points in the project description. 3

3. Introduction: The introduction provides the readers with the background information. Its purpose is to establish a framework for the research, so that readers can understand how it relates to other research. 4 It should answer the question of why the research needs to be done and what will be its relevance. It puts the proposal in context. 3

The introduction typically begins with a statement of the research problem in precise and clear terms. 1

The importance of the statement of the research problem 5 : The statement of the problem is the essential basis for the construction of a research proposal (research objectives, hypotheses, methodology, work plan and budget etc). It is an integral part of selecting a research topic. It will guide and put into sharper focus the research design being considered for solving the problem. It allows the investigator to describe the problem systematically, to reflect on its importance, its priority in the country and region and to point out why the proposed research on the problem should be undertaken. It also facilitates peer review of the research proposal by the funding agencies.

Then it is necessary to provide the context and set the stage for the research question in such a way as to show its necessity and importance. 1 This step is necessary for the investigators to familiarize themselves with existing knowledge about the research problem and to find out whether or not others have investigated the same or similar problems. This step is accomplished by a thorough and critical review of the literature and by personal communication with experts. 5 It helps further understanding of the problem proposed for research and may lead to refining the statement of the problem, to identify the study variables and conceptualize their relationships, and in formulation and selection of a research hypothesis. 5 It ensures that you are not "re-inventing the wheel" and demonstrates your understanding of the research problem. It gives due credit to those who have laid the groundwork for your proposed research. 1 In a proposal, the literature review is generally brief and to the point. The literature selected should be pertinent and relevant. 6

Against this background, you then present the rationale of the proposed study and clearly indicate why it is worth doing.

4. Objectives: Research objectives are the goals to be achieved by conducting the research. 5 They may be stated as ‘general’ and ‘specific’.

The general objective of the research is what is to be accomplished by the research project, for example, to determine whether or not a new vaccine should be incorporated in a public health program.

The specific objectives relate to the specific research questions the investigator wants to answer through the proposed study and may be presented as primary and secondary objectives, for example, primary: To determine the degree of protection that is attributable to the new vaccine in a study population by comparing the vaccinated and unvaccinated groups. 5 Secondary: To study the cost-effectiveness of this programme.

Young investigators are advised to resist the temptation to put too many objectives or over-ambitious objectives that cannot be adequately achieved by the implementation of the protocol. 3

5. Variables: During the planning stage, it is necessary to identify the key variables of the study and their method of measurement and unit of measurement must be clearly indicated. Four types of variables are important in research 5 :

a. Independent variables: variables that are manipulated or treated in a study in order to see what effect differences in them will have on those variables proposed as being dependent on them. The different synonyms for the term ‘independent variable’ which are used in literature are: cause, input, predisposing factor, risk factor, determinant, antecedent, characteristic and attribute.

b. Dependent variables: variables in which changes are results of the level or amount of the independent variable or variables.

Synonyms: effect, outcome, consequence, result, condition, disease.

c. Confounding or intervening variables: variables that should be studied because they may influence or ‘mix’ the effect of the independent variables. For instance, in a study of the effect of measles (independent variable) on child mortality (dependent variable), the nutritional status of the child may play an intervening (confounding) role.

d. Background variables: variables that are so often of relevance in investigations of groups or populations that they should be considered for possible inclusion in the study. For example sex, age, ethnic origin, education, marital status, social status etc.

The objective of research is usually to determine the effect of changes in one or more independent variables on one or more dependent variables. For example, a study may ask "Will alcohol intake (independent variable) have an effect on development of gastric ulcer (dependent variable)?"

Certain variables may not be easy to identify. The characteristics that define these variables must be clearly identified for the purpose of the study.

6. Questions and/ or hypotheses: If you as a researcher know enough to make prediction concerning what you are studying, then the hypothesis may be formulated. A hypothesis can be defined as a tentative prediction or explanation of the relationship between two or more variables. In other words, the hypothesis translates the problem statement into a precise, unambiguous prediction of expected outcomes. Hypotheses are not meant to be haphazard guesses, but should reflect the depth of knowledge, imagination and experience of the investigator. 5 In the process of formulating the hypotheses, all variables relevant to the study must be identified. For example: "Health education involving active participation by mothers will produce more positive changes in child feeding than health education based on lectures". Here the independent variable is types of health education and the dependent variable is changes in child feeding.

A research question poses a relationship between two or more variables but phrases the relationship as a question; a hypothesis represents a declarative statement of the relations between two or more variables. 7

For exploratory or phenomenological research, you may not have any hypothesis (please do not confuse the hypothesis with the statistical null hypothesis). 1 Questions are relevant to normative or census type research (How many of them are there? Is there a relationship between them?). Deciding whether to use questions or hypotheses depends on factors such as the purpose of the study, the nature of the design and methodology, and the audience of the research (at times even the outlook and preference of the committee members, particularly the Chair). 6

7. Methodology: The method section is very important because it tells your research Committee how you plan to tackle your research problem. The guiding principle for writing the Methods section is that it should contain sufficient information for the reader to determine whether the methodology is sound. Some even argue that a good proposal should contain sufficient details for another qualified researcher to implement the study. 1 Indicate the methodological steps you will take to answer every question or to test every hypothesis illustrated in the Questions/hypotheses section. 6 It is vital that you consult a biostatistician during the planning stage of your study, 8 to resolve the methodological issues before submitting the proposal.

This section should include:

Research design: The selection of the research strategy is the core of research design and is probably the single most important decision the investigator has to make. The choice of the strategy, whether descriptive, analytical, experimental, operational or a combination of these depend on a number of considerations, 5 but this choice must be explained in relation to the study objectives. 3

Research subjects or participants: Depending on the type of your study, the following questions should be answered 3 , 5

• - What are the criteria for inclusion or selection?
• - What are the criteria for exclusion?
• - What is the sampling procedure you will use so as to ensure representativeness and reliability of the sample and to minimize sampling errors? The key reason for being concerned with sampling is the issue of validity-both internal and external of the study results. 9
• - Will there be use of controls in your study? Controls or comparison groups are used in scientific research in order to increase the validity of the conclusions. Control groups are necessary in all analytical epidemiological studies, in experimental studies of drug trials, in research on effects of intervention programmes and disease control measures and in many other investigations. Some descriptive studies (studies of existing data, surveys) may not require control groups.
• - What are the criteria for discontinuation?

Sample size: The proposal should provide information and justification (basis on which the sample size is calculated) about sample size in the methodology section. 3 A larger sample size than needed to test the research hypothesis increases the cost and duration of the study and will be unethical if it exposes human subjects to any potential unnecessary risk without additional benefit. A smaller sample size than needed can also be unethical as it exposes human subjects to risk with no benefit to scientific knowledge. Calculation of sample size has been made easy by computer software programmes, but the principles underlying the estimation should be well understood.

Interventions: If an intervention is introduced, a description must be given of the drugs or devices (proprietary names, manufacturer, chemical composition, dose, frequency of administration) if they are already commercially available. If they are in phases of experimentation or are already commercially available but used for other indications, information must be provided on available pre-clinical investigations in animals and/or results of studies already conducted in humans (in such cases, approval of the drug regulatory agency in the country is needed before the study). 3

Ethical issues 3 : Ethical considerations apply to all types of health research. Before the proposal is submitted to the Ethics Committee for approval, two important documents mentioned below (where appropriate) must be appended to the proposal. In additions, there is another vital issue of Conflict of Interest, wherein the researchers should furnish a statement regarding the same.

The Informed consent form (informed decision-making): A consent form, where appropriate, must be developed and attached to the proposal. It should be written in the prospective subjects’ mother tongue and in simple language which can be easily understood by the subject. The use of medical terminology should be avoided as far as possible. Special care is needed when subjects are illiterate. It should explain why the study is being done and why the subject has been asked to participate. It should describe, in sequence, what will happen in the course of the study, giving enough detail for the subject to gain a clear idea of what to expect. It should clarify whether or not the study procedures offer any benefits to the subject or to others, and explain the nature, likelihood and treatment of anticipated discomfort or adverse effects, including psychological and social risks, if any. Where relevant, a comparison with risks posed by standard drugs or treatment must be included. If the risks are unknown or a comparative risk cannot be given it should be so stated. It should indicate that the subject has the right to withdraw from the study at any time without, in any way, affecting his/her further medical care. It should assure the participant of confidentiality of the findings.

Ethics checklist: The proposal must describe the measures that will be undertaken to ensure that the proposed research is carried out in accordance with the World Medical Association Declaration of Helsinki on Ethical Principles for Medical research involving Human Subjects. 10 It must answer the following questions:

• • Is the research design adequate to provide answers to the research question? It is unethical to expose subjects to research that will have no value.
• • Is the method of selection of research subjects justified? The use of vulnerable subjects as research participants needs special justification. Vulnerable subjects include those in prison, minors and persons with mental disability. In international research it is important to mention that the population in which the study is conducted will benefit from any potential outcome of the research and the research is not being conducted solely for the benefit of some other population. Justification is needed for any inducement, financial or otherwise, for the participants to be enrolled in the study.
• • Are the interventions justified, in terms of risk/benefit ratio? Risks are not limited to physical harm. Psychological and social risks must also be considered.
• • For observations made, have measures been taken to ensure confidentiality?

Research setting 5 : The research setting includes all the pertinent facets of the study, such as the population to be studied (sampling frame), the place and time of study.

Study instruments 3 , 5 : Instruments are the tools by which the data are collected. For validated questionnaires/interview schedules, reference to published work should be given and the instrument appended to the proposal. For new a questionnaire which is being designed specifically for your study the details about preparing, precoding and pretesting of questionnaire should be furnished and the document appended to the proposal. Descriptions of other methods of observations like medical examination, laboratory tests and screening procedures is necessary- for established procedures, reference of published work cited but for new or modified procedure, an adequate description is necessary with justification for the same.

Collection of data: A short description of the protocol of data collection. For example, in a study on blood pressure measurement: time of participant arrival, rest for 5p. 10 minutes, which apparatus (standard calibrated) to be used, in which room to take measurement, measurement in sitting or lying down position, how many measurements, measurement in which arm first (whether this is going to be randomized), details of cuff and its placement, who will take the measurement. This minimizes the possibility of confusion, delays and errors.

Data analysis: The description should include the design of the analysis form, plans for processing and coding the data and the choice of the statistical method to be applied to each data. What will be the procedures for accounting for missing, unused or spurious data?

Monitoring, supervision and quality control: Detailed statement about the all logistical issues to satisfy the requirements of Good Clinical Practices (GCP), protocol procedures, responsibilities of each member of the research team, training of study investigators, steps taken to assure quality control (laboratory procedures, equipment calibration etc)

Gantt chart: A Gantt chart is an overview of tasks/proposed activities and a time frame for the same. You put weeks, days or months at one side, and the tasks at the other. You draw fat lines to indicate the period the task will be performed to give a timeline for your research study (take help of tutorial on youtube). 11

Significance of the study: Indicate how your research will refine, revise or extend existing knowledge in the area under investigation. How will it benefit the concerned stakeholders? What could be the larger implications of your research study?

Dissemination of the study results: How do you propose to share the findings of your study with professional peers, practitioners, participants and the funding agency?

Budget: A proposal budget with item wise/activity wise breakdown and justification for the same. Indicate how will the study be financed.

References: The proposal should end with relevant references on the subject. For web based search include the date of access for the cited website, for example: add the sentence "accessed on June 10, 2008".

Appendixes: Include the appropriate appendixes in the proposal. For example: Interview protocols, sample of informed consent forms, cover letters sent to appropriate stakeholders, official letters for permission to conduct research. Regarding original scales or questionnaires, if the instrument is copyrighted then permission in writing to reproduce the instrument from the copyright holder or proof of purchase of the instrument must be submitted.

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Biology Research Topics

Are you in need of captivating and achievable research topics within the field of biology? Your quest for the best biology topics ends right here as this article furnishes you with 100 distinctive and original concepts for biology research, laying the groundwork for your research endeavor.

Table of Contents

Our proficient researchers have thoughtfully curated these biology research themes, considering the substantial body of literature accessible and the prevailing gaps in research.

Should none of these topics elicit enthusiasm, our specialists are equally capable of proposing tailor-made research ideas in biology, finely tuned to cater to your requirements. 

Thus, without further delay, we present our compilation of biology research topics crafted to accommodate students and researchers.

Research Topics in Marine Biology

• Impact of climate change on coral reef ecosystems.
• Biodiversity and adaptation of deep-sea organisms.
• Effects of pollution on marine life and ecosystems.
• Role of marine protected areas in conserving biodiversity.
• Microplastics in marine environments: sources, impacts, and mitigation.

Biological Anthropology Research Topics

• Evolutionary implications of early human migration patterns.
• Genetic and environmental factors influencing human height variation.
• Cultural evolution and its impact on human societies.
• Paleoanthropological insights into human dietary adaptations.
• Genetic diversity and population history of indigenous communities.

Biological Psychology Research Topics 

• Neurobiological basis of addiction and its treatment.
• Impact of stress on brain structure and function.
• Genetic and environmental influences on mental health disorders.
• Neural mechanisms underlying emotions and emotional regulation.
• Role of the gut-brain axis in psychological well-being.

Cancer Biology Research Topics 

• Targeted therapies in precision cancer medicine.
• Tumor microenvironment and its influence on cancer progression.
• Epigenetic modifications in cancer development and therapy.
• Immune checkpoint inhibitors and their role in cancer immunotherapy.
• Early detection and diagnosis strategies for various types of cancer.

Also read: Cancer research topics

Cell Biology Research Topics

• Mechanisms of autophagy and its implications in health and disease.
• Intracellular transport and organelle dynamics in cell function.
• Role of cell signaling pathways in cellular response to external stimuli.
• Cell cycle regulation and its relevance to cancer development.
• Cellular mechanisms of apoptosis and programmed cell death.

Developmental Biology Research Topics 

• Genetic and molecular basis of limb development in vertebrates.
• Evolution of embryonic development and its impact on morphological diversity.
• Stem cell therapy and regenerative medicine approaches.
• Mechanisms of organogenesis and tissue regeneration in animals.
• Role of non-coding RNAs in developmental processes.

Also read: Education research topics

Human Biology Research Topics

• Genetic factors influencing susceptibility to infectious diseases.
• Human microbiome and its impact on health and disease.
• Genetic basis of rare and common human diseases.
• Genetic and environmental factors contributing to aging.
• Impact of lifestyle and diet on human health and longevity.

Molecular Biology Research Topics 

• CRISPR-Cas gene editing technology and its applications.
• Non-coding RNAs as regulators of gene expression.
• Role of epigenetics in gene regulation and disease.
• Mechanisms of DNA repair and genome stability.
• Molecular basis of cellular metabolism and energy production.

Research Topics in Biology for Undergraduates

• 41. Investigating the effects of pollutants on local plant species.
• Microbial diversity and ecosystem functioning in a specific habitat.
• Understanding the genetics of antibiotic resistance in bacteria.
• Impact of urbanization on bird populations and biodiversity.
• Investigating the role of pheromones in insect communication.

Also read: Psychology Research Topics

Synthetic Biology Research Topics 

• Design and construction of synthetic biological circuits.
• Synthetic biology applications in biofuel production.
• Ethical considerations in synthetic biology research and applications.
• Synthetic biology approaches to engineering novel enzymes.
• Creating synthetic organisms with modified functions and capabilities.

Animal Biology Research Topics 

• Evolution of mating behaviors in animal species.
• Genetic basis of color variation in butterfly wings.
• Impact of habitat fragmentation on amphibian populations.
• Behavior and communication in social insect colonies.
• Adaptations of marine mammals to aquatic environments.

Also read: Nursing research topics

Best Biology Research Topics 

• Unraveling the mysteries of circadian rhythms in organisms.
• Investigating the ecological significance of cryptic coloration.
• Evolution of venomous animals and their prey.
• The role of endosymbiosis in the evolution of eukaryotic cells.
• Exploring the potential of extremophiles in biotechnology.

Biological Psychology Research Paper Topics

• Neurobiological mechanisms underlying memory formation.
• Impact of sleep disorders on cognitive function and mental health.
• Biological basis of personality traits and behavior.
• Neural correlates of emotions and emotional disorders.
• Role of neuroplasticity in brain recovery after injury.

Biological Science Research Topics: 

• Role of gut microbiota in immune system development.
• Molecular mechanisms of gene regulation during development.
• Impact of climate change on insect population dynamics.
• Genetic basis of neurodegenerative diseases like Alzheimer’s.
• Evolutionary relationships among vertebrate species based on DNA analysis.

Biology Education Research Topics 

• Effectiveness of inquiry-based learning in biology classrooms.
• Assessing the impact of virtual labs on student understanding of biology concepts.
• Gender disparities in science education and strategies for closing the gap.
• Role of outdoor education in enhancing students’ ecological awareness.
• Integrating technology in biology education: challenges and opportunities.

Biology-Related Research Topics

• The intersection of ecology and economics in conservation planning.
• Molecular basis of antibiotic resistance in pathogenic bacteria.
• Implications of genetic modification of crops for food security.
• Evolutionary perspectives on cooperation and altruism in animal behavior.
• Environmental impacts of genetically modified organisms (GMOs).

Biology Research Proposal Topics

• Investigating the role of microRNAs in cancer progression.
• Exploring the effects of pollution on aquatic biodiversity.
• Developing a gene therapy approach for a genetic disorder.
• Assessing the potential of natural compounds as anti-inflammatory agents.
• Studying the molecular basis of cellular senescence and aging.

Biology Research Topic Ideas

• Role of pheromones in insect mate selection and behavior.
• Investigating the molecular basis of neurodevelopmental disorders.
• Impact of climate change on plant-pollinator interactions.
• Genetic diversity and conservation of endangered species.
• Evolutionary patterns in mimicry and camouflage in organisms.

Biology Research Topics for Undergraduates 

• Effects of different fertilizers on plant growth and soil health.
• Investigating the biodiversity of a local freshwater ecosystem.
• Evolutionary origins of a specific animal adaptation.
• Genetic diversity and disease susceptibility in human populations.
• Role of specific genes in regulating the immune response.

Cell and Molecular Biology Research Topics 

• Molecular mechanisms of DNA replication and repair.
• Role of microRNAs in post-transcriptional gene regulation.
• Investigating the cell cycle and its control mechanisms.
• Molecular basis of mitochondrial diseases and therapies.
• Cellular responses to oxidative stress and their implications in ageing.

These topics cover a broad range of subjects within biology, offering plenty of options for research projects. Remember that you can further refine these topics based on your specific interests and research goals.

Frequently Asked Questions 

What are some good research topics in biology?

A good research topic in biology will address a specific problem in any of the several areas of biology, such as marine biology, molecular biology, cellular biology, animal biology, or cancer biology.

A topic that enables you to investigate a problem in any area of biology will help you make a meaningful contribution. 

How to choose a research topic in biology?

Choosing a research topic in biology is simple. 

Follow the steps:

• Generate potential topics. 
• Consider your areas of knowledge and personal passions. 
• Conduct a thorough review of existing literature.
•  Evaluate the practicality and viability. 
• Narrow down and refine your research query. 
• Remain receptive to new ideas and suggestions.

Who Are We?

For several years, Research Prospect has been offering students around the globe complimentary research topic suggestions. We aim to assist students in choosing a research topic that is both suitable and feasible for their project, leading to the attainment of their desired grades. Explore how our services, including research proposal writing , dissertation outline creation, and comprehensive thesis writing , can contribute to your college’s success.

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Writing a Scientific Research Project Proposal

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The importance of a well-written research proposal cannot be underestimated. Your research really is only as good as your proposal. A poorly written, or poorly conceived research proposal will doom even an otherwise worthy project. On the other hand, a well-written, high-quality proposal will increase your chances for success.

In this article, we’ll outline the basics of writing an effective scientific research proposal, including the differences between research proposals, grants and cover letters. We’ll also touch on common mistakes made when submitting research proposals, as well as a simple example or template that you can follow.

What is a scientific research proposal?

The main purpose of a scientific research proposal is to convince your audience that your project is worthwhile, and that you have the expertise and wherewithal to complete it. The elements of an effective research proposal mirror those of the research process itself, which we’ll outline below. Essentially, the research proposal should include enough information for the reader to determine if your proposed study is worth pursuing.

It is not an uncommon misunderstanding to think that a research proposal and a cover letter are the same things. However, they are different. The main difference between a research proposal vs cover letter content is distinct. Whereas the research proposal summarizes the proposal for future research, the cover letter connects you to the research, and how you are the right person to complete the proposed research.

There is also sometimes confusion around a research proposal vs grant application. Whereas a research proposal is a statement of intent, related to answering a research question, a grant application is a specific request for funding to complete the research proposed. Of course, there are elements of overlap between the two documents; it’s the purpose of the document that defines one or the other.

Scientific Research Proposal Format

Although there is no one way to write a scientific research proposal, there are specific guidelines. A lot depends on which journal you’re submitting your research proposal to, so you may need to follow their scientific research proposal template.

In general, however, there are fairly universal sections to every scientific research proposal. These include:

• Title: Make sure the title of your proposal is descriptive and concise. Make it catch and informative at the same time, avoiding dry phrases like, “An investigation…” Your title should pique the interest of the reader.
• Abstract: This is a brief (300-500 words) summary that includes the research question, your rationale for the study, and any applicable hypothesis. You should also include a brief description of your methodology, including procedures, samples, instruments, etc.
• Introduction: The opening paragraph of your research proposal is, perhaps, the most important. Here you want to introduce the research problem in a creative way, and demonstrate your understanding of the need for the research. You want the reader to think that your proposed research is current, important and relevant.
• Background: Include a brief history of the topic and link it to a contemporary context to show its relevance for today. Identify key researchers and institutions also looking at the problem
• Literature Review: This is the section that may take the longest amount of time to assemble. Here you want to synthesize prior research, and place your proposed research into the larger picture of what’s been studied in the past. You want to show your reader that your work is original, and adds to the current knowledge.
• Research Design and Methodology: This section should be very clearly and logically written and organized. You are letting your reader know that you know what you are going to do, and how. The reader should feel confident that you have the skills and knowledge needed to get the project done.
• Preliminary Implications: Here you’ll be outlining how you anticipate your research will extend current knowledge in your field. You might also want to discuss how your findings will impact future research needs.
• Conclusion: This section reinforces the significance and importance of your proposed research, and summarizes the entire proposal.
• References/Citations: Of course, you need to include a full and accurate list of any and all sources you used to write your research proposal.

Common Mistakes in Writing a Scientific Research Project Proposal

Remember, the best research proposal can be rejected if it’s not well written or is ill-conceived. The most common mistakes made include:

• Not providing the proper context for your research question or the problem
• Failing to reference landmark/key studies
• Losing focus of the research question or problem
• Not accurately presenting contributions by other researchers and institutions
• Incompletely developing a persuasive argument for the research that is being proposed
• Misplaced attention on minor points and/or not enough detail on major issues
• Sloppy, low-quality writing without effective logic and flow
• Incorrect or lapses in references and citations, and/or references not in proper format
• The proposal is too long – or too short

Scientific Research Proposal Example

There are countless examples that you can find for successful research proposals. In addition, you can also find examples of unsuccessful research proposals. Search for successful research proposals in your field, and even for your target journal, to get a good idea on what specifically your audience may be looking for.

While there’s no one example that will show you everything you need to know, looking at a few will give you a good idea of what you need to include in your own research proposal. Talk, also, to colleagues in your field, especially if you are a student or a new researcher. We can often learn from the mistakes of others. The more prepared and knowledgeable you are prior to writing your research proposal, the more likely you are to succeed.

One of the top reasons scientific research proposals are rejected is due to poor logic and flow. Check out our Language Editing Services to ensure a great proposal , that’s clear and concise, and properly referenced. Check our video for more information, and get started today.

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Research in the Biological and Life Sciences: A Guide for Cornell Researchers: Literature Reviews

• Books and Dissertations
• Databases and Journals
• Locating Theses
• Resource Not at Cornell?
• Citing Sources
• Staying Current
• Measuring your research impact
• Plagiarism and Copyright
• Data Management
• Literature Reviews
• Evidence Synthesis and Systematic Reviews
• Writing an Honors Thesis
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• Research Help

What is a Literature Review?

A literature review is a body of text that aims to review the critical points of current knowledge on a particular topic. Most often associated with science-oriented literature, such as a thesis, the literature review usually proceeds a research proposal, methodology and results section. Its ultimate goals is to bring the reader up to date with current literature on a topic and forms that basis for another goal, such as the justification for future research in the area. (retrieved from  http://en.wikipedia.org/wiki/Literature_review )

Writing a Literature Review

The literature review is the section of your paper in which you cite and briefly review the related research studies that have been conducted. In this space, you will describe the foundation on which  your  research will be/is built. You will:

• discuss the work of others
• evaluate their methods and findings
• identify any gaps in their research
• state how  your  research is different

The literature review should be selective and should group the cited studies in some logical fashion.

If you need some additional assistance writing your literature review, the Knight Institute for Writing in the Disciplines offers a  Graduate Writing Service .

Demystifying the Literature Review

For more information, visit our guide devoted to " Demystifying the Literature Review " which includes:

• guide to conducting a literature review,
• a recorded 1.5 hour workshop covering the steps of a literature review, a checklist for drafting your topic and search terms, citation management software for organizing your results, and database searching.

Online Resources

• A Guide to Library Research at Cornell University
• Literature Reviews: An Overview for Graduate Students North Carolina State University 
• The Literature Review: A Few Tips on Conducting Written by Dena Taylor, Director, Health Sciences Writing Centre, and Margaret Procter, Coordinator, Writing Support, University of Toronto
• How to Write a Literature Review University Library, University of California, Santa Cruz
• Review of Literature The Writing Center, University of Wisconsin-Madison

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Yale undergraduate research, how to write a proposal.

The abstract should summarize your proposal. Include one sentence to introduce the problem you are investigating, why this problem is significant, the hypothesis to be tested, a brief summary of experiments that you wish to conduct and a single concluding sentence. (250 word limit)

Introduction

The introduction discusses the background and significance of the problem you are investigating. Lead the reader from the general to the specific. For example, if you want to write about the role that Brca1 mutations play in breast cancer pathogenesis, talk first about the significance of breast cancer as a disease in the US/world population, then about familial breast cancer as a small subset of breast cancers in general, then about discovery of Brca1 mutations in familial breast cancer, then Brca1’s normal functions in DNA repair, then about how Brca1 mutations result in damaged DNA and onset of familial breast cancer, etc. Definitely include figures with properly labeled text boxes (designated as Figure 1, Figure 2, etc) here to better illustrate your points and help your reader wade through unfamiliar science. (3 pages max)

Formulate a hypothesis that will be tested in your grant proposal. Remember, you are doing hypothesis-driven research so there should be a hypothesis to be tested! The hypothesis should be focused, concise and flow logically from the introduction. For example, your hypothesis could be “I hypothesize that overexpressing wild type Brca1 in Brca1 null tumor cells will prevent metastatic spread in a mouse xenograph model.” Based on your hypothesis, your Specific Aims section should be geared to support it. The hypothesis is stated in one sentence in the proposal. 

Specific Aims (listed as Specific Aim 1, Specific Aim 2)

This is where you will want to work with your mentor to craft the experimental portion of your proposal. Propose two original specific aims to test your hypothesis. Don’t propose more than two aims-you will NOT have enough time to do more. In the example presented, Specific Aim 1 might be “To determine the oncogenic potential of Brca1 null cell lines expressing wild type Brca1 cDNA”. Specific aim 2 might be “To determine the metastatic potential of Brca1 null cells that express WT Brca1”. You do not have to go into extensive technical details, just enough for the reader to understand what you propose to do. The best aims yield mechanistic insights-that is, experiments proposed address some mechanisms of biology. A less desirable aim proposes correlative experiments that does not address mechanistically how BRCA1 mutations generate cancer. It is also very important that the two aims are related but NOT interdependent. What this means is that if Aim 1 doesn’t work, Aim 2 is not automatically dead. For example, say you propose in Aim 1 to generate a BRCA1 knockout mouse model, and in Aim 2 you will take tissues from this mouse to do experiments. If knocking out BRCA1 results in early embryonic death, you will never get a mouse that yields tissues for Aim 2. You can include some of your mentor’s data here as “Preliminary data”. Remember to carefully cite all your sources. (4 pages max; 2 pages per Aim)

Potential pitfalls and alternative strategies

This is a very important part of any proposal. This is where you want to discuss the experiments you propose in Aims 1 and 2. Remember, no experiment is perfect. Are there any reasons why experiments you proposed might not work? Why? What will you do to resolve this? What are other possible strategies you might use if your experiments don’t work? If a reviewer spots these deficiencies and you don’t propose methods to correct them, your proposal will not get funded. You will want to work with your mentor to write this section. (1/2 page per Aim)

Cite all references, including unpublished data from your mentor. Last, First, (year), Title, Journal, volume, pages.

*8 page proposal limit (not including References), 1.5 spacing, 12pt Times New Roman font

• View an example of a research proposal submitted for the Yale College First-Year Summer Research Fellowship (PDF).  
• View an example of a research proposal submitted for the Yale College Dean’s Research Fellowship and the Rosenfeld Science Scholars Program (PDF) .

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Research Proposal Examples for Every Science Field

Looking for research funding can be a daunting task, especially when you are starting out. A great way to improve grant-writing skills is to get inspired by winning research proposal examples.

To assist you in writing a competitive proposal, I have curated a collection of real-life research proposal examples from various scientific disciplines. These examples will allow you to gain inspiration about the way research proposals are structured and written.

Structure of a Research Proposal

A research proposal serves as a road-map for a project, outlining the objectives, methodology, resources, and expected outcomes. The main goal of writing a research proposal is to convince funding agency of the value and feasibility of a research project. But a proposal also helps scientists themselves to clarify their planned approach.

While the exact structure may vary depending on the science field and institutional guidelines, a research proposal typically includes the following sections: Problem, Objectives, Methodology, Resources, Participants, Results&Impact, Dissemination, Timeline, and Budget. I will use this structure for the example research proposals in this article.

Here is a brief description of what each of the nine proposal sections should hold.

A concise and informative title that captures the essence of the research proposal. Sometimes an abstract is required that briefly summarizes the proposed project.

Clearly define the research problem or gap in knowledge that the study aims to address. Present relevant background information and cite existing literature to support the need for further investigation.

State the specific objectives and research questions that the study seeks to answer. These objectives should be clear, measurable, and aligned with the problem statement.

Methodology

Describe the research design, methodology, and techniques that will be employed to collect and analyze data. Justify your chosen approach and discuss its strengths and limitations.

Outline the resources required for the successful execution of the research project, such as equipment, facilities, software, and access to specific datasets or archives.

Participants

Describe the research team’s qualification for implementing the research methodology and their complementary value

Results and Impact

Describe the expected results, outcomes, and potential impact of the research. Discuss how the findings will contribute to the field and address the research gap identified earlier.

Dissemination

Explain how the research results will be disseminated to the academic community and wider audiences. This may include publications, conference presentations, workshops, data sharing or collaborations with industry partners.

Develop a realistic timeline that outlines the major milestones and activities of the research project. Consider potential challenges or delays and incorporate contingency plans.

Provide a detailed budget estimate, including anticipated expenses for research materials, equipment, participant compensation, travel, and other relevant costs. Justify the budget based on the project’s scope and requirements.

Consider that the above-mentioned proposal headings can be called differently depending on the funder’s requirements. However, you can be sure in one proposal’s section or another each of the mentioned sections will be included. Whenever provided, always use the proposal structure as required by the funding agency.

Research Proposal template download

This research proposal template includes the nine headings that we just discussed. For each heading, a key sentence skeleton is provided to help you to kick-start the proposal writing process.

Real-Life Research Proposal Examples

Proposals can vary from field to field so I will provide you with research proposal examples proposals in four main branches of science: social sciences, life sciences, physical sciences, and engineering and technology. For each science field, you will be able to download real-life winning research proposal examples.

To illustrate the principle of writing a scientific proposal while adhering to the nine sections I outlined earlier, for each discipline I will also provide you with a sample hypothetical research proposal. These examples are formulated using the key sentence structure that is included in the download template .

In case the research proposal examples I provide do not hold exactly what you are looking for, use the Open Grants database. It holds approved research proposals from various funding agencies in many countries. When looking for research proposals examples in the database, use the filer to search for specific keywords and organize the results to view proposals that have been funded.

Research Proposals Examples in Social Sciences

Here are real-life research proposal examples of funded projects in social sciences.

Here is an outline of a hypothetical Social Sciences research proposal that is structured using the nine proposal sections we discussed earlier. This proposal example is produced using the key sentence skeleton that you will access in the proposal template .

The Influence of Social Media on Political Participation among Young Adults

Social media platforms have become prominent spaces for political discussions and information sharing. However, the impact of social media on political participation among young adults remains a topic of debate.

With the project, we aim to establish the relationship between social media usage and political engagement among young adults. To achieve this aim, we have three specific objectives:

• Examine the association between social media usage patterns and various forms of political participation, such as voting, attending political rallies, and engaging in political discussions.
• Investigate the role of social media in shaping political attitudes, opinions, and behaviors among young adults.
• Provide evidence-based recommendations for utilizing social media platforms to enhance youth political participation.

During the project, a mixed methods approach, combining quantitative surveys and qualitative interviews will be used to determine the impact of social media use on youth political engagement. In particular, surveys will collect data on social media usage, political participation, and attitudes. Interviews will provide in-depth insights into participants’ experiences and perceptions.

The project will use survey software, transcription tools, and statistical analysis software to statistically evaluate the gathered results. The project will also use project funding for participant compensation.

Principal investigator, Jane Goodrich will lead a multidisciplinary research team comprising social scientists, political scientists, and communication experts with expertise in political science and social media research.

The project will contribute to a better understanding of the influence of social media on political participation among young adults, including:

• inform about the association between social media usage and political participation among youth.
• determine the relationship between social media content and political preferences among youth.
• provide guidelines for enhancing youth engagement in democratic processes through social media use.

We will disseminate the research results within policymakers and NGOs through academic publications in peer-reviewed journals, presentations at relevant conferences, and policy briefs.

The project will start will be completed within two years and for the first two objectives a periodic report will be submitted in months 12 and 18.

The total eligible project costs are 58,800 USD, where 15% covers participant recruitment and compensation, 5% covers survey software licenses, 55% are dedicated for salaries, and 25% are intended for dissemination activities.

Research Proposal Examples in Life Sciences

Here are real-life research project examples in life sciences.

Here is a hypothetical research proposal example in Life Sciences. Just like the previous example, it consists of the nine discussed proposal sections and it is structured using the key sentence skeleton that you will access in the proposal template .

Investigating the Role of Gut Microbiota in Obesity and Metabolic Syndrome (GUT-MET)

Obesity and metabolic syndrome pose significant health challenges worldwide, leading to numerous chronic diseases and increasing healthcare costs. Despite extensive research, the precise mechanisms underlying these conditions remain incompletely understood. A critical knowledge gap exists regarding the role of gut microbiota in the development and progression of obesity and metabolic syndrome.

With the GUT-MET project, we aim to unravel the complex interactions between gut microbiota and obesity/metabolic syndrome. To achieve this aim, we have the following specific objectives:

• Investigate the composition and diversity of gut microbiota in individuals with obesity and metabolic syndrome.
• Determine the functional role of specific gut microbial species and their metabolites in the pathogenesis of obesity and metabolic syndrome.

During the project, we will employ the following key methodologies:

• Perform comprehensive metagenomic and metabolomic analyses to characterize the gut microbiota and associated metabolic pathways.
• Conduct animal studies to investigate the causal relationship between gut microbiota alterations and the development of obesity and metabolic syndrome.

The project will benefit from state-of-the-art laboratory facilities, including advanced sequencing and analytical equipment, as well as access to a well-established cohort of participants with obesity and metabolic syndrome.

Dr. Emma Johnson, a renowned expert in gut microbiota research and Professor of Molecular Biology at the University of PeerRecognized, will lead the project. Dr. Johnson has published extensively in high-impact journals and has received multiple research grants focused on the gut microbiota and metabolic health.

The project will deliver crucial insights into the role of gut microbiota in obesity and metabolic syndrome. Specifically, it will:

• Identify microbial signatures associated with obesity and metabolic syndrome for potential diagnostic and therapeutic applications.
• Uncover key microbial metabolites and pathways implicated in disease development, enabling the development of targeted interventions.

We will actively disseminate the project results within the scientific community, healthcare professionals, and relevant stakeholders through publications in peer-reviewed journals, presentations at international conferences, and engagement with patient advocacy groups.

The project will be executed over a period of 36 months. Key milestones include data collection and analysis, animal studies, manuscript preparation, and knowledge transfer activities.

The total eligible project costs are $1,500,000, with the budget allocated for 55% personnel, 25% laboratory supplies, 5% data analysis, and 15% knowledge dissemination activities as specified in the research call guidelines.

Research Proposals Examples in Natural Sciences

Here are real-life research proposal examples of funded projects in natural sciences.

Here is a Natural Sciences research proposal example that is structured using the same nine sections. I created this proposal example using the key sentence skeleton that you will access in the proposal template .

Assessing the Impact of Climate Change on Biodiversity Dynamics in Fragile Ecosystems (CLIM-BIODIV)

Climate change poses a significant threat to global biodiversity, particularly in fragile ecosystems such as tropical rainforests and coral reefs. Understanding the specific impacts of climate change on biodiversity dynamics within these ecosystems is crucial for effective conservation and management strategies. However, there is a knowledge gap regarding the precise mechanisms through which climate change influences species composition, population dynamics, and ecosystem functioning in these vulnerable habitats.

With the CLIM-BIODIV project, we aim to assess the impact of climate change on biodiversity dynamics in fragile ecosystems. To achieve this aim, we have the following specific objectives:

• Investigate how changes in temperature and precipitation patterns influence species distributions and community composition in tropical rainforests.
• Assess the effects of ocean warming and acidification on coral reef ecosystems, including changes in coral bleaching events, species diversity, and ecosystem resilience.
• Conduct field surveys and employ remote sensing techniques to assess changes in species distributions and community composition in tropical rainforests.
• Utilize experimental approaches and long-term monitoring data to evaluate the response of coral reefs to varying temperature and pH conditions.

The project will benefit from access to field sites in ecologically sensitive regions, advanced remote sensing technology, and collaboration with local conservation organizations to facilitate data collection and knowledge sharing.

Dr. Alexander Chen, an established researcher in climate change and biodiversity conservation, will lead the project. Dr. Chen is a Professor of Ecology at the University of Peer Recognized, with a track record of three Nature publications and successful grant applications exceeding 25 million dollars.

The project will provide valuable insights into the impacts of climate change on biodiversity dynamics in fragile ecosystems. It will:

• Enhance our understanding of how tropical rainforest communities respond to climate change, informing targeted conservation strategies.
• Contribute to the identification of vulnerable coral reef ecosystems and guide management practices for their protection and resilience.

We will disseminate the project results to the scientific community, conservation practitioners, and policymakers through publications in reputable journals, participation in international conferences, and engagement with local communities and relevant stakeholders.

The project will commence on March 1, 2024, and will be implemented over a period of 48 months. Key milestones include data collection and analysis, modeling exercises, stakeholder engagement, and knowledge transfer activities. These are summarized in the Gantt chart.

The total eligible project costs are $2,000,000, with budget allocation for research personnel, fieldwork expenses, laboratory analyses, modeling software, data management, and dissemination activities.

Research Proposal Examples in Engineering and Technology

Here are real-life research proposal examples of funded research projects in the field of science and technology.

Here is a hypothetical Engineering and Technology research proposal example that is structured using the same nine proposal sections we discussed earlier. I used the key sentence skeleton available in the proposal template to produce this example.

Developing Sustainable Materials for Energy-Efficient Buildings (SUST-BUILD)

The construction industry is a major contributor to global energy consumption and greenhouse gas emissions. Addressing this issue requires the development of sustainable materials that promote energy efficiency in buildings. However, there is a need for innovative engineering solutions to overcome existing challenges related to the performance, cost-effectiveness, and scalability of such materials.

With the SUST-BUILD project, we aim to develop sustainable materials for energy-efficient buildings. Our specific objectives are as follows:

• Design and optimize novel insulating materials with enhanced thermal properties and reduced environmental impact.
• Develop advanced coatings and surface treatments to improve the energy efficiency and durability of building envelopes.
• Conduct extensive material characterization and simulation studies to guide the design and optimization of insulating materials.
• Utilize advanced coating techniques and perform full-scale testing to evaluate the performance and durability of building envelope treatments.

The project will benefit from access to state-of-the-art laboratory facilities, including material testing equipment, thermal analysis tools, and coating application setups. Collaboration with industry partners will facilitate the translation of research findings into practical applications.

Dr. Maria Rodriguez, an experienced researcher in sustainable materials and building technologies, will lead the project. Dr. Rodriguez holds a position as Associate Professor in the Department of Engineering at Peer Recognized University and has a strong publication record and expertise in the field.

The project will deliver tangible outcomes for energy-efficient buildings. It will:

• Develop sustainable insulating materials with superior thermal performance, contributing to reduced energy consumption and greenhouse gas emissions in buildings.
• Introduce advanced coatings and surface treatments developed from sustainable materials that enhance the durability and energy efficiency of building envelopes, thereby improving long-term building performance.

We will disseminate project results to relevant stakeholders, including industry professionals, architects, and policymakers. This will be accomplished through publications in scientific journals, presentations at conferences and seminars, and engagement with industry associations.

The project will commence on September 1, 2024, and will be implemented over a period of 36 months. Key milestones include material development and optimization, performance testing, prototype fabrication, and knowledge transfer activities. The milestones are summarized in the Gantt chart.

The total eligible project costs are $1,800,000. The budget will cover personnel salaries (60%), materials and equipment (10%), laboratory testing (5%), prototyping (15%), data analysis (5%), and dissemination activities (5%) as specified in the research call guidelines.

Final Tips for Writing an Winning Research Proposal

Come up with a good research idea.

Ideas are the currency of research world. I have prepared a 3 step approach that will help you to come up with a research idea that is worth turning into a proposal. You can download the Research Idea Generation Toolkit in this article.

Start with a strong research outline

Before even writing one sentence of the research proposal, I suggest you use the Research Project Canvas . It will help you to first come up with different research ideas and then choose the best one for writing a full research proposal.

Tailor to the requirements of the project funder

Treat the submission guide like a Monk treats the Bible and follow its strict requirements to the last detail. The funder might set requirements for the topic, your experience, employment conditions, host institution, the research team, funding amount, and so forth. 

What you would like to do in the research is irrelevant unless it falls within the boundaries defined by the funder.

Make the reviewer’s job of finding flaws in your proposal difficult by ensuring that you have addressed each requirement clearly. If applicable, you can even use a table with requirements versus your approach. This will make your proposed approach absolutely evident for the reviewers.

Before submitting, assess your proposal using the criteria reviewers have to follow.

Conduct thorough background research

Before writing your research proposal, conduct comprehensive background research to familiarize yourself with existing literature, theories, and methodologies related to your topic. This will help you identify research gaps and formulate research questions that address these gaps. You will also establish competence in the eyes of reviewers by citing relevant literature.

Be concise and clear

Define research questions that are specific, measurable, and aligned with the problem statement.

If you think the reviewers might be from a field outside your own, avoid unnecessary jargon or complex language to help them to understand the proposal better.

Be specific in describing the research methodology. For example, include a brief description of the experimental methods you will rely upon, add a summary of the materials that you are going to use, attach samples of questionnaires that you will use, and include any other proof that demonstrates the thoroughness you have put into developing the research plan. Adding a flowchart is a great way to present the methodology.

Create a realistic timeline and budget

Develop a realistic project timeline that includes key milestones and activities, allowing for potential challenges or delays. Similarly, create a detailed budget estimate that covers all anticipated expenses, ensuring that it aligns with the scope and requirements of your research project. Be transparent and justify your budget allocations.

Demonstrate the significance and potential impact of the research

Clearly articulate the significance of your research and its potential impact on the field. Discuss how your findings can contribute to theory development, practical applications, policy-making, or other relevant areas.

Pay attention to formatting and style guidelines

Follow the formatting and style guidelines provided by your institution or funding agency. Pay attention to details such as font size, margins, referencing style, and section headings. Adhering to these guidelines demonstrates professionalism and attention to detail.

Take a break before editing

After preparing the first draft, set it aside for at least a week. Then thoroughly check it for logic and revise, revise, revise. Use the proposal submission guide to review your proposal against the requirements. Remember to use grammar checking tools to check for errors.

Finally, read the proposal out loud. This will help to ensure good readability.

Seek feedback

Share your proposal with mentors, colleagues, or members of your research community to receive constructive feedback and suggestions for improvement. Take these seriously since they provide a third party view of what is written (instead of what you think you have written).

Reviewing good examples is one of the best ways to learn a new skill. I hope that the research proposal examples in this article will be useful for you to get going with writing your own research proposal.

Have fun with the writing process and I hope your project gets approved!

Learning from research proposal examples alone is not enough

The research proposal examples I provided will help you to improve your grant writing skills. But learning from example proposals alone will take you a rather long time to master writing winning proposals.

To write a winning research proposal, you have to know how to add that elusive X-Factor that convinces the reviewers to move your proposal from the category “good” to the category “support”. This includes creating self-explanatory figures, creating a budget, collaborating with co-authors, and presenting a convincing story.

To write a research proposal that maximizes your chances of receiving research funding, read my book “ Write a Winning Research Proposal “.

This isn’t just a book. It’s a complete research proposal writing toolkit that includes a  project ideation canvas, budget spreadsheet, project rating scorecard, virtual collaboration whiteboard, proposal pitch formula, graphics creation cheat sheet, review checklist and other valuable resources that will help you succeed.

Hey! My name is Martins Zaumanis and I am a materials scientist in Switzerland ( Google Scholar ). As the first person in my family with a PhD, I have first-hand experience of the challenges starting scientists face in academia. With this blog, I want to help young researchers succeed in academia. I call the blog “Peer Recognized”, because peer recognition is what lifts academic careers and pushes science forward.

Besides this blog, I have written the Peer Recognized book series and created the Peer Recognized Academy offering interactive online courses.

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Hi Martins, I’ve recently discovered your content and it is great. I will be implementing much of it into my workflow, as well as using it to teach some graduate courses! I noticed that a materials science-focused proposal could be a very helpful addition.

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Writing a Theoretical Research Proposal Bioscene 17 Engaging Biology Undergraduates in the Scientific Process Through Writing a Theoretical Research Proposal

Abstract: It has been suggested that research experiences are an important element that should be included in all undergraduate Biology curricula. This is a difficult suggestion to accommodate due to issues with cost, space and time. We addressed this challenge through development of a capstone project in which Biology majors work in groups to develop novel theoretical research proposals with guidance from a faculty mentor. Though students are not directly working at the bench, they are being mentored in aspects of the scientific process such as synthesizing information from the literature, asking novel research questions, constructing logical aims, designing experiments and writing scientifically. Since this project began, we have mentored 417 students in proposal writing and have assessed their experiences through pre- and post-surveys. Students have made gains in several areas, but most notably in their ability to pose novel questions and develop an experimental plan, and in the ...

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This article reports on a one-semester Advanced Cell Biology course that endeavors to bridge the gap between gaining basic textbook knowledge about cell biology and learning to think and work as a researcher. The key elements of this course are 1) learning to work with primary articles in order to get acquainted with the field of choice, to learn scientific reasoning, and to identify gaps in our current knowledge that represent opportunities for further research; 2) formulating a research project with fellow students; 3) gaining thorough knowledge of relevant methodology and technologies used within the field of cell biology; 4) developing cooperation and leadership skills; and 5) presenting and defending research projects before a jury of experts. The course activities were student centered and focused on designing a genuine research program. Our 5-yr experience with this course demonstrates that 1) undergraduate students are capable of delivering high-quality research designs that...

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As part of a wider reform to scaffold quantitative and research skills throughout the biology major, we introduced course-based undergraduate research experiences (CURE) in sections of a large-enrollment introductory biology laboratory course in a mid-level, public, minority-serving institution. This initiative was undertaken as part of the in the National Science Foundation / Council for Undergraduate Research Transformations Project. Student teams performed two or three experiments, depending on semester. They designed, implemented, analyzed, revised and iterated, wrote scientific paper-style reports, and gave oral presentations. We tested the impact of CURE on student proficiency in experimental design and statistical reasoning, and student research confidence and attitudes over two semesters. We found that students in the CURE sections met the reformed learning objectives for experimental design and statistical reasoning. CURE students also showed higher levels of experimental d...

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Participation in research provides personal and professional benefits for undergraduates. However, some students face institutional barriers that prevent their entry into research, particularly those from underrepresented groups who may stand to gain the most from research experiences. Course-based undergraduate research experiences (CUREs) effectively scale research availability, but many only last for a single semester, which is rarely enough time for a novice to develop proficiency. To address these challenges, we present the Pipeline CURE, a framework that integrates a single research question throughout a biology curriculum. Students are introduced to the research system-in this implementation, C. elegans epigenetics research-with their first course in the major. After revisiting the research system in several subsequent courses, students can choose to participate in an upper-level research experience. In the Pipeline, students build resilience via repeated exposure to the same research system. Its iterative, curriculum-embedded approach is flexible enough to be implemented at a range of institutions using a variety of research questions. By uniting evidence-based teaching methods with ongoing scientific research, the Pipeline CURE provides a new model for overcoming barriers to participation in undergraduate research.

CBE—Life Sciences Education

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Allen Schoffstall

In: Shaping the Future of Biological Education Research: Selected Papers from the ERIDOB 2022 Conference, Korfiatis, K., Grace, M. & Hammann, M. (Eds), Springer, Cham, pp. 107-117.

Michael J Reiss , Wilton Lodge

School biology often entails undertaking practical work, which is generally intended to help students gain conceptual understanding, practical and wider skills, and understanding of how biologist work (Kampourakis & Reiss, 2018). However, the literature on practical work in school science indicates that it often achieves less than its proponents intend (Abrahams & Millar, 2008; Gatsby Charitable Foundation, 2017). Investigative school research projects are relatively uncommon, relative to other types of practical work, such as confirmatory practical activities (intended to produce the same result for all students every time), but it has been argued that they can give students a better understanding of what it is like to undertake authentic science. A systematic review found that investigative student science research projects could have a number of benefits for students including the learning of science ideas, affective responses to science, intentions to pursue careers involving science, and development of a range of skills, some specific to practical work and others, such as collaborative teamwork, more general (Bennett et al., 2018). Nevertheless, this same review concluded that further work is needed to enhance the quality of the available evidence and to explore more fully the potential longer-term benefits of participation in such projects at secondary school level.

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Thesis proposal example 2

Senior Honors Thesis Research Proposal

Albert B. Ulrich III Thesis Advisor: Dr. Wayne Leibel 11 September 1998

Introduction:

Neotropical fish of the family Cichlidae are a widespread and diverse group of freshwater fish which, through adaptive radiation, have exploited various niches in freshwater ecosystems. One such evolutionary adaptation employed by numerous taxa is miniaturization, an evolutionary process in which a large ancestral form becomes reduced in size to exploit alternative niches. A considerable amount of research has been conducted on the effects of miniaturization on amphibians (Hanken 1983), but although miniaturization has been found to occur in 85 species of freshwater South American fish, little has been done to investigate the effects which miniaturization imposes on the anatomy of the fish (Hanken and Wake 1993).

Background:

Evolution is the process by which species adapt to environmental stresses over time. Nature imposes various selective pressures on ecosystems causing adaptive radiation, where species expand and fill new niches. One such adaptation for a new niche is miniaturization. Miniaturization can be defined as “the evolution of extremely small adult body size within a lineage” (Hanken and Wake 1993). Miniaturization is observed in a variety of taxa, and evolutionary size decreases are observed in mammals and higher vertebrates, but it is more common and more pronounced in reptiles, amphibians and fish (Hanken and Wake 1993). Miniaturization evolved as a specialization which allowed the organisms to avoid selective pressures and occupy a new niche. Miniaturization as a concept is dependent on the phylogenetic assumption that the organism evolved from a larger predecessor. Over time, the miniature organism had to adapt to the new conditions as a tiny species. All of the same basic needs had to be met, but with a smaller body.

In miniature species there is a critical relationship between structure of the body and body size, and frequently this downsizing results in structural and functional changes within the animal (Harrison 1996). Within the concept of miniaturization is the assumption that the species evolved from a larger progenitor. It is necessary then to explore the effects of the miniaturization process. “Miniaturization involves not only small body size per se, but also the consequent and often dramatic effects of extreme size reduction on anatomy, physiology, ecology, life history, and behavior” (Hanken and Wake 1993).

Hanken and Wake 1993 found that the adult skulls of the salamander Thorius were lacking several bones, others were highly underdeveloped, and many species within the genus were toothless. Several invertebrate species display the wholesale loss of major organs systems as a result of the drastic reduction in body size (Hanken and Wake 1993). Hanken and Wake also have shown that morphological novelty is a common result of miniaturization. Morphological novelty, in essence, is the development of new structures in the miniature organism. For example, as body size decreases, certain vital organs will only be able to be reduced by a certain amount and still function. As a result organs such as the inner ear remain large relative to the size of the miniature skull, and structural innovations have to occur in order to support the proportionately large inner ear.

In 1983, James Hanken, at the University of Colorado determined that the adult skull of the Plethodontid salamanders could be characterized by three observations: 1) there was a limited development or even an absence of several ossified elements such as dentition and other bones; 2) there was interspecific and intraspecific variability; 3) there were novel mophological configurations of the braincase and jaw (Hanken 1983).

In his experiments, Hanken found that cranial miniaturization of the Thorius skull was achieved at the expense of ossification. Much of the ossified skeleton was lost or reduced, especially in the anterior elements, which are seen typically in larger adult salamanders (Hanken 1983). In contrast to this ossified downsizing, many of the sensory organs were not diminished in size — therefore present in greater proportion to the rest of the reduced head. He also reported that due to the geometrical space availability, there is a competition for space in reduced sized skulls, and the “predominant brain, otic capsules, and eyes have imposed structural rearrangements on much of the skull that remains” (Hanken 1983).

Hanken proposed that paedomorphosis was the mode of evolution of the plethodontid salamanders (Hanken 1983). Paedomorphosis is the state where the miniaturized structures of the adult salamanders can be described as arrested juvenile states. To support this theory, Hanken showed data where cranial skeletal reduction was less extreme in the posterior regions of the skull. One of the hallmarks of paedamorphosis is the lack of conservation in structures derived late in development. Early developed structures are highly conserved, and the latter derivations become either lost, or greatly reduced. Again, Hanken has shown that elements appearing late in development exhibit greater variation among species than do elements appearing earlier in ontogeny (Hanken 1983). But the presence of novel morphological features cannot be accounted for merely by truncated development and the retention of juvenile traits. Miniature Plethodontid salamanders display features that are not present in other species, juvenile or adult. These novel morphological features are associated with the evolution of decreased size and are postulated to compensate for the reductions occurring in other areas (Hanken 1983).

In 1985, Trueb and Alberch published a paper presenting similar results in their experiments with frogs. They explored the “relationships between body sizes of anurans and their cranial configurations with respect to the degree of ossification of the skull and two ontogenetic variables‹shape and number of differentiation events” (Trueb and Alberch 1985). Trueb and Alberch examined three morphological variables: size, sequence of differentiation events, and shape changes in individual structures. Size and snout length were measured, and the data showed that the more heavily ossified frogs tended to be smaller, whereas the less-ossified species were of average size, contrary to what was hypothesized. But Trueb and Alberch also attributed the diminution in size to paedomorphosis, citing that the smaller frogs lacked one or more of the elements typically associated with anuran skulls‹these missing elements were typically late in the developmental sequence. It is significant to note, however, that although there was an apparent paedomorphic trend, it could not be “applied unequivocally to all anuans” (Trueb and Alberch 1985). Very little research has been done on the effects of miniaturization on fish. In 1993, Buckup published a paper discussing the phylogeny of newly found minature species of Characidiin fish, but the extent of the examination was merely an acknowledgment that the species were indeed miniatures so that they could be taxonomically reclassified ( Buckup 1993). It is this deficit of knowledge with regard to miniaturization in fish that prompts this research.

Statement of the Problem:

How does miniaturization affect other vertebrates, such as fish? There are over 85 species of freshwater South American fish which are regarded as miniature, spanning 5 orders, 11 families and 40 genera (Hanken and Wake 1993). One such species, Apistogramma cacatuoides, is a South American Cichlid native to Peru. It lives in shallow water bodies in the rainforests, where miniature size is necessary. Males in this species reach approximately 8cm, and females only 5cm. This makes A. cacatuoides an ideal specimen for examination. In this senior honors thesis, I intend to examine the effects of miniaturization on cranial morphology of A. cacatuoides.

Plan of Research:

In this thesis, I will compare the cranial anatomy of A. cacatuoides to that of “Cichlasoma” (Archocentrus) nigrofasciatum, a commonly bred fish reared by aquarists known as the Convict Cichlid, a “typical” medium-sized cichlid also of South American origin. The Convicts will be examined at various stages in development, from juvenile to adult, and will be compared to A.cacatuoides.

The first part of this project will involve whole mount preparation of A. cacatuoides, utilizing the staining and clearing procedures described by Taylor and Van Dyke, 1985. This procedure involves the use of Alizarin Red and Alcian Blue to stain bone and cartilage, and takes into account the adaptations and recommendations Proposed in an earlier paper (Hanken and Wassersug 1981). The Taylor and Van Dyke procedure is specifically for the staining and clearing of small fish and other vertebrates. I tested the procedure during last semester¹s Independent Study and made a few minor adjustments to the protocol.

First, the specimens will be placed serially into an absolute ethyl alcohol solution and stained with Alcian Blue. The fish will then be neutralized in a saturated borax solution, transferred to a 20% hydrogen peroxide solution in potassium hydroxide, and then bleached under a fluorescent light. The unwanted soft tissues will then be cleared using trypsin powder, and then stained in KOH again with alizarin red. The final preparation of the fish involves rinsing the fish, and placing them serially into 40%, 70%, and finally 100% glycerin.

Following the above preparation of the specimens, the crania of the A. cacatuoides specimens will be examined for morphological variation and compared to the cranial anatomy of the Convict cichlid as a progenitor reference point examined at various developmental stages to see if paedomorphosis in indeed the mechanism of miniaturization in A. cacatuoides.

Expected Costs:

The project is estimated to cost no more that five hundred dollars for chemicals and supplies for the entire year.

Literature Cited:

Hanken, J., 1983. Miniaturization and its Effects on Cranial Morphology in Plethodontid Salamanders, Genus Thorius (Amphibia: Plethodontidae). I. Osteological Variation”. Biological Journal of the Linnean Society (London) 23: 55-75.

Hanken, James, 1983. Miniaturization and its Effects on Cranial Morhology in Plethodontid Salamanders, Genus Thorius (Amphibia, Plethodintidae): II.The Fate of the Brain and Sense Organs and Their Role in Skull Morphogenesis and Evolution . Journal of Morphology 177: 255-268.

Hanken, James and David Wake, 1993. Miniaturization of Body Size: Origanismal Consequences and Evolutionary Significance. Annual Review of Ecological Systems 24: 501-19.

Harrison, I. J., 1996. Interface Areas in Small Fish. Zoological Symposium No. 69. The Zoological Society of London: London.

Miller, P. J., 1996. Miniature Vertebrates: The Implications of Small Body Size. Symposium of the Zoological Society of London. No. 69: 15-45.

Taylor, William R. and George Van Dyke, 1985. Revised Procedures for Staining and Clearing Small Fishes and Other Vertebrates for Small Bone and Cartilage Study. Cybium. 9(2): 107-119.

Trueb, L. and P. Alberch, 1985. Miniaturization and the Anuran Skull: a Case Study of Heterochrony. Fortschritte der Zoologie. Bund 30.

Williams, T. Walley, 1941 Bone and Cartilage. Stain. Tech. 16:23-25.

BIO 106: Environmental Biology

• Intro to the Research Process
• Develop a Topic
• Build a Search Plan
• Find Sources
• Class Activity: Source Type

Basic Search Tips

• Developing a Search Plan
• Identifying Search Terms
• Selecting Search Tools

Before you start searching for information, take time to plan your search strategy. This is a crucial stage of the research process as:

• It will save you time
• Your searching will be more structured
• Your search results will be more relevant

When you start out, you may feel overwhelmed by the breadth of information available. However, by planning your searches in advance and applying effective search techniques, you will find the most relevant content for your needs.

This worksheet will help you create your search plan. Break your topic into it's key concepts, brainstorm alternative search terms, and identify the best databases for research on this topic. 

• Developing a Search Strategy Worksheet Use this worksheet to help you identify concepts and key words to build successful searches.

You've selected your topic and done some background research, now it's time to think about searching. Before you jump into a database and run searches, take some time to build a searching plan. The first step of building a search plan is to identify potential search terms.

This short video introduces you to keyword searching.

Searching in Academic Search Complete

Watch this introductory video on searching for articles in the database, Academic Search Complete. Academic Search Complete is a general purpose resource that is a great place to start for any research topic.

• Academic Search Complete This link opens in a new window This database is a great place to get started with your research! It is a multidisciplinary database containing full-text articles from academic journals, popular magazines, and newspapers.
• << Previous: Develop a Topic
• Next: Find Sources >>
• Last Updated: Sep 13, 2024 3:21 PM
• URL: https://libguides.uis.edu/c.php?g=1423693

Verify originality of an essay

Get ideas for your paper

Cite sources with ease

200+ Fascinating Biology Research Topics for Students in 2024

Updated 03 Sep 2024

Biology is a vast and fascinating field that offers numerous opportunities for research and discovery. For students beginning their exploration in this area, selecting the right topic can be both exciting and challenging. Easy biology research topics provide accessible and manageable subjects that are engaging and relevant, ensuring that students at various academic levels feel encouraged and guided in their research endeavors. By choosing easy biology research topics, students can build a strong foundation and gain confidence as they delve deeper into the complexities of biological sciences.

Finding a great topic for a study can be challenging. Interesting biology topics need to be appealing, attention-grabbing and academically relevant. They need to deal with the recent findings and debatable questions. A great topic is a base of a scientific argument that has a valuable idea for the science. It also should provoke further discussion and lead to further coming studies.

College students have a hard time choosing the fascinating subject for their paper. That’s why these biology research paper topics can give you inspiration. You can pick one for your research or use them as the base for building your own idea.

Read also:  How to Write an Introduction to a Research Paper

A List of Researchable Topics for Biology 

A list of researchable topics for biology students starts with several interesting biological topics concerning sociological perspective and ethical issues. The most debatable subjects are abortion, human cloning, genetic research, and the new ethics that should be created to resolve these issues.

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• Customized writing: 100% original, personalized content.
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What are some good biology research topics?

One could also find good research topics related to traditional biology subfields like plant and animal biology, ecology (current global problems warrant a number of hot topics), or topics related to humans: neurobiology (and determinants of human behavior), recent discoveries on diseases and the immune system, etc.

What are the major biological issues today?

They include pollution challenges, overpopulation, an increase in infectious diseases, and the lack of transparency in DNA and synthetic biology studies. We also have biological issues like global warming, endangered species, stem cell research, and the acidification of the ocean. Stem cells hold significant potential in regenerative medicine by stimulating tissue and organ regeneration, but their use also raises important ethical considerations.

Read also: How can I find a trusted service to write my research paper ?

Biology Research Topics for College Students

When you choose a competitive Biology subject, you must focus on ideas that inspire you and talk about morphology, physiology, cell studies, origins, distribution, and innovations related to living organisms. Stem cells play a crucial role in medical applications and tissue regeneration, offering potential in stimulating the regeneration of tissues and organs. Human health is a crucial area of study, particularly focusing on the gut microbiome and its impact on overall health. You can also talk about the plants, the animals, or even famous personalities in the field.

• Developmental Biology and Aging: Exploring New Discoveries in Lifespan Extension Research
• The Role of Microbiomes in Ecosystem Health: A Look into the Microscopic Regulators of Ecological Balance
• CRISPR and Beyond: Advanced Genetic Editing Techniques Emerging in 2023
• Bioengineering and Sustainability: Harnessing Synthetic Biology for a Greener Future
• Revolutionizing Drug Discovery with Synthetic Biology: Progress and Prospects in 2023
• Challenges and Ethical Implications of Synthetic Biology: A Thorough Discussion on Genetically Modified Organisms
• The Use of The Advanced X-Ray for The Scanning of The Plants
• The Pros and Cons of The Cryo-EM Pattern in Virology
• The Use of 3D Models for The Microscopic Examination of Living Cells
• The Heritage of Jose Rizal and The Experiments Related to The Garden in Dapitan
• Understanding the Role of Epigenetics in Human Development: Current Research and Perspectives
• Heredity and Genetics Through The Lens of Autism: The Theories
• Novel Approaches to Conservation: How Modern Ecological Research Aids in Species Preservation
• Genetic Engineering and The Modern Survival of Life Mechanisms
• How Can The Energy Be Transformed Into Living Things
• Immune System of The Dolphins Compared to The Whales
• Primary Productivity in a Limited Ecosystem: The Role of The Social Community
• The Production of Hormones Without an Endocrine System: The Metabolism of The Plants

Abortion, Human cloning, Genetic Researches Biology Topics

• Presentation on Abortion Law & Society’s Perspective in the USA
• How Abortion is Related to the Feminist Ideology
• The Biological Insights of Abortion
• Human Cloning & Transplantation Possibilities
• Project on Different Types of Cloning
• DNA Structure, Genetic Disorders, and Modern Technology
• History and Development of Human Cloning Science
• Cloning: The Moral Aspect
• How Cloning Can Change Medicine
• What We Actually Know About DNA-modified Organisms
• The Influence of Genetics on Disease Susceptibility: Current Research in Personalized Medicine
• Genetic Grounds for Obesity
• Is Homosexuality Genetically Based?
• How Addictive Substances Affect Our Genes
• Depression & Genes
• Are Genetically Modified Foods Safe?
• Should Human Cloning Be Legal?
• The Advantages of Transgenic Crops
• Factors Contributing to Genetic Mutations
• Organ Transplantation: Is Donor’s Consent Needed?
• Ethics Behind Transplantation
• How Public Opinion Holds Back the Scientific Progress

DNA Research Topics

• The Pros and Cons of Family Genetic Testing: Mental Implications and The Abuse of Data
• Unraveling the Secrets of Junk DNA: New Insights into Non-Coding Regions and Their Roles
• Structured Controversy of DNA Alterations: What Ethical Principles Must be Followed
• Should DNA Alternation be Made Available when no Genetic Diseases are Involved?
• Inhibitors of Bacterial DNA and Resistance Mechanisms
• Bio-nano Technologies and The Covid-19 Pandemic: What Have We Learned
• Should DNA Research be Conducted on Animals and Plants: The Dangers Ahead
• Various Genetic Diseases and The Use of DNA Sequencing
• The Pros and Cons of The Protein-coding Approach to Regulatory Regions
• An Ethical Side of Selective Breeding and Damage to Reproductive Technologies
• Embryo Screening and Cloning: The Bioethical Aspect of Research
• DNA Modifications in Humans
• Can DNA Change Beat Aging?

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Behaviour and Hormones Biology Research Topics

Another huge part of biology research essay topics deals with the question of behavior and hormones. Students can share ideas on how our hormones influence mood and well-being. They can also be related to some disorders.

• Report on the Significance of Certain Hormones Concerning the Body Functioning
• Cell Structure & Antibiotic Resistance
• Hormones Influence on Mind and Behavior
• How Hormones Contribute to Depression
• Hormonal Changes During Pregnancy
• Psychological Disorders: The Biological Basis
• Biology Behind the Bipolar Disorder
• Cortisol and Testosterone Influence Risk-Taking
• Current Oxytocin Science
• Oxytocin and Fear Reaction
• Endocrine-Related Diseases
• How Hormones Affect Human Behavior
• Hormonal Control of Reproductive System
• Influence of Hormonal Therapy
• Endocrinology and Metabolism
• Hormone-Specific Psychopathic Disorders
• Melatonin in Therapy
• Steroid Hormones’ Path to Cells
• Cardio Exercise Influence Hormones
• Oxytocin in Treatment Psychopathic Disorders
• How Hormones Influence Women’s Mental Health
• Gender Specifics Related to Mental Health

Read also: 100 The Most Impressive Social Issues Topics for Essay or Paper

Immune System Biology Research Topics

Biology topics to write about cannot be full without at least several ones dealing with the immune system. It is our main defense against different diseases, that’s why it is important to know more about it.

• Human Immune System and Its Resistance Capabilities
• How Do Immune System Agents Function?
• Discovering Diseases Caused by Immune System not Functioning Good
• Immunity & Stress
• Tolerance & Autoimmunity
• Asthma & Allergic Reactions
• Immunotherapy Influence on Human Body
• Immunology & Transplantation
• Graft Rejection Prevention
• Vaccination: Are There Any Real Benefits?
• The Society’s Perspective on Vaccination

Cell Biology Research Topics

It is a complex branch of biology that studies the smallest units and the living organisms. Stem cells have the remarkable ability to differentiate into specific cell types for various medical applications. Uncontrolled cell growth is a critical area of study in understanding and treating cancer. The focus is on the parts of the cell and the interaction of the cytoplasm and the membrane as the topic ideas below show:

• The Pros And Cons Of The Cytoskeleton System Through The Lens Of Cell Motility.
• Investigating Cellular Dynamics in Early Human Development: Cutting Edge Techniques and Discoveries in 2023.
• Analysis Of Cell Division And The AI-based Methods Of Cell Cycle Control.
• The Role Of Chromatin In The Alterations Of Gene Expression.
• What Causes Cellular Metabolism In Marine Mammals.
• The Use Of Hormone Action Therapy In College Athletics.
• The Most Common Cell Infections And The Immunity Challenges.
• The Alteration Of Ribosomes And The Cell Membrane Functioning.
• The Heritage Of Robert Brown And The Nucleus.
• The Importance Of The Cork Tree Cell For Cell Biology.
• Analysis Of Multicellular Organisms And The Use Of Molecular Analysis Tools.

Molecular Biology Research Topics

The branch of Molecular Biology focuses on the analysis of composition, structure, and complex interactions related to processes taking place in the cells. Unlike basic microbiology, it studies biological processes like alteration, recreation, and maintenance.

• The Use Of Comparative Genomics Of The Human Being And The Mice.
• The Restrictions Of The DNA And Peculiarities Of The Modern Nucleic Acid Analysis.
• An Ethical Aspect Of Molecular Genetics.
• The Most Efficient Methods Of RNA Translation Into Proteins.
• What Is The Current State Of The DNA Replication And The Amplification Methods.
• The Limitations Of The Microarray Data Analysis.
• Is It Possible To Repair The Damage Done To The Human DNA?
• The Pros And Cons Of The Aseptic Technique: Transfection Methods.
• Purification Of The DNA: How Does Protein Purification Change Over Time?
• What Are The Objectives Of The Nucleic Acid Hybridization During The Gene Cloning Process?

Plant Pathology Biology Research Topics

Here are several interesting biology research topics concerning plant pathology:

• Natural Disease Resistance in Plants
• The Prevention Measures in Plant Pathology
• Research on Plant-Associated Microbes and Current Genomic Tools
• Literature Review on Microbial Ecology and Evolution
• Plant Diseases Management Facilitated by Modern Technology
• Plant Evolutionary Genetics
• Weedy & Invasive Plants
• Photosynthesis: Aspects & Functions
• Fertilizers’ Influence on Plants
• The Impact of Climate Change on Plant Disease Patterns
• Genetic Engineering for Disease Resistance in Crops
• Biocontrol Methods in Managing Plant Pathogens
• The Role of Soil Microbiome in Plant Disease Suppression
• Emerging Fungal Pathogens in Agricultural Crops
• Plant-Virus Interactions and Disease Management
• The Effects of Pesticides on Non-Target Plant Pathogens
• Detection and Diagnosis of Plant Pathogens Using Molecular Techniques
• Epidemiology of Plant Diseases in Changing Agricultural Landscapes
• Resistance Mechanisms in Plants Against Bacterial Pathogens
• The Impact of Invasive Species on Plant Disease Dynamics

Ecology-concerning Subjects Biology Research Topics

Undergraduates can do a proposal on Ecology-concerning subjects. First, it is one of the most relevant scientific fields as we deal with the results of human behavior all the time. Any new cool paper can shed some light of new ideas that will contribute to making the world a better place.

• Ecological and Evolutionary Factors Influencing Animal Behavior
• Essay on Relationship Between Living Forms and Their Environment
• The Affect of Human Behavior on Animal Forms in the USA
• The Ways Animal and Plants Respond to Changing Environment
• Developmental Mechanism of Resistance in Animals
• The Environmental Change and its Involvement in the Diversity of Species
• Is Global Warming Really a Threat?
• Fast Food Industry & Tropic Forests Extinction
• Environmental Psychology
• Means of Wildlife Protection
• Impact of Rain Forests Extinction
• Rare Species Protection
• The Problem of Extinction
• Renewable Energy and Environment’s Pollution
• Climate Change and Biodiversity
• Types of Pollution in Modern World
• What is Sustainability in Biology?
• Non-human factors of Extinction of Species
• Benefits of Ecotourism
• Is Extinction of Bees Real?
• Oil Spill Effects on Ocean Wildlife
• Factors and benefits of Organic Farming

Neurobiology Research Topics

• Visual Cortex & Models of Orientation
• Neuroscience in Robotic Technologies
• What is Visual-Motor Coordination Based On?
• Impact of Music on Human Brain
• Brain Injuries and Related Disorders
• Brain and Memory
• Brain Capabilities of Self-Repairing
• Genetic Defect That Contributes to Schizophrenia
• Factors and Causes Behind a Migraine
• Connection Between Gut Bacteria and Anxiety
• Can Gut Bacteria Contribute to Depression?
• Cognitive Neuroscience on Problem-Solving
• Genes and Proteins Responsible for Neurons functioning

Evolutionary Biology Research Topics

As the title implies, evolutionary biology focuses on the processes that explore the history of life forms that we encounter. Starting with the study of the natural habitats to the analysis of the biodiversity and related behaviors, it's one of the most fascinating and varied branches of Biology.

• The Natural vs Forced Evolutionary Processes as Natural Selection Takes Place
• How Can We Increase Human Awareness about The Importance of Diversity of Life on Earth
• The Heritage of Charles Darwin and Why His Theories are Still Relevant Today
• The Evolutionary Biology Processes Through The Lens of The Invertebrates
• How Do Ecology and Evolution Affect The Presence of Infectious Diseases
• Human Learning Processes and The Use of AI-based Models to Predict Evolution
• The Theory of Gene Migration and The Philosophical Importance of Spiritual Freedom
• The Importance of Evidence for The Evolution Processes: Our Common Ancestors
• What Types of Changes are Considered an Evolution When a Gene Pool Is Involved?
• Individualism as The Form of The Forced Evolution: An Ethical Aspect

Animals Biology Research Topics

Here are fascinating biology research topics related to animals. They are quite popular among students. You can submit several papers dwelling on deep analysis of one phenomenon or species.

• Factors Concerning Animal Growth
• The Obesity in Home Pets
• Traditional Dog Diet and Modern Home Pets
• Male Pregnancy Among Animals
• Is Beauty Products Testing on Animals Ethical?
• Birds Behavioral Study
• Animal Science & Food Sustainability
• Does Veganism Actually Influence Meat Production?
• Wild Animal Projects
• Fashion Industry & Animal Abuse
• Camouflage Mechanism in Sea Animals
• Discovering Primate Language and Cognitive Function

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Marine Biology Research Topics

Marine biology relates to a mixture of Biology, Chemistry, and Physics as one studies marine organisms and their behavior patterns. As marine biologists study how they interact with the environment, they use oceanography and relevant skills based on Chemistry, Physics, and Geology.

• The Salish Sea Ecology and The Use of Corals for The Understanding of Tropical Peculiarities
• The Challenges Of Quantitative Ecology Through The Lens Of Modeling
• How Can Marine Animal Behavior Be Adapted To A Certain Genetical Pool?
• Geological Oceanography: What Are The Challenges Related To Physical Limitations?
• Comparison Of The Smallest Diatoms And Their Marine Logistics
• Tourism And The Changes To The Coral Reef Ecology In 2022
• Marine Engineering And The Use Of Flexible Aquaculture
• Development Of Alternative Feeds For The Dolphins And The Tracking Systems
• What Are The Pros And Cons Of The Coastal Zone Management Currently Used In The United States?
• Biochemistry Of The Red Sea Compared To The Sea Of Azov
• The Effects of Ocean Acidification on Coral Reefs
• Marine Biodiversity in Deep-Sea Ecosystems
• The Impact of Plastic Pollution on Marine Life
• Conservation Strategies for Endangered Marine Species
• The Role of Mangroves in Coastal Ecosystems
• Marine Biotechnology and its Applications
• The Effects of Climate Change on Marine Migration Patterns
• Sustainable Fishing Practices and Marine Ecosystems
• Marine Microorganisms and their Role in the Ecosystem
• The Impact of Human Activities on Coastal Habitats

Topics on the History of Biology

There also easy issues related to the history of Biology. You can dwell on the capstone of modern science or dwell on an understanding of one crucial academic term.

• The History of Genetics
• Darwin’s Theory and Biology
• Discovering Evolution Factors
• How Archeology Impacts Animal Biology?
• Natural Selection Theory: The Discovery and Its Impact
• Effects of Whale Hunting
• Dead Branches of Evolution
• Famous Biologist Antonie van Leeuwenhoek
• Edward Jenner and the History of Vaccination
• Rachel Carson’s Perspective on Environmental Safety
• Stephen Jay Gold’s Paleontology: How History and Biology are Combined
• The Development of Cell Theory and its Impact on Biology
• Contributions of Charles Darwin to Evolutionary Biology
• The History of Genetics: From Mendel to Modern Genomics
• The Discovery and Significance of DNA Structure
• The Role of Women in the Advancement of Biology
• The Evolution of Microbiology and the Discovery of Microorganisms
• The Impact of Technology on the Progress of Biological Sciences
• Historical Perspectives on Human Anatomy Studies
• The Development of Ecological Theory and Conservation Biology

This list ends with several other fascinating research proposal topics, such as:

• Molecular and Genome Evolution
• Comparative Genomics
• The Evolutionary Biology of Infectious Diseases
• Modern Technology and Scientific Tools in Biology
• Neurobiological Explanation of Sleep
• Symbiosis in Parasites
• Metabolism & Physical Exercise

How do you choose a research topic?

When choosing a research topic, it's crucial to consider your own curiosity and passion in the subject matter. This personal connection not only makes the research process more engaging but also often leads to more diligent and thorough work. Additionally, the topic should have a significant impact or relevance in the current state of the field. This involves considering the interests of potential readers or the audience, ensuring that the topic is not only of personal interest but also of broader academic or societal importance.

Furthermore, the selection process should involve an assessment of the current state of knowledge in the field. This includes reviewing recent advances, perspective-changing publications, and ongoing debates within the discipline. A good research topic often lies at the intersection of what is currently known and the unexplored or less understood aspects of the field. By focusing on these areas, your research paper examples can contribute to the advancement of knowledge, offering new insights or solutions to existing problems. In summary, the ideal research topic is one that sparks personal interest, addresses a gap or a pressing question in the field, and has the potential to contribute meaningfully to the broader academic community.

Read also: If you are willing to  pay someone to write a research paper , let professionals write it for you. 

Start to Write Well-Grounded Biology Research

These Biology research paper topics were compiled for anyone from high-school and undergraduate students to anyone who has to deal with Biology for any reason. It all depends on the size and depths of your project, that is why you may need a proper research paper help . The topics concern the most relevant and appealing part of biological science. Start working on your thesis with reading academic literature and don't forget to ask for thesis writing help at EduBirdie. A proper review of recent publications will help you build up an argument. Always remember that the key to any of your projects is having fun. So choose the topic that you are passionate about, and go for it!

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Developing a Five-Year Research Plan

Cathy binger and lizbeth finestack, doi: 10.1044/cred-pvd-path006.

The following is a transcript of the presentation videos, edited for clarity.

What Is a Research Plan, and Why Do You Need One?

Presented by Cathy Binger

First we’re going to talk about what a research plan is, why it’s important to write one, and why five years—why not one year, why not ten years. So we’ll do some of those basic things, then Liza is going to get down and dirty into the nitty-gritty of “now what” how do I go about writing that research plan.

First of all, what is a research plan? I’m sure some of you have taken a stab at these already. In case you haven’t, this is a real personalized map that relates your projects to goals. It’s exactly what it sounds like, it’s a plan of how you’re going to go about doing your research. It doesn’t necessarily just include research.

It’s something that you need to put a little time and effort into in the beginning. And then, if you don’t revisit it, it’s really a useless document. It’s something that you need to come back to repeatedly, at least annually, and you need to make it visible. So it’s not a document that sits around and once a year you pull it out and look at it.

It can and should be designed, especially initially, with the help of a mentor or colleague. And it does serve multiple purposes, with different lengths and different amounts of detail.

I forgot to say, too, getting started, the slides for this talk were started using as a jumping off point Ray Kent’s talk from last year. So some of the slides we’ve borrowed from him, so many thanks to him for that.

But why do we want to do a research plan? Well, to me the big thing is the vision. Dr. Barlow talked this morning about your line of research and really knowing where you want to go, and this is where that shows up with all the nuts and bolts in place.

What do you want to accomplish? What do you want to contribute? Most of you are at the stage in your career where maybe you have started out with that you want to change the world scenario and realized that whatever you wanted your first research project to be, really, is your entire career. You need to get that down to the point where it is manageable projects that you can do—this is where you map out what those projects are and set reasonable timelines for that.

You want to really demonstrate your independent thinking and your own creativity, whatever that is that you then establish as a PhD student, postdoc, and beyond—this is where you come back to, okay, here’s how I’m going to go about achieving all of that.

This next point, learning to realistically gauge how long it takes to achieve each goal, this for most of us is a phenomenally challenging thing to do. Most of us really overestimate what we can do in a certain amount of time, and we learn the hard way that you can’t, and that’s another reason why you keep coming back to these plans repeatedly and learning over time what’s really manageable, what’s really doable, so we can still reach our goals and be very strategic about how we do that.

When you’re not strategic, you just don’t meet the goals. Your time gets sucked into so many different things. We need to be really practical and strategic.

Everything we do is going to take longer than we think.

I think this last one is something that maybe we don’t talk about enough. Really being honest with ourselves about the role of research in our lives. Not all of you are at very high-level research universities. Some of you have chosen to go elsewhere, where research maybe isn’t going to be playing the same role as it is for other people. The research plan for someone at an R One research intensive university is going to look quite different from someone who is at a primary teaching university. We need to be open and practical about that.

Getting sidetracked. I love this picture, I just found this picture the other day. This feels like my life. You can get pulled in so many different directions once you are a professor. You will get asked to do a thousand different things. There are lots of great opportunities that are out there. Especially initially, it’s tempting to say yes to all of them. But if you’re going to be productive, you have to be very strategic. I’m going to be a little bit sexist against my own sex here for a minute, but my observation has been that women tend to fall into this a little bit more than men do in wanting to say yes and be people pleasers for everything that comes down the pike.

It is a professional skill to learn how to say no. And to do that in such a way that you are not burning bridges as you go down the path. That is a critical skill if you are going to be a successful researcher. I can’t tell you how many countless people I’ve seen who are very bright, very dedicated, have the skills that it takes in terms of doing the work—but then they are not successful because they’ve gotten sidetracked and they try to be too much of a good citizen, give too much service to the department, too much “sure I’ll take on that extra class” or whatever else comes down the line.

I just spoke with a professor recently who had something like five hours a week of office hours scheduled every single week for one class. Margaret is shaking her head like “are you kidding?” That’s crazy stuff. But he wanted to really support his students. His students loved him, but he was not going to get tenure. That’s the story.

So we have to be very thoughtful and strategic, and what can help you with this, and ASHA very firmly recognizes which is why we’re here—is that your mentors in your life should be there to help you learn these skills and learn what to say yes to, and learn what to say no to. I’ve learned to say things like, “Let me check with my mentor before I agree to that.” And it gives you a way out of that. The line that I use a lot is, “Let me check with my department head” or, I just said this to somebody last week, “I just promised my department head two weeks ago that I would only do X number of external workshops this year, so I’m going to have to turn this one down.” Those are really important skills to develop.

And having that research plan in place that you can go back to and say, know what, it’s not on my plan I can’t do it. If I do it—I have to go back to my research plan and figure out what I’m going to kick off in order to review this extra paper, in order to take on this extra task. The plan also helps me to know exactly what to say no to. And to be very direct and have a very strong visual.

I actually have my research plan up on a giant whiteboard in my office, so I can always go back to that and see where I am, and I can say, “Okay, what am I going to kick off of here? Nothing. Okay, I have to say no to whatever comes up.” Just be strategic. This is where I see most beginning professors really end up taking that wrong fork in the road—taking that right instead of that left, and ending up not being the successful researcher that they wanted to be.

What evidence supports research planning? This was something Ray Kent had found. That a recent analysis had found that postdoc scholars who developed a written plan with their postdoc advisers were much more productive than those who didn’t. And your performance during a postdoc—and I know many of you have either finished your postdoc or decided not to—so more simply, just during those first six years, the decisions you make really do establish the foundation for the rest of your professional life. It’s very important to get started and get off on the right foot.

I love this quote, I just found it the other day: “Productivity is never an accident. It is always the result of a commitment to excellence, intelligent planning, and focused effort.”

What we see with productivity is that postdoc scholars who developed written productivity expectations with their advisers were more productive than those who didn’t. You see 23% more papers submitted, 30% more first-author papers, and more grant proposals as well.

So why five years? I’m going to start with number 5. It’s long enough to build a program of research, but short enough to deal with changing circumstances. That’s really the long and the short of the matter. As well as these other things as well that I won’t take the time to go through point by point.

What Should a Five-Year Plan Include?

Presented by Lizbeth Finestack

So, thinking about a five-year research plan, I like to think about it like your major “To Do List.” It’s what you’re going to accomplish in five years. Start thinking: What is going to be on my to do list?

You can also think about it like: Okay, I have research. I’ve got to do research. Maybe think about this as one big bucket, or maybe one humongous silo. I have some farm themes going on. Cathy was just on a farm, so I thought I’d tie that in.

So here’s your big silo. You can call that your research silo.

But more realistically, you need to think about it like separate buckets, separate silos, where research is just one of those. Just like Cathy indicated, there’s going to be lots of other things coming up that you’re going to have to manage. They are going to have to be on your to do list, you need to figure out how to fit everything in.

What all those other buckets or silos are, are really going to depend on your job. And maybe the size of the silos, and the size of the buckets are going to vary depending on where you are, what the expectations are at your institution.

That’s important to keep in mind, and Cathy said this too, it’s not going to be the same for everyone. The five-year plan has to be your plan, your to do list.

Here are some buckets or some silos that I have on my list and the way that I break it up, this is just one example, take it or leave it.

The first three are all very closely related, right? Thinking about grants, thinking about research, thinking about publications. I’m going to define grants as actual writing, getting the grant, getting the money.

Research is what you’re going to do once you get that money. Steps you need to take before you are getting the money. Any sorts of projects, the lab work, that’s why I have the lab picture there. Of course, publications are part of the product—what’s coming out of the research—but it also cycles in because you need publications to support that you are a researcher to apply for funding and show you have this line of research that you’ve established and you’ll be able to continue. So, those first three are really closely related. And that’s where I’ll go next. And then have teaching and service you see here at the bottom.

So thinking about research, in that broad sense. As you’re writing your five-year plan you’re going to want to think of, “What’s my long-term goal?” There’s lots of ways to think of long-term goals. You could think, before I die, this is what I want to accomplish. For me I kind of have that. My long-term goal is that I’m going to find the most effective and efficient interventions for kids with language impairment. Huge broad goal. But within that I can start narrowing it down.

Where am I within that? Within the next five years or maybe the next ten years, what is it I want to accomplish towards that goal. Then start thinking about: In order to accomplish that goal, what are the steps I need to take? Starting to break it down a little bit. Then it’s also going to be really important to think: where are you going to start? Where are you now? What do you need to have happen? And is it reasonable to accomplish this goal within five years? Is it going to take longer? Maybe you could do it in a couple years? Start thinking about the timeline that’s going to work for you.

Then thinking about your goals—and everyone’s program is going to be different, like I said, there’s going to be a lot of individual needs, preferences. So it might be the case that you have this one long-term goal that you’re aiming for. Long-term goal in the sense of, maybe, what you want to study in your R01, perhaps something like that. But in order to get to that point, you’re going to have several short-term goals that need to be accomplished.

Or maybe it’s the case that you have two long-term goals. And with each of those you’re going to have multiple short-term goals that you’re working on. Maybe the scope of each of these long-term goals is a little bit less than in that first scenario.

Start thinking about my research, what I want to do, and how it might fit into these different circumstances.

Also thinking about your goals, this is a slide from Ray Kent from last year, was thinking about the different types of projects you might want to pursue, and thinking about ones that are definitely well on your way. They are safe bets. You have some funding. They are going to lead directly into your longer-term plan.

Those are going to be your front burner—things you can easily focus on. That said, don’t put everything there.

You can also have things on the back burner. Things that really excite you, might have huge benefits, big pay. But you don’t want to spend all of your time there because they could be pretty risky.

Start thinking about where you’re putting your time. Are you putting it all on this high-risk thing that if it doesn’t pan out you’re going to be in big trouble? Or balancing that somewhat with your front burner. Making that steady progress that will lead directly to help fund an R01 or whatever the mechanism that you’re looking for.

Then, thinking about your goals—if you have multiple long-term goals, or thinking about your short-term goals, you could think about your process. Is it something where you need to do study 1 then study 2, then study 3—each of those building on each other, that’s leading to that long-term goal. In many cases, that is the case, where you have to get information from the first study which is going to lead directly to the second study and so forth.

Or is it the case that you can be working on these three short-term goals simultaneously? Spreading your resources at the same time. Maybe it will take longer for any one study, but across a longer period of time you’ll get the information that you need to reach that long-term goal.

Lots and lots of different ways to go about it. The important thing is to think about what your needs are and what makes the most sense for you.

Here’s my own little personal example. Starting over here, I have my dissertation study. My dissertation study was this early efficacy study looking at one treatment approach using novel forms that really can’t generalize to anything too useful, but it was important.

Then I did a follow up study, where I was taking that same paradigm, looking to see where kids with typical development perform on the task. So I have these two studies, and they served as my preliminary studies for an R03. So I just finished an R03 where I was looking at different treatment approaching for kids with primary language impairment. At the same time, while conducting my R03, I’m also looking at some different approaches that might help with language development. Also conducting surveys to see what current practices are.

I have these three projects going on simultaneously, that are going to lead to a bigger pilot study that are going to feed directly into my R01. All of this will serve as preliminary data to go into an R01.

Start thinking about your projects, what you have. Maybe starting with your dissertation project or work that you’re doing as a postdoc as seeing how that can feed into your long-term goal. And really utilizing it, building on it, to your benefit.

That’s all fine and dandy. You can draw these great pictures. But you still have to break it down some more. It’s not like, “Oh, I’m just going to do this project.” There are other steps involved, and lots of the time these steps are going to be just as time consuming.

Starting to think about: well, if you have the funding. Saying, “I want to do this study, but I have no money to do it.” What are the steps in order to get the money to do it? Do you have a pilot study? What do you need?

Start thinking about the resources? Do you need to develop stimuli, protocols, procedures? Start working on that. All of these can be very time consuming, and if you don’t jump on that immediately, it’s going to delay when you can start that project.

Thinking about IRB. Relationships for recruitment, if you’re working with special populations especially? Do you have necessary personnel, grad students, people to help you with the project? Do you need to train them? What’s the timeline of the study?

Start thinking about all these pieces, and how they are going to fit in that timeline.

This is one way that might help you start thinking about the resources that you need. This is online—Ray Kent had it in his talk, and when I was doing my searches I came across it too and I have the website at the end. Just different ways to think about the resources you might need.

Let’s talk about mapping it out. You have your long-term goal. You have your short-term goals. You’re breaking it down thinking about all those little steps that you need to accomplish. We gotta put it on a calendar. When is it going to happen?

This is an example—you might have your five years. Each month plugging in what are you going to accomplish by that time. Maybe it’s when are grant applications due? It’s going to be important to put those on there to go what do I need to do to make that deadline. Maybe it’s putting when you’re going to get publications out. Things like that.

Honestly, looking at this drives me a little bit crazy, it seems a bit overwhelming. But it’s important to get to these details.

This is an example from, I did Lessons for Success a few years ago and they had their format for doing your plan. I wrote out all my projects, started thinking about all the different aspects. So if something like this works for you, by all means you could use that type of procedure.

Here’s a grid that Ray Kent showed last year. We’re breaking it down by semester. Thinking about each of your semesters, what manuscripts you’re going to be working on, what data collection, your grant applications. Starting to get into some of those other buckets: course preparation, conference submissions.

We also need to include teaching and service.

You probably can’t see this very well. This is similar to that last slide Ray Kent had used last year.

I have my five year plan: what studies I want to accomplish, start thinking about breaking it down.

Then at the beginning of each semester, I fill in a grid like this. Where at the top, I have each of my buckets. I have my grant bucket, my writing bucket which is going to include publications. I also include doing article reviews in my writing bucket, because that’s my writing time. My teaching bucket, my research bucket. Then at the end, my service bucket.

At the beginning of the semester, I think about the big things I want to accomplish. I list those at the top. Then at the beginning of each month, I say, okay what are the things I’m going to accomplish this month, write those in. Then at the beginning of each week, I start looking at whether I’m dedicating any time to the things I said I was going to do that month. I start listing those out saying, this is the amount of time I’m going to spend on that. Of course, I have to take data on what I actually do, so I plug in how much time I’m spending on each of the tasks. Then I graph it, because that’s rewarding to see how much time you’re spending on things, and I get a little side-tracked sometimes.

Think about a system that will help you keep on track, to make sure you’re meeting the goals that you want to meet in terms of your research. But also getting the other things done that you need to get done in terms of teaching and service.

Discussion and Questions

Compiled from comments made during the Pathways 2014 and 2015 conferences. (Video unavailable.)

Building Flexibility into Your Five-Year Plan Comments by Ray Kent, University of Wisconsin-Madison

The five-year plan is not a contract. It’s a map or a compass. A general set of directions to help you plan ahead. It’s not even a contract with yourself, because it will inevitably be revised in some ways.

Sometimes cool things land in your lap. Very often it turns out that through serendipity or whatever else, you find opportunities that are very enticing. Some of those can be path to an entirely new line of research. Some of them can be a huge distraction and a waste of time. It’s a really cool part of science that new things come along. If we put on blinders and say, “I’m committed to my research plan,” and we don’t look to the left or the right, we’re really robbing ourselves of much of the richness of the scientific life. Science is full of surprises, and sometimes those surprises are going to appear as research projects. The problem is you don’t want to redirect all your time and resources to those until you’re really sure they are going to pay off. I personally believe, some of those high risk but really appealing projects are things you can nurse along. You can devote some time and build some collaborations – far enough to determine how realistic and viable they are. That’s important because those things can be the core of your next research program.

It’s very easy to get overcommitted. We all know people who always say “yes”—and we know those people, and they are often disappointing because they can’t get things done. It’s important to have new directions, but limit them. Don’t say, “I’m going to have 12 new directions this year.” Maybe one or two. Weigh them carefully. Talk about them with other people to get a judgment about how difficult it might be to implement them. It enriches science: not only our knowledge, but the way we acquire new knowledge. A psychologist, George Miller—this is the guy with the magic number 7 +- 2—when we interviewed him years ago at Boystown, he said, “My conviction is that everybody should be able to learn a new area of study within three months.” That’s what he thought for a scientist was a goal.

The idea is that you can learn new things. And that’s very important because when you think of it in terms of a 30-year career, how likely is it that the project that you’re undertaking at age 28 is the same project you’ll be working on at age 68? Not very likely. You’re going to be reinventing yourself as a scientist. And reinventing yourself is one of the most important things you can do, because otherwise you’re going to be dead wood. Some projects aren’t worth carrying beyond five or ten years. They have an expiration date.

Building Risk into Your Five-Year Plan Comments by Ray Kent, University of Wisconsin-Madison

Your doctoral study should generally be low-risk research. As you move into a postdoctoral fellowship, think about having two studies—one low-risk, one high-risk with a potential for high impact. At this time you can begin to play the risk factor a little bit differently.

When you are tenure-track you can have a mix of significance with low-risk and high-risk studies. And when you are tenured, then you can go for high risk, clinical trials, and collaborations. Because you have established your independence, so you do not need to worry about losing your visibility. You can be recognized as a legitimate member of the team.

As you plan your career, you should take risk into account. Just as you manage your money taking risk into account, we should manage our careers taking risk into account. I have met people who did not really think about that, and they embarked on some very risky procedures and wasted a lot of time and resources with very little to show for it. For example, don’t put everything into an untested technology basket. You want to be using state of the art technology, but you want to be sure it is going to give you what you need.

Other Formats and Uses of Your Research Plan Audience Comments

• If you do your job right with your job talk, there’s a lot of cross-pollination between your job talk and your research plan. Ideally your job talk tells your colleagues that this is the long-term plan that you have. And they shouldn’t be surprised when you submit a more detailed research plan. They should say, “okay this is very consistent with the job talk.” In my view, the job talk should be a crystal summary of the major aspects of that research program. Of course, much of the talk will be about a specific project or two—but it should always be embedded within the larger program. That helps the audience keep sight of the fact that you are looking at the program. You can say that this is one project that I’ve done, and I plan to do more of these, and this is how they are conceptually related. That’s a good example of why the research plan has multiple purposes – it can be a research statement, it can be the core of your job talk, it can be the nature of your elevator message, and it can be a version of your research plan for a K award application or R01 application or anything else of that nature.
• I think what’s useful is to actually draft your NIH biosketch. The new biosketch has a section called “contributions to science.” It’s really helpful to think about all your projects. It’s hard to start with a blank sheet of paper. But to have it in the format of a biosketch can be really helpful.

Avoiding Overcommitment Audience Comments

• One of the things that is amazing about planning is that if you put an estimate on the level of effort for each part of your plan, you’ll quickly find that you are living three or four lives. Some 300% of your time is spent. It’s helpful for those of us who might share my lack of ability to see constraints or limitations to reel it back and say, “I have a lot on my plate.” Which allows you to say no—which is not something we all do very well when it comes to those nice colleagues and those people you want to impress nationally and connect with. But it allows you to look at what’s planned and go, “I don’t know where I’d find the time to do that.” Which will hopefully help you stay on track.
• I keep a to do list, but I also keep a “to not do” list. One of the things I will keep on my plan is the maximum number of papers I will review in a year. If I hit that number in March, that’s it. I say no to every other paper that comes down the pike. That’s something to work out with your mentor as far as what’s realistic and what’s okay for you. Every time I get a request, I think, “That’s my reading and writing time, so what am I willing to give up. If it means I won’t be able to write on my own paper this week, am I willing to do this?”

Staying on Schedule with Reading, Writing, and Reviewing Audience Comments

• You have to do what works for you. Some people do wait for big blocks of time for writing—which are hard to come by. But the most important thing is to block off your time. Put it on your schedule, or it is the first thing that will get pushed aside.
• Another thing I’ve done with some of my colleagues is writing retreats. So maybe once a year, twice a year, we’ll get together. Usually we’ll go to a hotel or somewhere, and we’re just writing. It’s a great way to get a jumpstart on a project. Like, I need to sit down and start this manuscript, and you can keep going once you’ve got that momentum.
• My input would be that you really have to write all the time, every day. It’s a skill. I’ve found that if I take time off, my writing deteriorates. It’s something you need to keep up with.
• I would look at it like a savings account that you put money into on a daily, weekly, monthly basis. The flip side of writing is reading. I would read constantly, widely, and not just in the discipline. That will give you not only a breadth in terms of your understanding of your field and the world around you, but it will also give you an incentive to make your own contributions. I think we don’t talk enough about the comprehensive side to this, and being receptive to the reading. I have a book, or something, by my bedside every night. And I read that until I fall asleep every night. And it’s done me in good stead over the years.
• Reviewing articles can help advance your career, but it is something you need to weigh carefully as a draw on your time. You get a lot from it. You get to see what’s out there. You get to see what’s coming down the pipe before publication. To me that’s a huge benefit. You get to learn from other people’s writing, and that’s part of your reading you get to do. But it is time consuming. And it depends on the kinds of papers you get. Sometimes you’re lucky and sometimes you’re not.
• If someone else is reviewing your grants and your articles, at some point you owe it back. You should at least be in break-even mode. Now, pre-tenure or postdoc your mentor should be doing that or senior faculty in the department. But there are so many articles to review. I review so many articles, but I am also at the tail end of my career. The bottom line is, if you don’t put on your schedule that if you don’t put time on your schedule for reading, reviewing articles forces you to look at and think about the literature, so you can be accomplishing what you owe back to the field—and at the same time, staying one step ahead knowledge wise. It forces you to do what you should be doing all along, which is keeping up with the literature.

Further Reading: Web Resources

Golash-Boza, T. (2014). In Response to Popular Demand, More on the 5-Year Plan. The Professor Is In . Available at http://theprofessorisin.com/2014/05/09/in-response-to-popular-demand-more-on-the-5-year-plan

Kelsky, K. (2010). The Five-Year Plan for Tenure-Track Professors. Get a life, PhD . Available at http://getalifephd.blogspot.com/2010/07/five-year-plan-for-tenure-track.html

National Association of Geoscience Teachers (NAGT). (2012). Planning Worksheets . Planning your Research Program (Available from the Science Education Resource Center at Carelton College Website at http://serc.carleton.edu/).

Pfirman, S., Bell, R., Culligan, P., Balsam, P. & Laird, J. (2008) . Maximizing Productivity and Recognition , Part 3: Developing a Research Plan. Science Careers. Available at http://sciencecareers.sciencemag.org/career_magazine/previous_issues/articles/2008_10_10/caredit.a0800148

Cathy Binger University of New Mexico

Lizbeth Finestack University of Minnesota

Based on a presentation and slides originally developed by Ray Kent, University of Wisconsin-Madison.

Presented at Pathways (2015). Hosted by the American Speech-Language-Hearing Association Research Mentoring Network.

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Copyrighted Material. Reproduced by the American Speech-Language-Hearing Association in the Clinical Research Education Library with permission from the author or presenter.

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Year 7 - Living systems - L1 Information sheets (Organelles)

Subject: Biology

Age range: 7-11

Resource type: Worksheet/Activity

Last updated

9 September 2024

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Information sheet for carousel/circus activity. Could also be used as a research activity for homework. Each information sheet has information on the different organelles in animal and plant cells, and their functions.

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